HEALTH RISK ASSESSMENT OF ARSENIC CONTAMINATION FROM THE CONSUMPTION OF COMMERCIALLY IMPORTANT EUROPEAN SEA BASS (Dicentrarchus labrax L., 1758)

Year 2022, Volume: 8 Issue: 1, 51 - 62, 28.06.2022

Aykut Yozukmaz , Murat Yabanlı

https://doi.org/10.22531/muglajsci.1001878

Abstract

Sea bass (Dicentrarchus labrax L., 1758) production in Turkey has increased significantly in recent years, especially for export to EU countries. This study determined inorganic arsenic (iAs) levels by measuring total arsenic levels (AsT) in muscle tissues sampled from sea bass fished and farmed (both in earthen ponds and sea cages) in Güllük Bay within the borders of Muğla province. The study also conducted a risk assessment of sea bass consumption for consumer health. For this aim, fish muscle tissues were mineralized with microwave digestion before total arsenic concentrations were measured using inductively coupled plasma mass spectroscopy (ICP-MS). The highest mean arsenic levels were detected in sea bass cultured in earthen ponds (0.38 mg kg^-1) while levels in both sea bass cultured off-shore and wild sea bass were 0.26 mg kg^-1. According to the risk assessments based on estimated daily intake (EDI), target hazard quotient (THQ), carcinogenic risk (CR), and lifetime cancer risk (TR), it was revealed that eating sea bass did not damage human health.

Keywords

Arsenic, consumer health, Dicentrarchus labrax, risk assessment.

References

• Balcı Akova, S., “Aquaculture and Its Distribution in Turkey”, Journal of Aquaculture Engineering and Fisheries Research, 1(4), 160–190, doi: 10.3153/JAEFR15018, 2015.
• Çakmak, E., Aksungur, N., Firidin, Ş., Aksungur, M., Çavdar, Y., Kurtoğlu, İ.Z., Başçınar, N.S., Akbulut, B., Savaş, H., Üstündağ, E., Alkan, A., Ergün, H., Ertekin, A., Zengin, B., Serdar, S., Fidan, D. ve Özkan, B., “Karadeniz Alabalığı (Salmo trutta labrax Pallas, 1811)’nın Özel Sektöre Kazandırılması, Proje Sonuç Raporu Kitabı” TAGEM/HAYSÜD/2006/ 09/03/02, Trabzon, 147 s, 2011.
• Alparslan, Y, and Baygar, T., "Levrek balığının Türkiye ve Dünyada yeri, önemi ve pazar durumu." Anadolu Bil Meslek Yüksekokulu Dergisi, 13: 31-40, 2009.
• FAO, “The State of World Fisheries and Aquaculture 2020. Sustaninability in action” ,Rome, 244 pp., doi 10.4060/ca9229en, 2020.
• Yucel-Gier, G., Uslu, O, and Kucuksezgin, F., “Regulating and monitoring marine finfish aquaculture in Turkey”, Journal of Applied Ichthyology, 25(6), 686–694, doi: 10.1111/j.1439-0426.2009.01367.x, 2009.
• Rana, K.J., “Regional review on aquaculture development.” 6. Western European region 2005, Food & Agriculture Org., 2007.
• TURKSTAT, “Fishery Statistics Prime Ministry Republic of Turkey Turkish Statistical Institute Fishery Statistics”, http://w/ww.turkstat.gov.tr, 2020, (Accessed on 25 Feb 2021).
• FEAP, “Annual report 2020”, FEAP Aquac Liege, Belgium, 2020.
• Clarke, R. and Bostock, J., “Regional Review on Status and Trends in Aquaculture Development in Europe – 2015”, Food & Agricultural Organization of the United Nations. FAO Fisheries and Aquaculture Circular, 1135/1, 2017.
• TURKSTAT, “Fishery Statistics Prime Ministry Republic of Turkey Turkish Statistical Institute Fishery Statistics”, 2016, http://w/ww.turkstat.gov.tr/PreTablo.do?alt_id=1005, (Accessed on 13 Feb 2018).
• Bosch, A.C., O'Neill, B., Sigge, G.O., Kerwath, S.E. and Hoffman, L. C., “Heavy metals in marine fish meat and consumer health: a review”, Journal of the Science of Food and Agriculture, 96(1), 32-48, 2016.
• Yilmaz, A.B. and Yilmaz, L., “Influences of sex and seasons on levels of heavy metals in tissues of green tiger shrimp (Penaeus semisulcatus de Hann, 1844)”, Food Chemistry, 101(4), 1664–1669, doi: 10.1016/j.foodchem.2006.04.025, 2007.
