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Laugier-Hunziker sendromu: Nadir bir olgu sunumu ve literatürün gözden geçirilmesi

Year 2021, Volume: 4 Issue: 2, 50 - 55, 30.06.2021
https://doi.org/10.33204/mucosa.948546

Abstract

Laugier-Hunziker sendromu, mukokutanöz lentijinler ve melanonişiyle seyreden nadir görülen kalıtsal bir pigment bozukluğudur. Bu sendroma, altta yatan bir malignite ya da sistemik hastalıkla henüz ilişkilendirilmediğinden benign olarak yaklaşılır. Peutz-Jeghers, Cronkhite-Canada sendromu gibi malignite sendromları ve Addison hastalığı, ilaçlar gibi hiperpigmentasyona yol açan durumlar da benzer mukokutanöz bulgularla seyrettiğinden, hastaların bu durumlar dışlanarak değerlendirilmesi önemlidir.

References

  • Laugier P, Hunziker N. Essential lenticular melanic pigmentation of the lip and cheek mucosa. Arch Belg Dermatol Syphiligr 1970;26:391-9.
  • Sardana K, Mishra D, Garg V. Laugier Hunziker syndrome. Indian Pediatr 2006;43:998-1000.
  • Panchami Deb Barman AD, Ashim KM, Piyush K. Laugier-Hunziker syndrome revisited. Indian J Dermatol 2016;61:338-9.
  • Kacar N, Yildiz CC, Demirkan N. Dermoscopic features of conjunctival, mucosal, and nail pigmentations in a case of Laugier-Hunziker syndrome. Dermatol Pract Concept 2016;6:23-4.
  • Makhoul EN, Ayoub NM, Helou JF, Abadjian GA. Familial Laugier-Hunziker syndrome. J Am Acad Dermatol 2003;49:143-5.
  • Lee JS, Park KC, Shin JW, Huh CH, Na JI. Two cases of Laugier-Hunziker syndrome with thrombocytopenia. Eur J Dermatol 2018;28:830-1.
  • Enginar A, Karaman NS, Karakas AA. Laugier-Hunziker syndrome in a patient with rheumatoid arthritis. Reumatologia 2019;57:63-5.
  • Duan N, Zhang YH, Wang WM, Wang X. Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome. World J Clin Cases 2018;6:322-34.
  • Baran R. Longitudinal melanotic streaks as a clue to Laugier-Hunziker syndrome. Arch Dermatol 1979;115:1448-9.
  • Nair V. Laugier-Hunziker syndrome: complete clearance of mucosal lentigines with a single session of Q-Switched Nd:YAG laser. J Cosmet Laser Ther 2019;21:343-5.

Laugier-Hunziker syndrome: a rare case report and review of the literature

Year 2021, Volume: 4 Issue: 2, 50 - 55, 30.06.2021
https://doi.org/10.33204/mucosa.948546

Abstract

Laugier-Hunziker syndrome is a rare, hereditary pigmentary disorder characterized by mucocutaneous lentiginous lesions and melanonychia. The condition is regarded as benign since underlying malignancies or systemic disorders were not reported. Since various malignancy syndromes including Peutz-Jeghers and Cronkhite-Canada syndrome and systemic cause of hyperpigmentation such as Addison disease and drugs are presented with similar mucocutaneous findings, it is of paramount importance to assess the patients to exclude aforementioned conditions.

References

  • Laugier P, Hunziker N. Essential lenticular melanic pigmentation of the lip and cheek mucosa. Arch Belg Dermatol Syphiligr 1970;26:391-9.
  • Sardana K, Mishra D, Garg V. Laugier Hunziker syndrome. Indian Pediatr 2006;43:998-1000.
  • Panchami Deb Barman AD, Ashim KM, Piyush K. Laugier-Hunziker syndrome revisited. Indian J Dermatol 2016;61:338-9.
  • Kacar N, Yildiz CC, Demirkan N. Dermoscopic features of conjunctival, mucosal, and nail pigmentations in a case of Laugier-Hunziker syndrome. Dermatol Pract Concept 2016;6:23-4.
  • Makhoul EN, Ayoub NM, Helou JF, Abadjian GA. Familial Laugier-Hunziker syndrome. J Am Acad Dermatol 2003;49:143-5.
  • Lee JS, Park KC, Shin JW, Huh CH, Na JI. Two cases of Laugier-Hunziker syndrome with thrombocytopenia. Eur J Dermatol 2018;28:830-1.
  • Enginar A, Karaman NS, Karakas AA. Laugier-Hunziker syndrome in a patient with rheumatoid arthritis. Reumatologia 2019;57:63-5.
  • Duan N, Zhang YH, Wang WM, Wang X. Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier-Hunziker syndrome. World J Clin Cases 2018;6:322-34.
  • Baran R. Longitudinal melanotic streaks as a clue to Laugier-Hunziker syndrome. Arch Dermatol 1979;115:1448-9.
  • Nair V. Laugier-Hunziker syndrome: complete clearance of mucosal lentigines with a single session of Q-Switched Nd:YAG laser. J Cosmet Laser Ther 2019;21:343-5.
There are 10 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Case Reports
Authors

Hande Ermiş 0000-0002-1431-2203

Publication Date June 30, 2021
Published in Issue Year 2021 Volume: 4 Issue: 2

Cite

Vancouver Ermiş H. Laugier-Hunziker syndrome: a rare case report and review of the literature. Mucosa. 2021;4(2):50-5.