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Reconstruction of Defective Alveolar Bone With Non-Resorbable and Titanium Reinforced Membrane Implantation Success

Year 2025, Volume: 7 Issue: 2, 203 - 212, 29.08.2025

Abstract

Aim: The aim of this study is to present the clinical success of cases in which implants were placed in defective alveolar bone in a single surgical procedure.
Material and Methods: Thirty-three patients with alveolar bone defects in the maxillary canine and premolar regions were included in the study. Before the procedure, cone-beam computed tomography (CBCT) images were obtained from all patients and the heights of the defective walls were recorded. In the surgical operation, primary stability of the implant was ensured, guided bone regeneration was applied. The prosthetic restoration was completed as cemented or screwed. Six months after this stage, the amount of bone regained was recorded by CBCT imaging. Clinically, peri-implant probing depth and bleeding on probing indexes were examined. The Mann-Whitney U test was applied for comparisons between types of restoration, while bone heights were compared using the Wilcoxon Sign test (p<0.05).
Results: The mean total bone height gain was 8.91 ± 1.30 mm. The pocket depth was significantly greater in cemented restorations compared to screwed restorations (p=0.006). The mean pink esthetic score score was 12.3 ± 1.8 and the mean white esthetic score score was 8.4 ± 1.5.
Conclusion: In cases where there is a defect of more than half the implant length on one or both sides of the alveolar bone, implants can be placed in a single session with a meticulous surgical approach and appropriate material. The use of screw retainers in prosthetic restorations has been found to be more successful than cemented restorations.

Ethical Statement

ethical committee was approved

Supporting Institution

NONE

Thanks

I would like to thank Assoc. Prof. Dr. Tuğçe Temur for allowing and supporting us to use the CBCT imaging device many times in accordance with the study.