• Järup, L., “Hazards of heavy metal contamination”, British Medical Bulletin, 68(1), 167–182, doi: 10.1093/bmb/ldg032, 2003.
• USEPA, “Supplemental Guidance for Developing Soil Screening Office of Emergency and Remedial Response,” 4–24, 2002.
• Ng, J.C, Wang, J. and Shraim, A., “A global health problem caused by arsenic from natural sources”, Chemosphere, 52(9), 1353–1359, doi: 10.1016/S0045-6535(03)00470-3, 2003.
• Mandal, B.K and Suzuki, K.T., “Arsenic round the world: A review”, Talanta, 58(1), 201–235, doi: 10.1016/S0039-9140(02)00268-0, 2002.
• Van Scoy, A.R, Yue, M., Deng, X. and Tjeerdema, R.S., “Environmental fate and toxicology of methomyl”, Reviews of Environmental Contamination and Toxicology, 93-109, 2013.
• Azcue, J.M. and Nriagu, J.O., “Arsenic: Historical perspectives in arsenic in the environment, Part 1: cycling and characterization”, 448, 1994.
• International Agency for Research on Cancer, “IARC monographs on the evaluation of carcinogenic risk of chemicals to man”, IARC monographs on the evaluation of carcinogenic risk of chemicals to man, 1, 184, 1972.
• Bissen, M. and Frimmel, F.H., “Arsenic - A review. Part I: Occurrence, toxicity, speciation, mobility”, Acta Hydrochimica et Hydrobiologica, 31(1), 9–18. doi: 10.1002/aheh.200390025, 2003.
• Abernathy, C.O., Liu, Y.P., Longfellow, D., Aposhian, H.V., Beck, B., Fowler, B., Goyer, R., Menzer, R., Rossman, T., Thompson, C. and Waalkes, M., “Arsenic: health effects, mechanisms of actions, and research issues”, Environmental Health Perspectives, 107(7), 593–7, doi: 10.1289/ehp.99107593, 1999.
• National Research Council, “Arsenic in drinking water: 2001 update.” The National Academies Press, Washington, DC., 2001.
• Chen, Y., Parvez, F., Gamble, M., Islam, T., Ahmed, A., Argos, M., Graziano, J.H. and Ahsan, H., “Arsenic exposure at low-to-moderate levels and skin lesions, arsenic metabolism, neurological functions, and biomarkers for respiratory and cardiovascular diseases: Review of recent findings from the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh”, Toxicology and Applied Pharmacology, 239(2), 184–192, doi: 10.1016/j.taap.2009.01.010, 2009.
• Lubin, J.H, Beane Freeman L.E. and Cantor, K.P., “Inorganic arsenic in drinking water: An evolving public health concern”, Journal of the National Cancer Institute, 99, 906–907, doi: 10.1093/jnci/djm012, 2007.
• Smith, A.H. and Steinmaus, C.M., “Health Effects of Arsenic and Chromium in Drinking Water: Recent Human Findings”, Annual Review of Public Health, 30, 107–122, doi: 10.1146/annurev.publhealth.031308.100143, 2009.
• Rose, M., Lewis, J., Langford, N., Baxter, M., Origgi, S., Barber, M., MacBain, H. and Thomas, K., “Arsenic in seaweed-Forms, concentration and dietary exposure”, Food and Chemical Toxicology, 45(7), 1263–1267, doi: 10.1016/j.fct.2007.01.007, 2007.
• Burger, J., Fossi, C., McClellan-Green, P. and Orlando, E.F., “Methodologies, bioindicators, and biomarkers for assessing gender-related differences in wildlife exposed to environmental chemicals”, Environmental Research, 104(1), 135–152, doi: 10.1016/j.envres.2006.08.002, 2007.
• EFSA., “Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the commission related to arsenic as undesirable substance in animal feed”, EFSA Journal, 180, 1–35, 2005.
• FAO, “The State of World Fisheries and Aquaculture”, Rome, 2014.
• Copat, C., Arena, G., Fiore, M., Ledda, C., Fallico, R., Sciacca, S. and Ferrante, M., “Heavy metals concentrations in fish and shellfish from eastern Mediterranean Sea: Consumption advisories”, Food and Chemical Toxicology, 53, 33–37, doi: 10.1016/j.fct.2012.11.038, 2013.
