Investigation of the Effect of Ankaferd Blood Stopper on Wound Healing of Donor Site

Year 2023, Volume: 5 Issue: 2, 75 - 82, 28.08.2023

Ahmet Cemil Talmaç Dicle Altındal Metin Çalışır Bilal Ege

Abstract

Aim: The aim of this study is to evaluate the effect of Ankaferd Blood Stopper (ABS) on the palatal donor site following free gingival graft (FGG) surgery.
Materials and Methods: A total of 12 patients (24 palatal sites) were included in the study. In each patient, the donor sites were randomly divided into two groups. ABS+collagen pad was applied to test group. Only collagen pad was applied to control group. Donor sites were evaluated in terms of bleeding, epithelialization, sensitivity, pain score, analgesic usage, wound size, wound healing (LTH) index, and tissue thickness (TT).
Results: Intraoperative bleeding was observed in significantly more patients (n=9) in the control group, while it was not observed in any of the patients in the test group (p=0.000). Although higher epithelialization (33.3%) was detected in the test group on day 14th, there was no significant difference in epithelization between the groups. There was no significant difference in pain score, analgesic usage, wound size, LTH index, and TT between the groups. When the amount of change between the times was analysed, only the change in TT between the 21st day and the 6th week was found to be statistically significant (p=0.028).
Conclusion: In our study, it can be said that the use of ABS following FGG surgery has a positive effect on intraoperative bleeding, short-term epithelialization and long-term TT but it cannot provide an effective superiority compared to collagen sponge alone in terms of early wound healing, postoperative pain, and analgesic usage.

Keywords

Ankaferd hemostatic, free gingival graft, wound healing

Supporting Institution

YOK

Project Number

YOK

Thanks

Authors of this study thank to Prof. Dr. Sıddık Keskin (Department of Biostatistics, Faculty of Medicine, Van Yuzuncu Yil University)

Ankaferd Kanama Durdurucunun Donör Bölgede Yara İyileşmesi Üzerine Etkisinin İncelenmesi

Abstract

Amaç: Bu çalışmanın amacı, serbest dişeti grefti (SDG) cerrahisi sonrası palatinal donör alanda Ankaferd Blood Stopper (ABS) kullanımının etkisini değerlendirmektir.
Gereç ve Yöntemler: Toplam 12 hasta (24 palatal bölge) çalışmaya dahil edildi. Her hastada donör bölgeler rasgele iki gruba ayrıldı. Test grubuna ABS+kollajen ped uygulandı. Kontrol grubuna ise sadece kollajen ped uygulandı. Kanama, epitelizasyon, duyarlılık, ağrı skoru, alınan analjezik sayısı, yara boyutu, yara iyileşme (LTH) indeksi ve doku kalınlığı (DK) açısından donör sahalar değerlendirildi.
Bulgular: İntraoperatif kanama bakımından kontrol grubunda anlamlı şekilde daha fazla hastada (n=9) kanama gözlenirken; test grubunda hiçbir hastada gözlenmedi (p=0.000). Test grubunda 14. günde daha yüksek epitelizasyon varlığı (33.3%) tespit edilmesine ragmen, epitelizasyon bakımından gruplar arasında anlamlı bir farklılık tespit edilmedi. Gruplar arasında ağrı skorları, analjezik kullanımı, yara boyutu, LTH indeksi ve DK bakımından anlamlı bir farklılık tespit edilmedi. Zamanlar arasındaki değişim miktarı incelendiğinde sadece 21. gün ile 6. hafta arasındaki TT’deki değişim, istatistiksel olarak anlamlı bulundu (p=0,028).
Sonuç: Çalışmamızda SDG cerrahisi sonrasında ABS kullanımının intraoperatif kanama, kısa dönem epitelizasyon ve uzun dönem DK’da olumlu etkisinin olduğu ancak erken dönem yara iyileşmesi, postoperatif ağrı ve analjezik tüketimi konusunda tek başına kollajen süngere kıyasla etkin bir üstünlük sağlayamadığı söylenebilir.

Keywords

Ankaferd kanama durdurucu, serbest dişeti grefti, yara iyileşmesi

Project Number

YOK

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