Case Report
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İki Taraflı Senkronize Renal Hücreli Karsinom ve Tek Aşamalı Nefrektomi: Olgu Sunumu

Year 2025, Volume: 20 Issue: 3, 208 - 211, 20.10.2025
https://doi.org/10.33719/nju1664889

Abstract

References

  • 1. Suzuki T, Takahashi H, Yao K, Inagi K, Nakayama M, Makoshi T, et al. Multiple primary malignancies in the head and neck: a clinical review of 121 patients. Acta Otolaryngol Suppl. 2002;(547):88-92. https://doi.org/10.1080/000164802760057662
  • 2. Wiklund F, Tretli S, Choueiri TK, Signoretti S, Fall K, Adami HO. Risk of bilateral renal cell cancer. J Clin Oncol. 2009;27(23):3737-41. https://doi.org/10.1200/ JCO.2008.20.6524
  • 3. Kim JK, Lee H, Oh JJ, Lee S, Hong SK, Lee SE, et al. Synchronous Bilateral RCC Is Associated With Poor Recurrence-Free Survival Compared With Unilateral RCC: A Single-Center Study With Propensity Score Matching Analysis. Clin Genitourin Cancer. 2019;17(3):e570-e580. https://doi.org/10.1016/j. clgc.2019.02.008
  • 4. Kotb A, Alaref A, Kisselgoff D, Ismail A, Rozenberg R, Burute N, et al. Bilateral Single-Stage Nephrectomy for Synchronous Bilateral Renal Cell Carcinoma. J Kidney Cancer VHL. 2021;8(1):7-11. https://doi.org/10.15586/jkcvhl.v8i1.151
  • 5. Klatte T, Wunderlich H, Patard JJ, Kleid MD, Lam JS, Junker K, et al. Clinicopathological features and prognosis of synchronous bilateral renal cell carcinoma: an international multicentre experience. BJU Int. 2007;100(1):21-5. https://doi.org/10.1111/j.1464- 410X.2007.06877.x
  • 6. Mason RJ, Atwell T, Lohse C, Bhindi B, Schmit G, Schmitz J, et al. Synchronous nephron-sparing approaches for bilateral renal masses: peri-operative and renal functional outcomes. BJU Int. 2018;122(2):243- 248. https://doi.org/10.1111/bju.14221
  • 7. Kotb A, Ismail A, Elmansy H, Prowse O, Shahrour W. Spontaneous Retroperitoneal Hemorrhage in a Patient with Acquired Cystic Kidney Disease. J Kidney Cancer VHL. 2020;7(1):1-4. https://doi.org/10.15586/ jkcvhl.2020.123
  • 8. Wang B, Gong H, Zhang X, Li H, Ma X, Song E, et al. Bilateral Synchronous Sporadic Renal Cell Carcinoma: Retroperitoneoscopic Strategies and Intermediate Outcomes of 60 Patients. PLoS One. 2016;11(5):e0154578. https://doi.org/10.1371/journal.pone.0154578
  • 9. Packiam TV, Tsivian M, Lohse CM, Cheville JC, Boorjian SA, Thompson RH, et al. Simultaneous versus staged partial nephrectomies for bilateral synchronous solid renal masses. Urol Oncol. 2020;38(7):640.e13-640. e22. https://doi.org/10.1016/j.urolonc.2020.04.002

Bilateral Synchronous Renal Cell Carcinoma and Single-Stage Nephrectomy: A Case Report

Year 2025, Volume: 20 Issue: 3, 208 - 211, 20.10.2025
https://doi.org/10.33719/nju1664889

Abstract

Bilateral renal cell carcinoma (RCC) is a rare condition, accounting for approximately 0.3% of all kidney cancer cases. There is no consensus on the surgical approach for treating bilateral synchronous renal masses. In this article, we present a single-stage surgical approach for a 76-year-old male patient with large bilateral synchronous RCC. Surgical intervention involved performing a right-sided partial nephrectomy concurrently with a total nephrectomy on the left kidney. No metastasis or local recurrence was observed in the postoperative 30-month follow-up. In selected cases, single-stage bilateral nephrectomy/partial nephrectomy can be safely performed in experienced centers.

