SYNTHESIS OF ORTHO-HYDRAZONE-FUNCTIONALIZED OLIGOPHENOL VIA ENZYMATIC OXIDATIVE POLYMERIZATION

Year 2017, Volume: 6 Issue: 2, 773 - 784, 31.07.2017

Ersen Turaç

https://doi.org/10.28948/ngumuh.342077

Abstract

   Hydrazone substituted
oligophenol was synthesized via enzymatic oxidative polymerization of (E)-2-(1-(2-phenylhydrazono)ethyl)phenol
[PHEP]. Enzymatic polymerization catalyzed by Horseradish peroxidase (HRP)
enzyme and hydrogen peroxide (H₂O₂) oxidizer yielded oligophenol with
hydrazone functionality on the side-chain. Effects of various factors including solvent system,
reaction pH and temperature on the polymerization were studied. Synthesized
oligomer was characterized by nuclear magnetic resonance (¹H and ¹³C
NMR), fourier transform infrared (FT-IR), gel permeation chromatography (GPC),
ultraviolet-visible (UV-Vis), cyclic voltammetry (CV) and thermogravimetric
analysis (TGA/DTG).

Keywords

Enzymatic oxidative polymerization, Horseradish peroxidase, hydrazone

ENZİMATİK OKSİDATİF POLİMERİZASYON İLE ORTO-HİDRAZON-FONKSİYONLU OLİGOFENOL SENTEZİ

Abstract

   Hidrazon fonksiyonlu oligofenol, (E)-2-(1-(2-fenilhidrazon)etil)fenol
[FHEF] enzimatik oksidatif polimerizasyon yöntemiyle sentezlenmiştir. Yan
zincirinde hidrazon fonksiyonel grubu içeren fenol türevinin enzimatik oksidatif polimerizasyonunda;
katalizör olarak Horseradish peroksidaz
(HRP) enzimi, yükseltgeyici olarak ise Hidrojen peroksit (H₂O₂) kullanılmıştır. Polimerleşme üzerine reaksiyon sıcaklığı, reaksiyon pH’sı
ve çözücü sistemleri gibi değişik parametrelerin etkileri çalışılmıştır.
Sentezlenen oligomerin karakterizasyonu nükleer magnetic rezonans (¹H
ve ¹³C NMR), infrared spektroskopisi (FT-IR), jel geçirgenlik
kromotoğrafisi (GPC), ultraviyole spektroskopisi (UV-Vis), dönüşümlü voltametri
(CV) ve termogravimetrik analiz (TGA/DTA) teknikleri ile yapılmıştır.

Keywords

Enzimatik oksidatif polimerleşme, horseradish peroksidaz, hidrazon, hidrojen peroksit

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