Different mucosal presentations of non-Hodgkin lymphoma: case series

Year 2020, Volume: 3 Issue: 3, 69 - 74, 30.09.2020

Ayşenur Bahadır Murat Çakır Elif Sağ Gökçe Pınar Reis İlker Eyüpoğlu Erol Erduran Osman Bahadır

https://doi.org/10.33204/mucosa.774141

Abstract

Non-Hodgkin lymphoma has an incidence 8% of all childhood malignancies in the world. Non-Hodgkin lymphoma typically invades the liver, lungs, spleen and mediastinum. The most common symptoms include pain and coughing due to enlarged lymph nodes, shortness of breath due to thoracic masses, and bowel obstruction and acid in abdominal involvement. In this study, we have discussed cases of lymphoma with different mucosal presentations. The age of the patients varied from 3.5-16 years, and included three females and two males. The cases include patients with lymphoblastic lymphoma referring with a preliminary diagnosis of eosinophilic granuloma; with lymphoblastic lymphoma, with a preliminary diagnosis of odontogenic cyst; with Burkitt lymphoma, with lower gastrointestinal system bleeding-acute gastroenteritis; with Burkitt lymphoma, with a preliminary diagnosis of ovarian tumor and with diffuse large B-cell lymphoma, with a diagnosis of anemia. Clinical, laboratory and radiological diagnostic methods can guide diagnosis of lymphoma, histopathologic examination is important for the final diagnosis. In conclusion, it is important to make a systemic evaluation rather than focusing only on the referral complaints and radiological imaging in patient assessment.

Keywords

lymphoma, bone, ovarian, gastrointestinal system, child

Non-Hodgkin lenfomanın farkı mukozal görünümleri: Olgu serisi

Abstract

Dünyada çocukluk çağı malinitelerinin %8’ini non-hodgkin lenfoma oluşturmaktadır. Non-hodgkin lenfoma genellikle karaciğer, akciğer, dalak ve mediastinuma yayılır. En yaygın bulgusu lenf nodu genişlemesine bağlı ağrı,
öksürük, torakstaki kitlelere bağlı nefes darlığı, abdominal bölge tutulumunda barsak obstrüksiyonu ve asit gibi
bulgulardır. Biz burada farklı klinik ve radyolojik bulgularla gelip, lenfoma tanısı koyduğumuz hastalarımızı
tartıştık. Hastaların yaşları 3,5-16 yıl arasında olup üç kız, iki erkekti. Eozinofilik granülom ön tanısı ile gelen
lenfoblastik lenfoma, odontojenik kist ön tanısı ile gelen lenfoblastik lenfoma, alt gis kanama-akut gastroenterit şikayeti ile gelen Burkitt lenfoma, over tümörü tanısı ile gelen Burkitt lenfoma, anemi tanısı ile gelen diffüz
büyük hücreli B-cell lenfoma tanılı olgularımızı rapor ettik. Lenfomanın tanısında klinik, laboratuvar ve radyolojik
tanı yöntemleri yol gösterici olsa da patolojik doku tanısı kesin tanı için önemlidir. Hastalar değerlendirilirken
sadece başvuru şikayetine, radyolojik görüntülemelere odaklanmayıp, sistemik odaklanılmamalı,
sistemik olarak değerlendirme yapılmalıdır.

Keywords

çocuk, lenfoma, kemik, over, gastrointestinal sistem

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