• Storelli, M.M. and Barone, G., “Toxic Metals (Hg, Pb, and Cd) in Commercially Important Demersal Fish from Mediterranean Sea: Contamination Levels and Dietary Exposure Assessment”, Journal of Food Science, 78(2), T362-T366, doi: 10.1111/j.1750-3841.2012.02976.x, 2013.
• Barone, G., Storelli, A., Garofalo, R., Busco, V.P., Quaglia, N.C., Centrone, G. and Storelli, M.M., “Assessment of mercury and cadmium via seafood consumption in Italy: estimated dietary intake (EWI) and target hazard quotient (THQ)”, Food Additives & Contaminants - Part A, 32(8), 1277–1286, doi: 10.1080/19440049.2015.1055594, 2015.
• Petroczi, A. and Naughton, D.P., “Mercury, cadmium and lead contamination in seafood: A comparative study to evaluate the usefulness of Target Hazard Quotients”, Food and Chemical Toxicology, 47(2), 298–302, doi: 10.1016/j.fct.2008.11.007, 2009.
• USEPA, “Integrated Risk Information System”, https://w/ww.epa.gov/iris, 2018, (Accessed on 9 Mar 2018).
• Şaşi, H., Yozukmaz, A. and Yabanli, M., “Heavy metal contamination in the muscle of Aegean chub (Squalius Fellowesii) and potential risk assessment”, Environmental Science and Pollution Research, 25(7), 1–9. doi: 10.1007/s11356-017-1030-y, 2017.
• Yucel-Gier, G., İdil, P. A. Z. İ. and Kucuksezgin, F., “Spatial analysis of fish farming in the Gulluk Bay (Eastern Aegean)”, Turkish Journal of Fisheries and Aquatic Sciences, 13(4), 2013.
• Ashoka, S., Peake, B.M., Bremner, G., Hageman, K.J. and Reid, M.R., “Comparison of digestion methods for ICP-MS determination of trace elements in fish tissues”, Analytica Chimica Acta, 653(2), 191–199, doi: 10.1016/j.aca.2009.09.025, 2009.
• Matek, M. and Blannusa, M., “Comparison of two methods for destruction of biological material for determination of selenium”, Arhiv za higijenu rada i toksikologiju, 49(4), 301–305, 1998.
• Nkpaa, K.W, Patrick-Iwuanyanwu, K.C, Wegwu, M.O. and Essien, E.B., “Health risk assessment of hazardous metals for population via consumption of seafood from Ogoniland, Rivers State, Nigeria; a case study of Kaa, B-Dere, and Bodo City”, Environmental Monitoring and Assessment, 188(1), 1-10, doi: 10.1007/s10661-015-5006-4, 2016.
• Kalantzi, I., Pergantis, S.A., Black, K.D., Shimmield, T.M., Papageorgiou, N., Tsapakis, M. and Karakassis, I., “Metals in tissues of seabass and seabream reared in sites with oxic and anoxic substrata and risk assessment for consumers”, Food Chemistry, 194, 659–670, doi: 10.1016/j.foodchem.2015.08.072, 2016.
• Varol, M., Kaya, G.K. and Alp, A., “Heavy metal and arsenic concentrations in rainbow trout (Oncorhynchus mykiss) farmed in a dam reservoir on the Firat (Euphrates) River: Risk-based consumption advisories”, Science of the Total Environment, 599, 1288–1296, doi: 10.1016/j.scitotenv.2017.05.052, 2017.
• Norin, H., Christakopoulos, A., Sandström, M. and Ryhage, R., “Mass fragmentographic estimation of trimethylarsine oxide in aquatic organisms”, Chemosphere, 14(3-4), 313–323, doi: 10.1016/0045-6535(85)90059-1, 1985.
• Roychowdhury, T., Uchino, T., Tokunaga, H. and Ando, M., “Survey of arsenic in food composites from an arsenic-affected area of West Bengal, India”, Food and Chemical Toxicology, 40(11), 1611–1621, doi: 10.1016/S0278-6915(02)00104-7, 2002.
• Borak, J. and Hosgood, H.D., “Seafood arsenic: Implications for human risk assessment”, Regulatory Toxicology and Pharmacology, 47(2), 204–212, doi: 10.1016/j.yrtph.2006.09.005, 2007.
• Li, Y., Liu, H., Zhou, H., Ma, W., Han, Q., Diao, X. and Xue, Q., “Concentration distribution and potential health risk of heavy metals in Mactra veneriformis from Bohai Bay, China”, Marine Pollution Bulletin, 97(1-2), 528–534, doi: 10.1016/j.marpolbul.2015.05.017, 2015.
