Role of Hyperoside on Ovarian Tissue Damage Created by Ovarian Torsion Detorsion

Year 2020, Volume: 1 Issue: 1, 1 - 5, 15.06.2020

Mustafa Can Güler Ayhan Tanyeli

Abstract

Purpose: Here, hyperoside (HYP) was investigated against ovarian tissue injury induced by bilateral ovarian torsion detorsion (T/D) model. Material and Methods: 18 Sprague Dawley female rats were grouped as sham, torsion detorsion (T/D) and T/D+HYP. Sham group, abdominal incision was performed and repaired with no additional intervention. T/D group, T/D model was established. T/D+HYP group, HYP was administered by oral gavage prior to detorsion. Following detorsion, rats were sacrificed and the ovarian tissues were excised. Results and Conclusion: Oxidant parameters declined and antioxidant values elevated in T/D group compared to sham group. HYP treatment decreased oxidant biomarkers and increased antioxidant mediators. After all, HYP prevented ovarian tissue injury generated by T/D model in rats.

Keywords

Hyperoside, Ovarian Torsion Detorsion, Ovary, Rat

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