Overview Of Occupational Cancer

Abstract

Cancers are a heterogeneous group of diseasesin terms of signs, symptoms, prognosis, treatmentand management. Main characteristics includeuncontrolled cell proliferation and involvement ofnear and distant organs. Only 5-10% of cellularchanges leading to development of cancer couldbe explained by hereditary mechanisms and remaining large group is related to environmental factors. Of those, cancers due to occupational riskfactors are defined as occupational cancers. Percentage of occupational cancers in all cancersvaries between 3-10% according to different researches

Keywords

• Cancer,IARC,occupational diseases

MESLEKİ KANSERLERE GENEL BAKIŞ

Abstract

Kanser, hücrelerin çeşitli nedenlerle kontrolsüz çoğalması ve komşu ya da uzak organlara yayılması ile karakterize olan; belirti ve bulgular, klinik seyir, tedavi ve yaklaşım açısından farklılık gösteren hastalıkların genel grubudur. Kansere sebep olan hücresel değişikliklerin yalnızca %5-10’u kalıtsal mekanizmalarla açıklanmakta olup kalan büyük kısmı çevresel faktörlerle ilgilidir. Çevresel etkenlerden mesleki risk faktörlerine bağlı olarak gelişen kanserler mesleki kanserler olarak adlandırılmaktadır. Farklı araştırma sonuçlarına göre mesleki kanserler, tüm kanserlerin %3-10’nu oluşturmaktadır

Keywords

• Kanser,IARC,meslek hastalıkları

References

1. Türkiye İstatistik Kurumu. “2015 Ölüm Nedeni İstatistikleri” http://www.tuik.gov.tr/Pre HaberBultenleri.do?id=21526 (10/10/2016)
2. Amerika Birleşik Devletleri Hastalık Kontrol ve Korunma Merkezleri. “National Center for Health Statistics Leading Causes of Death 2015” http://www.cdc.gov/nchs/fastats/leading-causes-of- death.htm (10/10/2016)
3. Fischman ML, Rugo HS. “Occupational Cancer” İçinde: LaDou J, Harrison R, (Der). Current Occupational & Environmental Medicine. Beşinci Edisyon. McGraw-Hill Education LLC, New York, 2014.
4. Rushton L, Hutchings SJ, Straif K. “Occupational Cancer Burden” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
5. Pott P. “Chirurgical observations : relative to the cataract, the polypus of the nose, the cancer of the scrotum, the different kinds of ruptures, and the mortification of the toes and feet” Londra, 1775.
6. Mustacchi P. “Ramazzini and Rigoni-Stern on parity and breast cancer. Clinical impression and statistical corroboration” Archives of internal medicine. 1961;108:639-42.
7. Lilienfeld DE. “The silence: the asbestos industry and early occupational cancer research—a case study” Am J Public Health. 1991;81(6):791-800.
8. Aksoy M, Erdem S, DinCol G. “Leukemia in shoe- workers exposed chronically to benzene” Blood. 1974;44(6):837-41.

9. Creech JL, Jr., Johnson MN. “Angiosarcoma of liver in the manufacture of polyvinyl chloride”. J Occup Med. 1974;16(3):150-1.
10. Kumar V, Abbas AK, Aster JC ve ark. “Neoplasia” İçinde: Kumar V, Abbas AK, Aster JC ve ark. (Der). Robbins Pathology. Dokuzuncu edisyon. 2015.
11. Langevin SM, Kelsey KT. “Mechanisms of Environmental and Occupational Carcinogenesis” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
12. Siemiatycki J. “Historical Overview of Occupational
13. mesleki risk faktörlerinin karsinojenik etkilerinin Cancer Research” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
14. IARC. “Agents Classified by the IARC Monographs Volumes 1–116” http://monographs.iarc. fr/ENG/Classification/index.php (09/08/2017)
15. Boffetta P. “Malignant Mesothelioma: Epidemiology” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
16. Roe OD, Stella GM. “Malignant pleural mesothelioma: history, controversy and future of a manmade epidemic” Eur Respir J. 2015;24(135):115-31.
17. IARC. “IARC List of classifications by cancer site” http://monographs.iarc.fr/ENG/Classification/ Table4.pdf (29/11/2016)
18. Attanoos RL. “Malignant Mesothelioma: Asbestos Exposure” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
19. Ferlay J, Soerjomataram I, Dikshit R ve ark. “Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012” Int J Cancer. 2015;136(5):E359-86.
20. Pavlisko EN, Boffetta P, Roggli VL. “Lung Cancer (Exposure Assessment, Pathology, and Epidemiology)” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
21. Weiderpass E, Labrèche F. “Malignant Tumors of the Female Reproductive System” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
22. IARC. “IARC Monographs on the evaluation of carcinogenic risks to humans, Painting, Firefighting, and Shiftwork, vol. 98” Lyon, 2010.
23. IARC. “IARC Monographs on the evaluation of carcinogenic risks to humans, Chemical Agents and Related Occupations, vol. 100F” Lyon, 2012.
24. Hill SM, Belancio VP, Dauchy RT ve ark. “Melatonin: an inhibitor of breast cancer” Endocrine- related cancer. 2015;22(3):R183-204.
25. Kogevinas M, Garcia-Closas M. “Bladder Cancer” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
26. Sim MR, Tan SSH, Nixon RL. “Malignant Neoplasms of the Skin” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
27. De Roos AJ, Bhatti P. “Lymphohematopoietic Malignancies” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
28. Filho VW. “Cancer of the Oral Cavity, Pharynx, and Nasopharynx” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
29. Husgafvel-Pursiainen K, Carton M, Luce D ve ark. “Sinonasal Cancer” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
30. Olsen FA. “Cancer of the larynx” İçinde: Schottenfeld D, Fraumeni J (Der). Cancer epidemiology and prevention. Üçüncü Edisyon. Oxford University Press, New York, 2006.
31. Boffetta P. “Laryngeal Cancer” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
32. Richiardi L, Zuccolo L. “Malignant Tumors of the Male Reproductive System” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
33. IARC. “IARC Monographs on the evaluation of carcinogenic risks to humans, Biological Agents, vol. 100B” Lyon, 2012.
34. Moore LE, Stewart PA, Karami S. “Kidney Cancer” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
35. Kuempel ED, Jaurand MC, Moller P ve ark. “Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans” Crit Rev Toxicol. 2016:1-58.
36. IARC. “IARC Monographs on the evaluation of carcinogenic risks to humans, Man-made Mineral Fibres and Radon, vol. 43” Lyon,1988.
37. IARC. “IARC Monographs on the evaluation of carcinogenic risks to humans, Man-made Vitreous Fibres, vol. 81” Lyon, 2002.
38. Gustavsson P. “Strategies for Primary Prevention of Occupational Cancer” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
39. Türkiye Halk Sağlığı Kurumu Kanser Daire Başkanlığı. “Kanser Taramaları” http://kanser.gov.tr/kanser/kanser-taramalari.html (10/10/2016)
40. Trout DB, Schulte PA, Tramma SL. “Screening for Occupational Cancer” İçinde: Anttila S, Boffetta P, (Der). Occupational Cancers. Springer Limited, Londra, 2014.
41. Wood DE, Eapen GA, Ettinger DS ve ark. “Lung cancer screening” JNCCN. 2012;10(2):240-65.l