• Sofuoglu, S.C. and Kavcar, P., “An exposure and risk assessment for fluoride and trace metals in black tea”, Journal of Hazardous Materials, 158(2-3), 392–400, doi: 10.1016/j.jhazmat.2008.01.086, 2008.
• Copat, C., Bella, F., Castaing, M., Fallico, R., Sciacca, S. and Ferrante, M., “Heavy metals concentrations in fish from Sicily (Mediterranean Sea) and evaluation of possible health risks to consumers”, Bulletin of Environmental Contamination and Toxicology, 88(1), 78–83, doi: 10.1007/s00128-011-0433-6, 2012.
• Brodberg, R. and Klasing, S., “Evaluation of potential health effects of eating fish from Black Butte reservoir (Glenn and Tehama Counties): guidelines for sport fish consumption”, Pesticide and Environmental Toxicology Section Office of Environmental Protection Agency, California, 2003.
• Yaman, M., Karaaslan, N.M. and Yaman, I.H., “Seasonal Variations in Toxic Metal Levels of Two Fish Species, Mugil cephalus and Mullus barbatus and Estimation of Risk for Children”, Bulletin of Environmental Contamination and Toxicology, 93(3), 344–349, doi: 10.1007/s00128-014-1342-2, 2014.
• GDFA, “Republic of Turkey Ministry of Food and Livestock General Directorate of Fisheries and Aquaculture”, In: Gıda Tarım ve Hayvancılık Bakanlığı, https://w/ww.tarim.gov.tr/sgb/Belgeler/SagMenuVeriler/BSGM.pdf, 2017, (Accessed 12 Mar 2018).
• Liu, C.W., Liang, C.P., Huang, F.M. and Hsueh, Y.M., “Assessing the human health risks from exposure of inorganic arsenic through oyster (Crassostrea gigas) consumption in Taiwan”, Science of the Total Environment, 361(1-3), 57–66, doi: 10.1016/j.scitotenv.2005.06.005, 2006.
• Yi, Y., Yang, Z. and Zhang, S., “Ecological risk assessment of heavy metals in sediment and human health risk assessment of heavy metals in fishes in the middle and lower reaches of the Yangtze River basin”, Environmental Pollution, 159(10), 2575–2585, doi: 10.1016/j.envpol.2011.06.011, 2011.
• Khan, S., Farooq, R., Shahbaz, S., Khan, M.A. and Sadique, M., “Health Risk Assessment of Heavy Metals for Population via Consumption of Vegetables”, World Applied Sciences Journal, 6(12), 1602–1606, doi: 10.14737/journal.aavs/2015/3.1.58.70, 2009.
• Harmanescu, M., Alda, L.M., Bordean, D.M., Gogoasa, I. and Gergen, I., “Heavy metals health risk assessment for population via consumption of vegetables grown in old mining area; a case study: Banat County, Romania”, Chemistry Central Journal, 5(1), 1-10, doi: 10.1186/1752-153X-5-64, 2011.
• USEPA, “Risk-based concentration table”, Philadelphia PA: United States Environmental Protection Agency, Washington DC., 2000.
• USEPA, “Assessing Human Health Risks from Chemically Contaminated Fish and Shellfish. EPA-503/8-89-002”, US Environmental Protection Agency, Washington, DC., 1989.
• Molina, V.B., “Health Risk Assessment of Selected Heavy Metals Bioaccumulation in Laguna de Bay [Philippines] fish products”, 14th World Lake Conference, 1–23, 2011.
• USEPA, “Guidelines for Ecological Risk Assessment. EPA/630/R-95/002F”, 63:26846–26924, 1998.
• USEPA, “Regional screening levels for chemical contaminants at superfund sites”, http//w/ww.epa.gov/reg3hwmd/risk/human/rb-concentration_table/usersguide.htm, 2011.
• Walsh, P.J., Smith, S., Fleming, L., Solo-Gabriele, H. and Gerwick, W.H., (eds.), Oceans and Human Health: Risks and Remedies from the Seas, Academic Press, 2011.
• USEPA, “Special report on ingested inorganic arsenic: Skin cancer; nutritional essentiality. EPA/625/3-87/013”, US Environmental Protection Agency, Risk Assessment Forum, Washington, DC., 1988.
• USEPA, “Risk-based concentration table, Region 3”, US Environmental Protection Agency, Philadelphia, PA., 2006.
