Purpose: Here, hyperoside (HYP) was investigated against ovarian tissue injury induced by bilateral ovarian torsion detorsion (T/D) model. Material and Methods: 18 Sprague Dawley female rats were grouped as sham, torsion detorsion (T/D) and T/D+HYP. Sham group, abdominal incision was performed and repaired with no additional intervention. T/D group, T/D model was established. T/D+HYP group, HYP was administered by oral gavage prior to detorsion. Following detorsion, rats were sacrificed and the ovarian tissues were excised. Results and Conclusion: Oxidant parameters declined and antioxidant values elevated in T/D group compared to sham group. HYP treatment decreased oxidant biomarkers and increased antioxidant mediators. After all, HYP prevented ovarian tissue injury generated by T/D model in rats.
Primary Language | English |
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Subjects | Medical Physiology |
Journal Section | Research Articles |
Authors | |
Publication Date | June 15, 2020 |
Submission Date | May 21, 2020 |
Published in Issue | Year 2020 Volume: 1 Issue: 1 |
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