Year 2014,
Volume: 1 Issue: 1, 27 - 30, 01.03.2014
Abstract
Congenital afibrinogenemia is a rare bleeding disorder. It may be manifested as umblical, mucosal, intramuscular, intraarticular, or life-threatening intracranial bleeding. A third-day-old infant was admitted for umblical cord bleeding, and was found to have a prolonged prothrobin time [PT], and activated partial thromboplastin time [aPTT], and a very low fibrinogen level. He was diagnosed as congenital afibrinogenemia, and reported for the rarity of disease, and discussion of novel therapeutic approaches
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- Conflict of Interest
- The authors declared that they had no
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- Copyright © 2014 The Author(s); This is an open-access article distributed under the terms of the Creative Commons Attribution
- License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium,
- provided the original work is properly cited.
Year 2014,
Volume: 1 Issue: 1, 27 - 30, 01.03.2014
Abstract
References
- Conflict of Interest
- The authors declared that they had no
- anaesthesiology. 2008;25(6):519-21. European journal of 14.
- Cronin C, Fitzpatrick D, Temperley I. Multiple pulmonary
- emboli in a patient with afibrinogenaemia. Acta
- haematologica. 1988;79(1):53-4. 15.
- De Mattia D, Regina G, Giordano P, Del Vecchio GC,
- Altomare M, Schettini F. Association of congenital
- afibrinogenemia and K-dependent protein C deficiency--a
- case report. Angiology. 1993;44(9):745-9. 16. de Moerloose P, Neerman-Arbez M. Congenital fibrinogen disorders. Seminars in thrombosis and hemostasis. 2009;35(4):356-66. 17. Peyvandi F, Haertel S, Knaub S, Mannucci PM. Incidence of bleeding symptoms in 100 patients with inherited afibrinogenemia or hypofibrinogenemia. Journal of thrombosis and haemostasis : JTH. 2006;4(7):1634-7. 18.
- Parameswaran R, Dickinson JP, de Lord S, Keeling DM,
- Colvin BT. Spontaneous intracranial bleeding in two
- patients with congenital afibrinogenaemia and the role of
- replacement therapy. Haemophilia : the official journal of
- the World Federation of Hemophilia. 2000;6(6):705-8.
- Copyright © 2014 The Author(s); This is an open-access article distributed under the terms of the Creative Commons Attribution
- License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium,
- provided the original work is properly cited.
There are 18 citations in total.
Details
| Primary Language | English |
|---|---|
| Journal Section | Case Reports |
| Authors | |
| Publication Date | March 1, 2014 |
| Published in Issue | Year 2014 Volume: 1 Issue: 1 |
