Assessment of Vitamin D3 and Selected Interleukins in Atherosclerosis Patients and Their Association with Various Biochemical Markers in Salah al-Din Governorate

Year 2025, Volume: 10 Issue: 2, 563 - 574, 01.09.2025

May Khalil Ghaffar , Iktifaa Abdul Hamid Mohammed Saeed

https://doi.org/10.28978/nesciences.1759496

Abstract

This research seeks to assess vitamin D3 and several interleukins in relation to atherosclerosis and their correlation with many biochemical markers. This work sampled (180) men aged (45-75) years with atherosclerosis. The sampled is grouped into five: the initial group comprised of 40 individuals with chronic atherosclerosis; the second group included 40 individuals with acute atherosclerosis; the third group consisted of 40 individuals with atherosclerosis and diabetes; the fourth group contained 35 individuals with atherosclerosis receiving vitamin D; and the fifth group comprised 25 healthy individuals without any disease, serving as the control group. The research was conducted at Salah al-Din General Hospital in Salah al-Din Governorate, including patients admitted to the critical care unit and those in specialized clinics in Tikrit, after a meticulous diagnosis by expert physicians based on clinical manifestations. The level of (P≤0.05) of Vitamin D3 significantly rose for the group of with atherosclerosis taking Vitamin D3, while significantly dropped at the level of (P≤0.01) for the study groups, while the level of (P≤0.05), (P≤0.01) in IL-1, IL-6, IL-8, CD4 and CD8 significantly rose. In this study, *Distinct letters arranged horizontally indicate substantially different levels at (P ≤ 0.05) and (P ≤ 0.01).

Keywords

Vitamin D3 , Atherosclerosis , Interleukins , Biochemical Indicators

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