References

  • Karadayı Yüzükcü AE, Yerliyurt K. How important are the implant inclination and the infrastructure material used in implant supported fixed prosthesis? Cumhuriyet Dent J. 2021;24:395-402.
  • Chiapasco M, Casentini P, Tommasato G, Dellavia C, Del Fabbro M. Customized CAD/CAM titanium meshes for the guided bone regeneration of severe alveolar ridge defects: Preliminary results of a retrospective clinical study in humans. Clin Oral Implants Res. 2021;32:498-510.
  • Lee SH, Moon JH, Jeong CM, Bae EB, et al. The mechanical properties and biometrical effect of 3D preformed titanium membrane for guided bone regeneration on alveolar bone defect. BioMed Res Int. 2017;1:7102123.
  • Dumanlı D, Şeker Ç, Geduk G. Retrospective radiographic evaluation of implant complications: CBCT-based study. NEU Dent J. 2024;6(special issue):9-17.
  • Fugui Z, Yucheng S, Lixin Q, Hongchang L, et al. Expert consensus on the bone augmentation surgery for alveolar bone defects. J Prev Ther Stomatol. 2022;12:229-36.
  • Gan LM, Zhou QR, Zhang Y, Yu YC, et al. Alveolar bone morphologic predictors for guided bone regeneration outcome in anterior maxilla. Int Dent J. 2024;741:102-9.
  • Chappuis V, Shahim K, Buser R, Koller E, et al. Novel collagen matrix to increase tissue thickness simultaneous with guided bone regeneration and implant placement in esthetic implant sites: A feasibility study. Int J Periodontics Restorative. 2018;38:575-82.
  • Tonetti MS, Jung RE, Avila‐Ortiz G, Blanco J, et al. Management of the extraction socket and timing of implant placement: Consensus report and clinical recommendations of group 3 of the XV European Workshop in Periodontology. J Clin Periodontology. 2019;46:183-94.
  • Dahlin C, Linde A, Gottlow J, Nyman S. Healing of bone defects by guided tissue regeneration. Plast Reconstr Surg. 1988;81:672-6.
  • Qian SJ, Pu YP, Zhang XM, Wu XY, et al. Clinical, radiographic, and esthetic evaluation of immediate implant placement with buccal bone dehiscence in the anterior maxilla: A 1‐year prospective case series. Clin Implant Dent Related Res. 2023;25:3-10.
  • Ayranci F, Gungormus M, Omezli MM, Gundogdu B. The effect of alendronate on various graft materials used in maxillary sinus augmentation: a rabbit study. Iran Red Crescent. Med Journal. 2015;17: e33569.
  • Narasimhan S, Tiwari S, Datri R, Basu P, et al. WiFi Mesh for guided bone regeneration: A novel approach. J Maxillofac Oral Surg. 2021;20:362-8.
  • Cucchi A, Vignudelli E, Napolitano A, Marchetti C, Corinaldesi G. Evaluation of complication rates and vertical bone gain after guided bone regeneration with non-resorbable membranes versus titanium meshes and resorbable membranes. A randomized clinical trial. Clin Implant Dent Relat Res. 2017;19:821-32.
  • Urban IA, Montero E, Monje A, Sanz-Sánchez I. Effectiveness of vertical ridge augmentation interventions: A systematic review and meta-analysis. J Clin Periodontol. 2019;46:319-39.
  • Thoma DS, Bienz SP, Figuero E, Jung RE, Sanz‐Martín I. Efficacy of lateral bone augmentation performed simultaneously with dental implant placement: A systematic review and meta‐analysis. J Clin Periodontol. 2019;46:257-76.
  • Sáez-Alcaide LM, Gallego BG, Moreno JF, Navarro MM, et al. Complications associated with vertical bone augmentation techniques in implant dentistry: A systematic review of clinical studies published in the last ten years. J Stomatol Oral Maxillofac Surg. 2023;124:101574.
  • Meloni SM, Jovanovic SA, Urban I, Canullo L, et al. Horizontal ridge augmentation using GBR with a native collagen membrane and 1:1 Ratio of particulated xenograft and autologous bone: A 1‐year prospective clinical study. Clin Implant Dent Relat Res. 2017;19:38-45.
  • Galindo‐Moreno P, León‐Cano A, Ortega‐Oller I, Monje A, et al. Marginal bone loss as success criterion in implant dentistry: beyond 2 mm. Clin Oral Implants Res. 2015;26:e28-34.
  • Windael S, Collaert B, De Buyser S, Vervaeke S, De Bruyn H. A 10‐Year Retrospective Clinical Study to Identify Risk Indicators for Peri‐Implant Bone Loss and Implant Failure. Clin Oral Implants Res. 2025;36:202-19.
  • Belser UC, Grütter L, Vailati F, Bornstein MM, et al. Outcome evaluation of early placed maxillary anterior single-tooth implants using objective esthetic criteria: a cross-sectional, retrospective study in 45 patients with a 2-to 4-year follow-up using pink and white esthetic scores. J Periodontol. 2009;80:140-51.
  • Cosyn J, Eghbali A, De Bruyn H, Collys K, et al. Immediate single‐tooth implants in the anterior maxilla: 3‐year results of a case series on hard and soft tissue response and aesthetics. J Clin Periodontology. 2011;38:746-53.
  • Braun D, Chappuis V, Fonseca M, Raabe C, et al. Reproducibility and Reliability of Intraoral Scanners for Evaluating Peri‐Implant Tissues and Implant‐Supported Prostheses: A Cross‐Sectional Study. J Esthet Restor Dent. 2025;37:1273-83.
  • Sailer I, Mühlemann S, Zwahlen M, Hämmerle CH, Schneider D. Cemented and screw-retained implant reconstructions: a systematic review of the survival and complication rates. Clin Oral Implants Res. 2012;23:163-201.
  • Fiorillo L, D’Amico C, Ronsivalle V, Cicciù M, Cervino G. Single Dental Implant Restoration: Cemented or Screw-Retained? A Systematic Review of Multi-Factor Randomized Clinical Trials. Prosthesis. 2024;6:871-886.
  • Ronda M, Rebaudi A, Torelli L, Stacchi C. Expanded vs. dense polytetrafluoroethylene membranes in vertical ridge augmentation around dental implants: a prospective randomized controlled clinical trial. Clin Oral Implants res. 2014;25:859-66.
  • Alshawy E. The prevalence and categories of impacted maxillary canines: A radiographic study. Cureus. 2023;15: e40070.
  • Urban IA, Lozada JL, Jovanovic SA, Nagursky H, Nagy K. Vertical ridge augmentation with titanium-reinforced, dense-PTFE membranes and a combination of particulated autogenous bone and anorganic bovine bone–derived mineral: a prospective case series in 19 patients. Int J Oral Maxillofac Implant. 2014;29:185-93.
  • Inchingolo F, Inchingolo AM, Ferrante L, Inchingolo AD, et al. Techniques and materials in implant rehabilitation surgery using sinus lift and GBR. Dent Cadmos. 2024;92:226-36.
  • Fürhauser R, Florescu D, Benesch T, Haas R, et al. Evaluation of soft tissue around single‐tooth implant crowns: the pink esthetic score. Clin Oral Implants Res. 2005;16:639-44.
  • Troeltzsch M, Troeltzsch M, Kauffmann P, Gruber R, et al. Clinical efficacy of grafting materials in alveolar ridge augmentation: A systematic review. J Cranio-Maxillofac Surg. 2016;44:1618-29.
  • Khojasteh A, Kheiri L, Motamedian SR, Nadjmi N. Regenerative medicine in the treatment of alveolar cleft defect: A systematic review of the literature. J Cranio-Maxillofac Surg. 2017;45:608-13.
  • Elgali I, Omar O, Dahlin C, Thomsen P. Guided bone regeneration: materials and biological mechanisms revisited. Eur J Oral Sci. 2017;125:315-37.
  • Karaaslan F, Terzi M. Association between peri-implant diseases and cement-retained prosthesis: A review. Ata Diş Hek Fak Derg. 2016;80-4.

