Research Article

The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures

Volume: 4 Number: 11 November 30, 2017
EN

The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures

Abstract

Objective:  We aimed to investigate the effects of adding 5mg dexamethasone to 0.5% levobupivacaine on postoperative analgesia after US-guided infra-clavicular block.

Methods: This prospective study was performed at Sehitkamil Goverment Hospital, Gaziantep, Turkey, between september 2012 and february 2013. Ninty patients presented with fracture of forearm bones. Patients were randomly allocated to receive ultrasound guided infraclavicular brachial plexus blockade using levobupivacaine 0.5% in conjunction with or without dexamethasone 5 mg. In Group I (n=45), 0.9% NaCl was added as adjuvant. In Group II (n=45), 5 mg dexamethasone was added to 0.5% levobupivacaine and surgical anesthesia was provided. Postoperative pain control was provided by using morphine with intravenous patient controlled analgesia (IVPCA). one mg bolus dose was administered, continued with limit of 5 mg/hour and 10 min of locking time. Verbal ranting scala (VRS), patient satisfaction score (PSS) and total morphine consumption were controlled for postoperative 48 hours.

Results: Sensory block onset time was significatly longer in group I. Sensory block time was longer in group II. PSS was higher in group II, total morphine consumption was found more in group I, VRS was significantly higher in group I.

Conclusion: Application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures reduces sensory block initiation time, prolongs duration of Sensorial Block and reduces analgesic consumption.

Keywords

References

  1. 1. Chin KJ, Singh M, Velayutham V et. al. Infraclavicular brachial plexus block for regional anaesthesia of the lower arm. Anesth Analg 2010; 111: 1072.
  2. 2. De Tran OH, Clemente A, Doan J et. al. Brachial plexus blocks: a review of approaches and techniques. Can J Anaesth 2007; 54: 662-74.
  3. 3. Klaastad Ø, Smith HJ, Smedby O et. al. A novel infraclavicular brachial plexus block: the lateral and sagittal technique, developed by magnetic resonance imaging studies. Anesth Analg 2004; 98(1): 252-6.
  4. 4. Halasznski TM. Ultrasound brachial plexus anesthesia for upper extremity surgery: Essentials of our current understanding, 2011. Curr Opin Anaesthesiol 2011; 24: 581-91.
  5. 5. Gürkan Y, Acar S, Solak M et. al. Comparison of nerve stimulation vs. ultrasound-guided lateral sagittal infraclavicular block. Acta Anaesthesiol Scand 2008; 52(6): 851-5.
  6. 6. Liu S, Carpenter RL, Chiu AA et. al. Epinephrine prolongs duration of subcutaneous infiltration of local anesthesia in a dose-related manner. Correlation with magnitude of vasoconstriction. Reg Anesth 1995; 20: 378–384.
  7. 7. McCartney CJL, Duggan E, Apatu E. Should we add clonidine to local anesthetic for peripheral nerve blockade? A qualitative systematic review of the literature. Reg Anesth Pain Med 2007; 32: 330–338
  8. 8. Förster JG, Rosenberg PH. Clinically useful adjuvants in regional anaesthesia. Curr Opin Anaesthesiol 2003; 16: 477–486.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Ertugrul Kilic
Dept of Anesthesiology and Reanimation, Şehitkamil State Hospital, Gaziantep
Türkiye

Burcin Karsli This is me
Dept of Orthopedics, Şehitkamil State Hospital, Gaziantep
Türkiye

Mustafa Evrenos
Dept of Plastic Surgery, Şehitkamil State Hospital, Gaziantep
Türkiye

Murat Erkek This is me
Dept of Orthopedics, Şehitkamil State Hospital, Gaziantep
Türkiye

Ayse Mizrak This is me
Dept of Anesthesiology and Reanimation, Gaziantep University Medical School, Gaziantep
Türkiye

Publication Date

November 30, 2017

Submission Date

October 29, 2017

Acceptance Date

November 9, 2017

Published in Issue

Year 1970 Volume: 4 Number: 11

APA
Kilic, E., Karsli, B., Evrenos, M., Erkek, M., & Mizrak, A. (2017). The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Medical Science and Discovery, 4(11), 80-85. https://doi.org/10.17546/msd.347650
AMA
1.Kilic E, Karsli B, Evrenos M, Erkek M, Mizrak A. The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Med Sci Discov. 2017;4(11):80-85. doi:10.17546/msd.347650
Chicago
Kilic, Ertugrul, Burcin Karsli, Mustafa Evrenos, Murat Erkek, and Ayse Mizrak. 2017. “The Effects of Application of 0.5% Levobupivacaine Together With 5 Mg Dexamethasone for Infra-Clavicular Block in Surgical Treatment of Forearm Fractures”. Medical Science and Discovery 4 (11): 80-85. https://doi.org/10.17546/msd.347650.
EndNote
Kilic E, Karsli B, Evrenos M, Erkek M, Mizrak A (November 1, 2017) The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Medical Science and Discovery 4 11 80–85.
IEEE
[1]E. Kilic, B. Karsli, M. Evrenos, M. Erkek, and A. Mizrak, “The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures”, Med Sci Discov, vol. 4, no. 11, pp. 80–85, Nov. 2017, doi: 10.17546/msd.347650.
ISNAD
Kilic, Ertugrul - Karsli, Burcin - Evrenos, Mustafa - Erkek, Murat - Mizrak, Ayse. “The Effects of Application of 0.5% Levobupivacaine Together With 5 Mg Dexamethasone for Infra-Clavicular Block in Surgical Treatment of Forearm Fractures”. Medical Science and Discovery 4/11 (November 1, 2017): 80-85. https://doi.org/10.17546/msd.347650.
JAMA
1.Kilic E, Karsli B, Evrenos M, Erkek M, Mizrak A. The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Med Sci Discov. 2017;4:80–85.
MLA
Kilic, Ertugrul, et al. “The Effects of Application of 0.5% Levobupivacaine Together With 5 Mg Dexamethasone for Infra-Clavicular Block in Surgical Treatment of Forearm Fractures”. Medical Science and Discovery, vol. 4, no. 11, Nov. 2017, pp. 80-85, doi:10.17546/msd.347650.
Vancouver
1.Ertugrul Kilic, Burcin Karsli, Mustafa Evrenos, Murat Erkek, Ayse Mizrak. The effects of application of 0.5% levobupivacaine together with 5 mg dexamethasone for infra-clavicular block in surgical treatment of forearm fractures. Med Sci Discov. 2017 Nov. 1;4(11):80-5. doi:10.17546/msd.347650