SIÇANLARDA İN VİVO OLARAK ELEKTROMANYETİK ALANA MARUZ KALMANIN BEYİN DOKULARINDAKİ KATEKOLAMİNERJİK NÖROTRANSMİTTER DÜZEYLERİNE ETKİSİ

Year 2016, Volume: 11 Issue: 3, 1 - 8, 06.06.2016

Kemal Balıkçı , İhsan Serhatlıoğlu Selim Kutlu Mustafa Poyraz

Abstract

Bu çalışmada, mobil telefonların oluşturduğu elektromanyetik alan (EMA)’a maruz bırakılan yetişkin erkek sıçanların beyinlerinde, kimyasal haberci olarak görev yapan katekolaminerjik nörotransmitterler noradrenalin (NA) ve dopamin (DA) konsantrasyonlarının değişip değişmediği araştırılmıştır. Bu amaçla, 900 ve 1800 MHz frekanslı EMA, 1 ve 5 saat süreyle uygulandıktan sonra beynin hipokampus, hipotalamus, striatum ve frontal korteks bölgelerinde NA ve DA seviyeleri yüksek performanslı sıvı kromatografisi ve elektrokimyasal dedektör sistemiyle (HPLC-ECD) analiz edilmiştir. Kontrol grubuyla karşılaştırıldığında, deney gruplarındaki NA ve DA miktarlarının, istatistiksel olarak anlamlı şekilde yüksek olduğu belirlenmiştir. Sonuç olarak mobil telefonların, beyinde katekolamin düzeylerini değiştirebileceği ve bunun da, motor aktivite, öğrenme, bellek, duygu durum ve davranış fonksiyonları üzerinde olumsuz etkilere yol açabileceği değerlendirilmiştir.

Keywords

Elektromanyetik Alan, Mobil Telefon, Sıçan Beyni, Noradrenalin, Dopamin

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