Developing Hemophagocytic Syndrome during the transformation of Chronic Lymphocytic Leukemia: Case reports of t(7;14), t(14;19) and deletion of 17 p

Abstract

Chronic lymphocytic Leukemia (CLL) is the most common form of leukemia in adults. Clinical findings may broad range vary. Detecting some deletions using the FISH method may help us to foresee the progression of the disease and to choose a better treatment method in healing the patient. In this case report, we will present you a CLL patient with t(7;14), t(14;19) and  17p deletions, which are known for bad prognosis, developing autoimmune hemolytic anemia which is refractor to the treatment. This patient unfortunately died due to a clinical form of hemophagocytic syndrome including prolymphocytic transformation.  

Keywords

• Chronic Lymphocytic Leukemia,Hemophagocytic Syndrome,hematologic malignancies,t(7;14),t(14;19),17p,deletion

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