Defektif Alveolar Kemiğin Rezorbe Olmayan ve Titanyumla Güçlendirilmiş Membranla Rekonstrüksiyonu ve İmplantasyon Başarısı

Year 2025, Volume: 7 Issue: 2, 203 - 212, 29.08.2025

Abstract

Amaç: Bu çalışmanın amacı, implantların defektif alveoler kemiğe tek bir cerrahi prosedürle yerleştirildiği vakaların klinik başarısını sunmaktır.
Gereç ve Yöntemler: Maksiller kanin ve premolar bölgelerinde alveolar kemik defekti olan 33 hasta çalışmaya dahil edildi. İşlem öncesinde tüm hastalardan konik ışınlı bilgisayarlı tomografi (CBCT) görüntüleri elde edildi ve defektif duvarların yükseklikleri kaydedildi. Cerrahi operasyonda implantın primer stabilitesi sağlandı, yönlendirilmiş kemik rejenerasyonu uygulandı. Protetik restorasyon simante veya vidalı olarak tamamlandı. Bu aşamadan altı ay sonra, kazanılan kemik miktarı CBCT görüntüleme ile kaydedildi. Klinik olarak, peri-implant sondalama derinliği ve sondalamada kanama indeksleri incelendi. Restorasyon tipleri arasındaki karşılaştırmalar için Mann-Whitney U testi uygulanırken, kemik yükseklikleri Wilcoxon İşaret testi kullanılarak karşılaştırıldı (p<0.05).
Bulgular: Ortalama toplam kemik yüksekliği kazancı 8.91 ± 1.30 mm idi. Cep derinliği simante restorasyonlarda vidalı restorasyonlara göre anlamlı olarak daha fazlaydı (p=0.006). Ortalama pembe estetik skor 12.3 ± 1.8 ve ortalama beyaz estetik skor 8.4 ± 1.5 idi.
Sonuçlar: Alveoler kemiğin bir veya iki tarafında implant uzunluğunun yarısından fazla defekt olduğu durumlarda, titiz bir cerrahi yaklaşım ve uygun materyal ile implantlar tek seansta yerleştirilebilir. Protetik restorasyonlarda vida tutucuların kullanımı simante restorasyonlara göre daha başarılı bulunmuştur.

Ethical Statement

SUNULDU

Supporting Institution

YOK

Thanks

I would like to thank Assoc. Prof. Dr. Tuğçe Temur for allowing and supporting us to use the CBCT imaging device many times in accordance with the study.