Supporting Institution

No funding

Thanks

The authors would like to thank Dr. Muhammet Emin Güldür for his cooperation especially on pathological assessments.

References

  • 1. Suzuki T, Takahashi H, Yao K, Inagi K, Nakayama M, Makoshi T, et al. Multiple primary malignancies in the head and neck: a clinical review of 121 patients. Acta Otolaryngol Suppl. 2002;(547):88-92. https://doi.org/10.1080/000164802760057662
  • 2. Wiklund F, Tretli S, Choueiri TK, Signoretti S, Fall K, Adami HO. Risk of bilateral renal cell cancer. J Clin Oncol. 2009;27(23):3737-41. https://doi.org/10.1200/ JCO.2008.20.6524
  • 3. Kim JK, Lee H, Oh JJ, Lee S, Hong SK, Lee SE, et al. Synchronous Bilateral RCC Is Associated With Poor Recurrence-Free Survival Compared With Unilateral RCC: A Single-Center Study With Propensity Score Matching Analysis. Clin Genitourin Cancer. 2019;17(3):e570-e580. https://doi.org/10.1016/j. clgc.2019.02.008
  • 4. Kotb A, Alaref A, Kisselgoff D, Ismail A, Rozenberg R, Burute N, et al. Bilateral Single-Stage Nephrectomy for Synchronous Bilateral Renal Cell Carcinoma. J Kidney Cancer VHL. 2021;8(1):7-11. https://doi.org/10.15586/jkcvhl.v8i1.151
  • 5. Klatte T, Wunderlich H, Patard JJ, Kleid MD, Lam JS, Junker K, et al. Clinicopathological features and prognosis of synchronous bilateral renal cell carcinoma: an international multicentre experience. BJU Int. 2007;100(1):21-5. https://doi.org/10.1111/j.1464- 410X.2007.06877.x
  • 6. Mason RJ, Atwell T, Lohse C, Bhindi B, Schmit G, Schmitz J, et al. Synchronous nephron-sparing approaches for bilateral renal masses: peri-operative and renal functional outcomes. BJU Int. 2018;122(2):243- 248. https://doi.org/10.1111/bju.14221
  • 7. Kotb A, Ismail A, Elmansy H, Prowse O, Shahrour W. Spontaneous Retroperitoneal Hemorrhage in a Patient with Acquired Cystic Kidney Disease. J Kidney Cancer VHL. 2020;7(1):1-4. https://doi.org/10.15586/ jkcvhl.2020.123
  • 8. Wang B, Gong H, Zhang X, Li H, Ma X, Song E, et al. Bilateral Synchronous Sporadic Renal Cell Carcinoma: Retroperitoneoscopic Strategies and Intermediate Outcomes of 60 Patients. PLoS One. 2016;11(5):e0154578. https://doi.org/10.1371/journal.pone.0154578
  • 9. Packiam TV, Tsivian M, Lohse CM, Cheville JC, Boorjian SA, Thompson RH, et al. Simultaneous versus staged partial nephrectomies for bilateral synchronous solid renal masses. Urol Oncol. 2020;38(7):640.e13-640. e22. https://doi.org/10.1016/j.urolonc.2020.04.002
There are 9 citations in total.

Details

Primary Language English
Subjects Urology
Journal Section Case Reports
Authors

İbrahim Halil Albayrak 0000-0002-6448-2243

Mehmet Demir 0000-0002-3618-0547

Eyyup Sabri Pelit 0000-0001-8550-5072

İsmail Yağmur 0000-0002-4208-5095

Publication Date October 20, 2025
Submission Date April 5, 2025
Acceptance Date June 3, 2025
Published in Issue Year 2025 Volume: 20 Issue: 3

Cite

Vancouver Albayrak İH, Demir M, Pelit ES, Yağmur İ. Bilateral Synchronous Renal Cell Carcinoma and Single-Stage Nephrectomy: A Case Report. New J Urol. 2025;20(3):208-11.