• Mansilla-Rivera, I. and Rodríguez-Sierra, C.J., “Metal levels in fish captured in Puerto Rico and estimation of risk from fish consumption”, Archives of Environmental Contamination and Toxicology, 60(1), 132–144, doi: 10.1007/s00244-010-9538-x, 2011.
• Agency for Toxic Substances and Disease Registry, “Toxicological profile information sheet”, https://w/ww.atsdr.cdc.gov/toxprofiles/index.asp#I, 2010, (Accessed on 7 Mar 2018).
• USEPA, “Toxicological review of inorganic arsenic. Draft document. EPA/635/R-10/001”, Washington, DC, USA., 2010.
• WHO, “Evaluation of certain food additives and contaminants. WHO Technical Report Series, Number 837”, World Health Organization, Geneva, 1993.
• Walsh, L. M., Sumner, M. E. and Keeney, D.R., “Occurrence and distribution of arsenic in soils and plants”, Environmental Health Perspectives, 19, 67–71, doi: 10.1289/ehp.771967, 1977.
• Robinson, G.R. and Ayuso, R.A., “Use of spatial statistics and isotopic tracers to measure the influence of arsenical pesticide use on stream sediment chemistry in New England, USA”, Applied Geochemistry, 19(7), 1097–1110, doi: 10.1016/j.apgeochem.2004.01.009, 2004.
• Murphy, E.A. and Aucott, M., “An assessment of the amounts of arsenical pesticides used historically in a geographical area”, Science of the Total Environment, 218(2-3), 89–101, doi: 10.1016/S0048-9697(98)00180-6, 1998.
• Peryea, F.J., “Evaluation of five soil tests for predicting responses of apple trees planted in lead arsenate-contaminated soil”, Communications in Soil Science and Plant Analysis, 33(1-2), 243–257, doi: 10.1081/CSS-120002391, 2002.
• Renshaw, C.E., Bostick, B.C., Feng, X., Wong, C.K., Winston, E.S., Karimi, R., Folt, C.L. and Chen, C.Y., “Impact of land disturbance on the fate of arsenical pesticides”, Journal of Environmental Quality, 35(1), 61–67, doi: 10.2134/jeq2005.0096, 2006.
• Fordyce, J.S. and Sheibley, D.W., “Estimate of Contribution of Jet Aircraft Operations to Trace Element Concentration at or near Airports”, Journal of the Air Pollution Control Association, 25(7), 721–724, doi: 10.1080/00022470.1975.10470131, 1975.
• Illinois Environmental Protection Agency, “Final Report Chicago O’ Hare Airport Air Toxic Monitoring Program June – December, 2000”, http://w/ww.epa.state.il.us/air/ohare, 2002.
• Makedonski, L., Peycheva, K., & Stancheva, M., “Comparison of heavy metal concentration of some marine fishes from Black and Aegean Seas”, Ovidius University Annals of Chemistry, 26(1), 20-26, doi: 10.1515/auoc-2015-0004, 2015.
• Žvab Rožič, P., Dolenec, T., Baždarić, B., Karamarko, V., Kniewald, G., & Dolenec, M., “Element levels in cultured and wild sea bass (Dicentrarchus labrax) and gilthead sea bream (Sparus aurata) from the Adriatic Sea and potential risk assessment”, Environmental geochemistry and health, 36(1), 19-39, doi:10.1007/s10653-013-9516-0, 2014.
• Kocatepe, D., & Turan, H., “Chemical composition of cultured sea bass (Dicentrarchus labrax, Linnaeus 1758) muscle”, Journal of Food & Nutrition Research, 51(1), 33-39, 2012.
• Varol, M., Kaya, G. K., & Sünbül, M. R., “Evaluation of health risks from exposure to arsenic and heavy metals through consumption of ten fish species”, Environmental Science and Pollution Research, 26(32), 33311-33320, doi: 10.1007/s11356-019-06450-x, 2019.
• Bat, L., Şahin, F., Bhuyan, M., Arici, E., & Öztekin, A., “Metals in Wild and Cultured Dicentrarchus labrax (Linnaeus, 1758) from Fish Markets in Sinop: Consumer’s Health Risk Assessment”, Biological Trace Element Research, 1-9, doi: 10.1007/s12011-021-03064-8, 2022.
• Yabanli, M., Tay, S., & Giannetto, D., “Human health risk assessment from arsenic exposure after sea bream (Sparus aurata) consumption in Aegean Region, Turkey”, Bulgarian Journal of Veterinary Medicine, 19(2), 127-136, doi: : 10.15547/bjvm.905, 2016.