References

  • Karadayı Yüzükcü AE, Yerliyurt K. How important are the implant inclination and the infrastructure material used in implant supported fixed prosthesis? Cumhuriyet Dent J. 2021;24:395-402.
  • Chiapasco M, Casentini P, Tommasato G, Dellavia C, Del Fabbro M. Customized CAD/CAM titanium meshes for the guided bone regeneration of severe alveolar ridge defects: Preliminary results of a retrospective clinical study in humans. Clin Oral Implants Res. 2021;32:498-510.
  • Lee SH, Moon JH, Jeong CM, Bae EB, et al. The mechanical properties and biometrical effect of 3D preformed titanium membrane for guided bone regeneration on alveolar bone defect. BioMed Res Int. 2017;1:7102123.
  • Dumanlı D, Şeker Ç, Geduk G. Retrospective radiographic evaluation of implant complications: CBCT-based study. NEU Dent J. 2024;6(special issue):9-17.
  • Fugui Z, Yucheng S, Lixin Q, Hongchang L, et al. Expert consensus on the bone augmentation surgery for alveolar bone defects. J Prev Ther Stomatol. 2022;12:229-36.
  • Gan LM, Zhou QR, Zhang Y, Yu YC, et al. Alveolar bone morphologic predictors for guided bone regeneration outcome in anterior maxilla. Int Dent J. 2024;741:102-9.
  • Chappuis V, Shahim K, Buser R, Koller E, et al. Novel collagen matrix to increase tissue thickness simultaneous with guided bone regeneration and implant placement in esthetic implant sites: A feasibility study. Int J Periodontics Restorative. 2018;38:575-82.
  • Tonetti MS, Jung RE, Avila‐Ortiz G, Blanco J, et al. Management of the extraction socket and timing of implant placement: Consensus report and clinical recommendations of group 3 of the XV European Workshop in Periodontology. J Clin Periodontology. 2019;46:183-94.
  • Dahlin C, Linde A, Gottlow J, Nyman S. Healing of bone defects by guided tissue regeneration. Plast Reconstr Surg. 1988;81:672-6.
  • Qian SJ, Pu YP, Zhang XM, Wu XY, et al. Clinical, radiographic, and esthetic evaluation of immediate implant placement with buccal bone dehiscence in the anterior maxilla: A 1‐year prospective case series. Clin Implant Dent Related Res. 2023;25:3-10.
  • Ayranci F, Gungormus M, Omezli MM, Gundogdu B. The effect of alendronate on various graft materials used in maxillary sinus augmentation: a rabbit study. Iran Red Crescent. Med Journal. 2015;17: e33569.
  • Narasimhan S, Tiwari S, Datri R, Basu P, et al. WiFi Mesh for guided bone regeneration: A novel approach. J Maxillofac Oral Surg. 2021;20:362-8.
  • Cucchi A, Vignudelli E, Napolitano A, Marchetti C, Corinaldesi G. Evaluation of complication rates and vertical bone gain after guided bone regeneration with non-resorbable membranes versus titanium meshes and resorbable membranes. A randomized clinical trial. Clin Implant Dent Relat Res. 2017;19:821-32.
  • Urban IA, Montero E, Monje A, Sanz-Sánchez I. Effectiveness of vertical ridge augmentation interventions: A systematic review and meta-analysis. J Clin Periodontol. 2019;46:319-39.
  • Thoma DS, Bienz SP, Figuero E, Jung RE, Sanz‐Martín I. Efficacy of lateral bone augmentation performed simultaneously with dental implant placement: A systematic review and meta‐analysis. J Clin Periodontol. 2019;46:257-76.
  • Sáez-Alcaide LM, Gallego BG, Moreno JF, Navarro MM, et al. Complications associated with vertical bone augmentation techniques in implant dentistry: A systematic review of clinical studies published in the last ten years. J Stomatol Oral Maxillofac Surg. 2023;124:101574.
  • Meloni SM, Jovanovic SA, Urban I, Canullo L, et al. Horizontal ridge augmentation using GBR with a native collagen membrane and 1:1 Ratio of particulated xenograft and autologous bone: A 1‐year prospective clinical study. Clin Implant Dent Relat Res. 2017;19:38-45.
