İntestinal İskemi ve Reperfüzyon

Year 2015, Volume: 2 Issue: 3, 166 - 171, 01.09.2015

Sait Bayram

Abstract

Keywords

-

İntestinal İskemi ve Reperfüzyon

Abstract

İskemi-reperfüzyon oldukça karmaşık bir reaksiyon olup insan organizmasında pek çok patofizyolojik sürecin
başlangıcında önemli rol alır. Biz iskemi-reperfüzyon süreçleri ile barsak iskemisi arasındaki ilişkilerin
biyokimyasal pencereden açıklanması hedeflenmiştir.

Keywords

İskemi, reperfüzyon, farmakoloji

References

• Zimmerman BJ, Granger DN. Reperfüsion injury. Surg Clin North Am 1992;72: 65-83.
• Mallick IH, Yang W, Winslet MC, Seifalian AM. Ischemia- reperfusion injury of the intestine and protective strategies against injury. Dig Dis Sci. 2004;49(9):1359-77.
• Wilhelm J. Metabolic aspects of membrane lipid peroxidation. Acta Univ Carol Med Monogr 1990;137:1-53.
• Gutteridge JMC, Halliwell B. Reoxygenation injury and antioxidant protection: Tale of two paradoxes. Arch Biochem Biophys 1990;283:223.
• Granger DN, Rutili G, McCord JM. Superoxide radicals in feline intestinal ischemia. Gastroenterology 1981;81: 22.
• Parks DA, Granger DN. Contributions of ischemia and reperfusion to mucosal lesion formation. Am J Physiol 1986;250:G749.
• Latham F. The oxygen paradox. Experiments on the effects of oxygen in human anoxia. Lancet 1951;1:77.
• Gilbert, D. L, ED. Oxygen and living process. An interdisciplinary approach. New York: Springer-Verlag; 1981.
• Hearse DJ, Humphrey RM, Chain EB. Abrupt reoxygenation of the anoxic potassium arrested rat heart: A study of myocardial enzyme release. J Mol Cell Cardiol 1973;5:395.
• Fridovich I. Hypoxia and oxygen toxicity. Adv Neurol 1979; 26: 255.
• Gutteridge JMC, Halliwell B. Reoxygenation injury and antioxidant protection: Tale of two paradoxes. Arch Biochem Biophys 1990; 283:223.
• Haglund U, Bulkley GB, Granger DN. On the pathophysiology of intestinal ischemic injury. Acta Chir Scand 1987;153:321.
• Lefer AM, Lefer DJ. Nitric oxide. II. Nitric oxide protects in intestinal inflammation. Am J Physiol 1999;276:G572.
• Zimmerman BJ, Granger DN. Reperfusion injury. Surg Clin North Am 1992;72: 65-83. 15. McGowan AJ, Ruiz-Ruiz MC, Reactive oxygen intermediate(s) (ROS): common mediatör(s) of poly(ADP- ribose) polymerase (PARP) cleavage and apoptosis. FEBS Lett 1996; 392299-303-35.
• Matalon S, Benos D, Jackson RM. Biophysical and molecular properties of amiloride-inhibitable NA+ channels in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 1996 271:L1-L22.
• Di Lisa F, Bernardi P: Mitochondrial function as a determi- nant of recovery or death in cell response to injury. Mol Cell Biochem 1998;184:37.
• Younes M, Schoenberg MH, Jung H, Fredholm BB, Haglund U, Schildberg FW: Oxidative tissue damage following regional intestinal ischemia and reperfusion in the cat. Res Exp Med(Berl) 1984;184(4):259-64.
• Harrison R: Structure and function of xanthine oxidoreductaze: Where are we now? Free Radic Biol Med 2002;33(6):774-97.
• Davies MG Juynh TTT Hagen P-O Endothelial physiology. İn İschemia-Reperfusion İnjury. Grace PA, Mathie RT (eds). Blackwell Science: London 1999;157-79.
• McCord JM. Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med. 1985;312:159-63.
• Parks, D.A. and Granger, D.N: Contributions of ischemia and reperfusion to mucosal lesion formation. Am. J. Physiol, 1986;250, G749–G753.
• Grace PA. Ischaemia-reperfusion injury. Br J Surg. 1994;81: 637-47.
• Yoshida WB. Radicais livres na síndrome da isquemia e reperfusão. Cir Vasc Angiol. 1996;12;82-95.
• Cotran RS, Kumar V, Robbins SL. Lesão e morte celular. In: Robbins: patologia estrutural e funcional. 5ed. Rio de Janeiro: Guanabara Koogan; 1996.p.1-30.
• Granger DN. Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol. 1988;255:H1269- 75.
• Montalto MC, Hart ML, Jordan JE, Wada K, Stahl GL. Role for complement in mediating intestinal nitric oxide synthase-2 and superoxide dismutase expression. Am J Physiol. 2003;285:G197-206.
• Ferreira ALA, Matsubara LS. Radicais livres: conceitos doenças relacionadas sistema de defesa e estresse oxidativo. Rev Assoc Med Brasil. 1997;43: 61-8.
