Sacroileitis Developing in Irregularly Treated Brusellosis

Abstract

Brucellosis; Fever, also known as corrugated fever, is a zoonotic disease charactarized by chills and muscle aches. It can be seen endemic in many countries including our country. Consumption of unpasteurized dairy products is the most common mode of transmission. Diagnosis is made by culture of the organism and increase in antibody titer in serum samples. Complications affecting many systems, mostly osteoarticular, are seen in the disease. In our case, a case of sacroileitis developed as a result of irregular treatment in a patient who was engaged in animal husbandry and was diagnosed with brucellosis is presented. In our case, it was started that osteoarticular involvement could develop under treatment and the importance of regular treatment at correct doses was emphasized.

Keywords

• Brucellozis
• Complication
• Sacroiliitis

Düzensiz Tedavi Edilen Brusellozda Gelişen Sakroileit

Abstract

Bruselloz; Ondülan ateş olarak da bilinen ateş, terleme ve kas ağrıları ile seyreden zoonotik bir hastalıktır. Endemik olarak ülkemizin de içinde bulunduğu birçok ülkede görülebilmektedir. Pastörize edilmemiş süt ürünleri tüketimi en sık bulaş yoludur. Tanısı organizmanın kültür ile üretimi ve serum numunelerinde antikor titre artışı ile konulur. Hastalıkta en çok osteoartiküler olmak üzere birçok sistemi etkileyen komplikasyonlar görülür. Olgumuzda hayvancılıkla uğraşan ve brusellozis tanısı alan hastada düzensiz tedavi sonucu gelişen sakroileit vakası sunulmuştur. Olgumuzda osteoartiküler tutulumun tedavi altında da gelişebileceği ifade edilmiş ve doğru dozlarda düzenli tedavinin önemi vurgulanmak istenmiştir.

Keywords

• Bruselloz
• Komplikasyon
• Sakroileit

References

1. The new global map of human brucellosis. Pappas G, Papadimitriou P, Akritidis N, Christou L, Tsianos EV, Lancet Infect Dis. 2006;6(2):91
2. From the discovery of the Malta fever's agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a reemerging zoonosis, Godfroid J , Cloeckaert A, Liautard JP, Kohler S, Fretin D, Walravens K, et all. 2005 May-Jun;36(3):313-26
3. Brucellosis, Pappas G, Akritidis N, Bosilkovski M, Tsianos E, N Engl J Med. 2005;352(22):2325
4. Acute Febrile Illness Caused by Brucella abortus Infection in Humans in Pakistan, Saddique A, Ali S, Akhter S, Khan I, Neubauer H, Melzer F, ett all. Int J Environ Res Public Health. 2019;16(21) Epub 2019 Oct 23.
5. Doganay M, Aygen B, Human brucellosis: an overview. Int. J. Infect. Dis. 2003;7:173-182
6. Şimşek S, Göktaş P, Coşkun D. The in vitro effect of some antibiotic combinations including Ofloxacin and Ciprofloxacin against Brucella melitensis. Marmara Medical J 1998; 11 (3);152-5.
7. Osteoarticular manifestations of human brucellosis: A review. Esmaeilnejad-Ganji SM, Esmaeilnejad-Ganji SMR, World J Orthop. 2019;10(2):54. Epub 2019 Feb 18
8. Musculoskeletal brucellosis. Arkun R, Mete BD, Semin Musculoskelet Radiol. 2011;15:470–479

9. Gheita TA, Sayed S, Azkalany GS, El Fishawy HS, Aboul-Ezz MA, Shaaban MH, et all. Subclinical sacroiliitis in brucellosis. Clinical presentation and MRI findings. Z Rheumatol. 2015;74:240–245.