• Ozkan, O. and Nuray, E., “Evaluation of Risk Characterization for Mercury, Cadmium, Lead and Arsenic Associated with Seafood Consumption in Turkey”, Exposure and Health, 8(1), 43–52, doi: 10.1007/s12403-015-0181-7, 2016.
• JECFA, “Evaluations of the Joint FAO/WHO Expert Committee on Food Additives”, http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=1863, 2009, (Accessed on 7 Mar 2018).
• New York State Department of Health, “Hopewell precision area contamination: Appendix C-NYS DOH”, In: Procedure for evaluating potential health risks for contaminants of concern, 2007.
• Javed, M. and Usmani, N., “Accumulation of heavy metals and human health risk assessment via the consumption of freshwater fish Mastacembelus armatus inhabiting, thermal power plant effluent loaded canal”, Springerplus, 5 (1), 776. https://doi.org/10.1186/s40064-016-2471-3. doi: 10.1186/s40064-016-2471-3, 2016.
• JECFA/WHO, “Evaluation of certain food additives and contaminants, Twenthy-seventh Report of the joint FAO/WHO Expert Commitee on Food Additives”, Technical Report Series, 696, 1983.
• Onsanit, S., Ke, C., Wang, X., Wang, K.J. and Wang, W.X., “Trace elements in two marine fish cultured in fish cages in Fujian province, China”, Environmental Pollution, 158(5), 1334–1342, doi: 10.1016/j.envpol.2010.01.012, 2010.
• Wang, H.S., Sthiannopkao, S., Chen, Z.J., Man, Y.B., Du, J., Xing, G.H., Kim, K.W., Yasin, M.S.M., Hashim, J.H. and Wong, M.H., “Arsenic concentration in rice, fish, meat and vegetables in Cambodia: A preliminary risk assessment”, Environmental Geochemistry and Health, 35(6), 745–755, doi: 10.1007/s10653-013-9532-0, 2013.
• Valberg, P.A., Drivas, P.J., McCarthy, S. and Watson, A.Y., “Evaluating the health impacts of incinerator emissions”, Journal of Hazardous Materials, 47(1-3), 205–227, doi: 10.1016/0304-3894(96)82225-4, 1996.
• Han, B.C., Jeng, W.L., Chen, R.Y., Fang, G.T., Hung, T.C. and Tseng, R.J., “Estimation of target hazard quotients and potential health risks for metals by consumption of seafood in Taiwan”, Archives of Environmental Contamination and Toxicology, 35(4), 711–720, doi: 10.1007/s002449900535, 1998.
• Saha, N. and Zaman, M.R., “Evaluation of possible health risks of heavy metals by consumption of foodstuffs available in the central market of Rajshahi City, Bangladesh”, Environmental Monitoring and Assessment, 185(5), 3867–3878, doi: 10.1007/s10661-012-2835-2, 2013.
• Ramon, D., Morick, D., Croot, P., Berzak, R., Scheinin, A., Tchernov, D., Davidovich, N. and Britzi, M., “A survey of arsenic, mercury, cadmium, and lead residues in seafood (fish, crustaceans, and cephalopods) from the south‐eastern Mediterranean Sea”, Journal of Food Science, 86(3), 1153-1161. doi: 10.1111/1750-3841.15627, 2021.
• Vieira, C., Morais, S., Ramos, S., Delerue-Matos, C. and Oliveira, M.B.P.P., “Mercury, cadmium, lead and arsenic levels in three pelagic fish species from the Atlantic Ocean: Intra- and inter-specific variability and human health risks for consumption”, Food and Chemical Toxicology, 49(4), 923–932, doi: 10.1016/j.fct.2010.12.016, 2011.
• Yilmaz, A.B., Sangun, M.K., Yaglioglu, D. and Turan, C., “Metals (major, essential to non-essential) composition of the different tissues of three demersal fish species from İskenderun Bay, Turkey”, Food Chemistry, 123(2), 410–415, doi: 10.1016/j.foodchem.2010.04.057, 2010.
• Soto-Jimenez, M.F., Amezcua, F. and Gonzalez-Ledesma, R., “Nonessential metals in striped marlin and indo-pacific sailfish in the Southeast Gulf of California, Mexico: Concentration and assessment of human health risk”, Archives of Environmental Contamination and Toxicology, 58(3), 810–818, doi: 10.1007/s00244-009-9452-2, 2010.