  • Galindo‐Moreno P, León‐Cano A, Ortega‐Oller I, Monje A, et al. Marginal bone loss as success criterion in implant dentistry: beyond 2 mm. Clin Oral Implants Res. 2015;26:e28-34.
  • Windael S, Collaert B, De Buyser S, Vervaeke S, De Bruyn H. A 10‐Year Retrospective Clinical Study to Identify Risk Indicators for Peri‐Implant Bone Loss and Implant Failure. Clin Oral Implants Res. 2025;36:202-19.
  • Belser UC, Grütter L, Vailati F, Bornstein MM, et al. Outcome evaluation of early placed maxillary anterior single-tooth implants using objective esthetic criteria: a cross-sectional, retrospective study in 45 patients with a 2-to 4-year follow-up using pink and white esthetic scores. J Periodontol. 2009;80:140-51.
  • Cosyn J, Eghbali A, De Bruyn H, Collys K, et al. Immediate single‐tooth implants in the anterior maxilla: 3‐year results of a case series on hard and soft tissue response and aesthetics. J Clin Periodontology. 2011;38:746-53.
  • Braun D, Chappuis V, Fonseca M, Raabe C, et al. Reproducibility and Reliability of Intraoral Scanners for Evaluating Peri‐Implant Tissues and Implant‐Supported Prostheses: A Cross‐Sectional Study. J Esthet Restor Dent. 2025;37:1273-83.
  • Sailer I, Mühlemann S, Zwahlen M, Hämmerle CH, Schneider D. Cemented and screw-retained implant reconstructions: a systematic review of the survival and complication rates. Clin Oral Implants Res. 2012;23:163-201.
  • Fiorillo L, D’Amico C, Ronsivalle V, Cicciù M, Cervino G. Single Dental Implant Restoration: Cemented or Screw-Retained? A Systematic Review of Multi-Factor Randomized Clinical Trials. Prosthesis. 2024;6:871-886.
  • Ronda M, Rebaudi A, Torelli L, Stacchi C. Expanded vs. dense polytetrafluoroethylene membranes in vertical ridge augmentation around dental implants: a prospective randomized controlled clinical trial. Clin Oral Implants res. 2014;25:859-66.
  • Alshawy E. The prevalence and categories of impacted maxillary canines: A radiographic study. Cureus. 2023;15: e40070.
  • Urban IA, Lozada JL, Jovanovic SA, Nagursky H, Nagy K. Vertical ridge augmentation with titanium-reinforced, dense-PTFE membranes and a combination of particulated autogenous bone and anorganic bovine bone–derived mineral: a prospective case series in 19 patients. Int J Oral Maxillofac Implant. 2014;29:185-93.
  • Inchingolo F, Inchingolo AM, Ferrante L, Inchingolo AD, et al. Techniques and materials in implant rehabilitation surgery using sinus lift and GBR. Dent Cadmos. 2024;92:226-36.
  • Fürhauser R, Florescu D, Benesch T, Haas R, et al. Evaluation of soft tissue around single‐tooth implant crowns: the pink esthetic score. Clin Oral Implants Res. 2005;16:639-44.
  • Troeltzsch M, Troeltzsch M, Kauffmann P, Gruber R, et al. Clinical efficacy of grafting materials in alveolar ridge augmentation: A systematic review. J Cranio-Maxillofac Surg. 2016;44:1618-29.
  • Khojasteh A, Kheiri L, Motamedian SR, Nadjmi N. Regenerative medicine in the treatment of alveolar cleft defect: A systematic review of the literature. J Cranio-Maxillofac Surg. 2017;45:608-13.
  • Elgali I, Omar O, Dahlin C, Thomsen P. Guided bone regeneration: materials and biological mechanisms revisited. Eur J Oral Sci. 2017;125:315-37.
  • Karaaslan F, Terzi M. Association between peri-implant diseases and cement-retained prosthesis: A review. Ata Diş Hek Fak Derg. 2016;80-4.
There are 33 citations in total.

Details

Primary Language English
Subjects Oral and Maxillofacial Surgery
Journal Section RESEARCH ARTICLE
Authors

Nida Geçkil 0000-0003-3252-8398

Publication Date August 29, 2025
Submission Date November 18, 2024
Acceptance Date April 9, 2025
Published in Issue Year 2025 Volume: 7 Issue: 2

Cite

Vancouver Geçkil N. Reconstruction of Defective Alveolar Bone With Non-Resorbable and Titanium Reinforced Membrane Implantation Success. NEU Dent J. 2025;7(2):203-12.