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Thyrotoxicosis due to functioning metastatic follicular thyroid cancer

Year 2016, , 339 - 41, 15.10.2016

Sadiye Altun Tuzcu , Faruk Kilinc , Zafer Pekkolay , Hikmet Soylu Alpaslan Kemal Tuzcu

https://doi.org/10.17546/msd.14352

Abstract

Thyrotoxicosis is a common condition associated with excess circulating thyroid hormones. Rarely, thyrotoxicosis can be developing due to functioning metastatic thyroid carcinoma. Most of patients with functional thyroid cancer metastases have had normal thyroxine (T4) concentrations but high serum triiodothyronine (T3-thyrotoxicosis). Inappropriately supressed TSH levels with normal T4 levels may be helpful to suspect T3 thyrotoxicosis. In this case report we present a case of thyrotoxicosis due to metastatic follicular thyroid cancer with a huge metastatic lesion.

Keywords

metastatic follicular thyroid cancer thyrotoxicosis

References

  • Vaidya B, Pearce SH. Diagnosis and management of thyrotoxicosis. BMJ. 2014; 21:349:g 5128.
  • Nakashima T, Inoue K, Shiro-ozu A, et al. Predominant T3 synthesis in the metastatic thyroid carcinoma in a patient with T3-toxicosis. Metabolismi 1981;30:327-330.
  • Paul SJ, Sisson JC. Thyrotoxicosis caused by thyroid cancer. Endocrinol Metab Clin North Am. 1990;19:593-612.
  • Russo D, Tumino S, Arturi F, et al. Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma. J Clin Endocrinol Metab.1997; 82:735-738.
  • Miyauchi A, Takamura Y, Ito Y, et al. 3,5,3'-Triiodothyronine thyrotoxicosis due to increased conversion of administered levothyroxine in patients with massive metastatic follicular thyroid carcinoma. J Clin Endocrinol Metab 2008; 93:2239.
  • Kasagi K, Takeuchi R, Miyamoto S, et al. Rapid Control of T3 Thyrotoxicosis in Patients with Metastatic Follicular Thyroid Cancer Treated Metastatic thyroid cancer presenting as thyrotoxicosis: report of three cases. Clin Endocrinol (Oxf) 1994; 40:429.

Thyrotoxicosis formation due to functioning metastatic follicular thyroid cancer

Year 2016, , 339 - 41, 15.10.2016

Sadiye Altun Tuzcu , Faruk Kilinc , Zafer Pekkolay , Hikmet Soylu Alpaslan Kemal Tuzcu

https://doi.org/10.17546/msd.14352

Abstract

References

  • Vaidya B, Pearce SH. Diagnosis and management of thyrotoxicosis. BMJ. 2014; 21:349:g 5128.
  • Nakashima T, Inoue K, Shiro-ozu A, et al. Predominant T3 synthesis in the metastatic thyroid carcinoma in a patient with T3-toxicosis. Metabolismi 1981;30:327-330.
  • Paul SJ, Sisson JC. Thyrotoxicosis caused by thyroid cancer. Endocrinol Metab Clin North Am. 1990;19:593-612.
  • Russo D, Tumino S, Arturi F, et al. Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma. J Clin Endocrinol Metab.1997; 82:735-738.
  • Miyauchi A, Takamura Y, Ito Y, et al. 3,5,3'-Triiodothyronine thyrotoxicosis due to increased conversion of administered levothyroxine in patients with massive metastatic follicular thyroid carcinoma. J Clin Endocrinol Metab 2008; 93:2239.
  • Kasagi K, Takeuchi R, Miyamoto S, et al. Rapid Control of T3 Thyrotoxicosis in Patients with Metastatic Follicular Thyroid Cancer Treated Metastatic thyroid cancer presenting as thyrotoxicosis: report of three cases. Clin Endocrinol (Oxf) 1994; 40:429.
There are 6 citations in total.

Details

Journal Section Case Reports
Authors

Sadiye Altun Tuzcu

Faruk Kilinc

Zafer Pekkolay

Hikmet Soylu This is me

Alpaslan Kemal Tuzcu

Publication Date October 15, 2016
Published in Issue Year 2016

Cite

APA Tuzcu, S. A., Kilinc, F., Pekkolay, Z., Soylu, H., et al. (2016). Thyrotoxicosis due to functioning metastatic follicular thyroid cancer. Medical Science and Discovery, 3(10), 339-41. https://doi.org/10.17546/msd.14352
AMA Tuzcu SA, Kilinc F, Pekkolay Z, Soylu H, Tuzcu AK. Thyrotoxicosis due to functioning metastatic follicular thyroid cancer. Med Sci Discov. October 2016;3(10):339-41. doi:10.17546/msd.14352
Chicago Tuzcu, Sadiye Altun, Faruk Kilinc, Zafer Pekkolay, Hikmet Soylu, and Alpaslan Kemal Tuzcu. “Thyrotoxicosis Due to Functioning Metastatic Follicular Thyroid Cancer”. Medical Science and Discovery 3, no. 10 (October 2016): 339-41. https://doi.org/10.17546/msd.14352.
EndNote Tuzcu SA, Kilinc F, Pekkolay Z, Soylu H, Tuzcu AK (October 1, 2016) Thyrotoxicosis due to functioning metastatic follicular thyroid cancer. Medical Science and Discovery 3 10 339–41.
IEEE S. A. Tuzcu, F. Kilinc, Z. Pekkolay, H. Soylu, and A. K. Tuzcu, “Thyrotoxicosis due to functioning metastatic follicular thyroid cancer”, Med Sci Discov, vol. 3, no. 10, pp. 339–41, 2016, doi: 10.17546/msd.14352.
ISNAD Tuzcu, Sadiye Altun et al. “Thyrotoxicosis Due to Functioning Metastatic Follicular Thyroid Cancer”. Medical Science and Discovery 3/10 (October 2016), 339-41. https://doi.org/10.17546/msd.14352.
JAMA Tuzcu SA, Kilinc F, Pekkolay Z, Soylu H, Tuzcu AK. Thyrotoxicosis due to functioning metastatic follicular thyroid cancer. Med Sci Discov. 2016;3:339–41.
MLA Tuzcu, Sadiye Altun et al. “Thyrotoxicosis Due to Functioning Metastatic Follicular Thyroid Cancer”. Medical Science and Discovery, vol. 3, no. 10, 2016, pp. 339-41, doi:10.17546/msd.14352.
Vancouver Tuzcu SA, Kilinc F, Pekkolay Z, Soylu H, Tuzcu AK. Thyrotoxicosis due to functioning metastatic follicular thyroid cancer. Med Sci Discov. 2016;3(10):339-41.