Skin and mucosa in patients with solid organ transplant: risks and precautions

Abstract

In solid organ transplant patients; many skin diseases are more common and more resistant to treatment, because of the multiple medications and immunosuppressive therapies. In order to increase survival, it is important to evaluate and follow these patients with a multidisciplinary team including the dermatologist. In this review, the following are reviewed along with the current literature; skin and mucosa findings due to immunosuppressive therapies used in solid organ transplant patients, inflammatory, infectious and neoplastic skin diseases which are increased compared to the normal population, and the important points in diagnosis and treatment of these diseases.

Keywords

• immunosuppression
• Organ transplantation
• skin neoplasm
• drug reaction
• opportunistic infection
• infection prevention

Solid organ transplantasyonlu hastalarda deri ve mukoza: Riskler ve önlemler

Abstract

Solid organ nakli hastalarının kullandığı çoklu ilaçlar ve immünsupresif tedaviler nedeniyle birçok deri hastalığı bu hasta grubunda daha sık görülmekte ve tedaviye daha dirençli seyretmektedir. Hastaların, sağ kalımlarını arttırmak amacı ile içerisinde dermatoloji uzmanının da bulunduğu bir ekip tarafından multidisipliner olarak değerlendirilmesi ve takip edilmesi önemlidir. Bu derlemede solid organ nakli hastalarında kullanılan immünsupresif tedavilere bağlı görülen deri ve mukoza bulguları, topluma göre sıklığında artış gözlenen enflamatuar, enfeksiyöz ve neoplastik deri hastalıkları ile bu hastalıkların tanı ve tedavisinde dikkat edilmesi gereken noktalar güncel literatür eşliğinde gözden geçirilmiştir.

Keywords

• organ nakli
• immünsupresyon
• deri kanserleri
• ilaç reaksiyonları
• fırsatçı enfeksiyonlar
• enfeksiyon önlemleri

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