PREMATÜRE OVARİAN YETMEZLİKLER

Öz

Prematüre ovarian yetmezlik, basitçe overlerin sahip olduğu foliküler kapasite veya fonksiyonu normal menopozal süreç gelişmeden çok daha önce kaybetmesi olarak düşünülebilir. Etyolojisinde genetik nedenler, overleri etkileyen toksik ajanlar veya cerrahi prosedürler, otoimmun nedenler, enfeksiyonlar, kalısal problemler bulunabildiği gibi; bazen multifaktöriel olup birçok durum bir arada görüebilir. Kimi zaman ise nedenini tam olarak belirlemek mümkün olmamaktadır. Prematüre ovarian yetmezlikli kişilerin erken tespit edilmesi ve uygun tedaviye yönlendirilmeleri hem fertiliteleri açısından, hem genetik durumlarda uygun vücut ve cinsiyet gelişimini sağlayabilmeleri açısından, hem de sonraki dönemlerdeki hayat kalitelerinin artırılması açısından çok büyük önem arzetmektedir.

Anahtar Kelimeler

• Menopoz,Over Rezervi,Ovarian Yetmezlik,Foliküler Atrezi,İnfertilite

PREMATURE OVARIAN FAILURE

Abstract

     Premature ovarian failure may simply be thought as losing the follicular capacity or function of ovaries before the development of normal menopausal period. As well as genetic causes, toxic agents or surgical procedures affecting the ovaries, autoimmune reasons, enfections, hereditary problems can be found in ovarian failure ethiology; sometimes it can be multifactorial and several stuations can be seen together. Sometimes it is not possible to determine it’s cause. To determine the people with remature ovarian failure and refering them to appropriate treatment is very important because of both their fertilities, providing appropriate body and gender developments for genetic causes and in terms of increasing the quality of life in next periods.  

Keywords

• Menopause,Ovarian Reserve,Ovarian Failure,Follicular Atresia,İnfertility

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