• Hayward R and Lefer AM: Time course of endothelial- neutrophil interaction in splanchic artery ischemia- reperfusion. AM J Physiol 1998;275(6, Pt 2):H2080-H2086.
• Romson JL, Hook BG, Kunkel SL, et al: Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 1983;67:1016-36.
• Massberg S, Gonzalez AP, Leiderer R, Menger MD, Messmer K: İn vivo assessment of the influence of cold preservation time on microvascular reperfusion injury after experimental small bowel transplantation. Br J Surg.1998;85(1):127-33.
• Sisley AC, Desai T, Harig GM, Gewertz BL: Neutrophil depletion attenuates human intestinal reperfusion injury. J Surg Res.1994;57(1):192-6.
• Granger DN, Korthuis RJ: Physiologic mechanisms of postischemic tissue injury. Annu Rev Physiol 1995;57: 311-32
• Dallegri F, Goretti R, Ballestrero A, et al: Neutrophil-induced depletion of adenosine triphosphate in target cells: Evidence for a hypochlorous acid-mediated process. J Lab Clin Med. 1988;112:765.
• Jack RM: Function and regulation of polymorphonuclear leukocytes, in Tilney NL, Strom TB, Paul LC (eds): Transplantation Biology: Cellular and Molecular Aspects. Philadelphia, PA, Lippincott-Raven, 1996, p215Med 1988, 112:765
• Grisham DN, Lefer DJ: Modulation of leukocyte-endothelial interactions by reactive metabolites of oxygen and nitrogen: Relevance to ischemic heart disease. Free Radic Biol Med 1998;25(4-5):404-33.
• Panes J. Perry M, Granger DN: Leukocyte-endothelial cell adhesion: Avenues for therapeutic intervention. Br J Pharmacol 1999;126(3):537-50.
• Riaz AA, Wan MX, Schaefer T. Schramm R, Ekberg H, Menger MD, Jeppsson B, Thorlacius H: Fundamental and distinct roles of P-selectin and LFA-1 in ishemia /reperfusion-induced leukoocyte-endothelium interactions in the Mouse colon. Ann Surg 2002;236(6): 777-784.
• Bagge U, Amundson B, Lauritzen C: White blood cell deformability and plugging of skeletal muscle capillaries in hemorrhagic shock. Acta Physiol Scand 1980;108(2):159-63.
• Silveira M, Yoshida WB. Isquemia e reperfusão em mşsculo esquelético: mecanismo de lesão e perspectivas de tratamento. J Vasc Br. 2004;3(4):367-78.
• Mojcik CF, Levy JH. Aprotinin and the systemic inflammatory response after cardiopulmonary bypass. Ann Thorac Surg. 2001;71(2):745-54.
• Moura HV, Pomerantzeff PMA, Gomes WJ. Síndrome da resposta inflamatória sistêmica na circulação extracorpórea: papel das interleucinas. Rev Bras Cir Cardiovasc. 2001;16(4):376-87.
• Kirschner RE, Fantini GA. Role of iron and oxygen-derived free radicals in ischemia-reperfusion injury. J Am Coll Surg. 1994;179(1):103-17
• Mitchell RN, Kumar V, Abbas AK, Fausto N. Inflamação aguda e crônica. In: Robbins & Cotran: fundamentos de patologia. 7ª ed. Rio de Janeiro: Elsevier; 2006. p. 29-54.
• Grisham, M.B, Hernandez, L.A, and Granger, D.N.: Xanthine oxidase and neutrophil infiltration in intestinal ischemia. Am. J. Physiol, 1986;251, G567–G574.
• Granger, D.N, Rutili G, and McCord, J.M: Superoxide radicals in feline intestinal ischemia. Gastroenterology, 1981;81, 22–9.
• Makoto Sasaki and Takashi John: Oxidative Stress and Ischemia-Reperfusion Injury in Gastrointestinal Tract and Antioxidant, Protective Agents. J. Clin. Biochem. Nutr, 2007;40,1–12.
• Parks, D. A. and Granger, D.N: Xanthine oxidase: biochemistry, distribution and physiology. Acta. Physiol. Scand. Suppl. 1986;548, 87–99.
• Harisch, G, Kretschmer, M, Richter, T, and Pickel, M: Investigations on the influence of copper succinate on the production of superoxide anion radicals by bovine small intestinal mucosa cells. Zentralbl. Veterinarmed A, 1989;36, 576–84.
• Schoenberg, M.H, Fredholm, B.B., Haglund, U., Jung, H., Sellin, D., Younes, M., and Schildberg, F.W.: Studies on the oxygen radical mechanism involved in the small intestinal reperfusion damage. Acta. Physiol. Scand, 1985;124, 581–9.
• Menguy, R, Desbaillets, L, and Masters, Y.F: Mechanism of stress ulcer: influence of hypovolemic shock on energy metabolism in the gastric mucosa. Gastroenterology, 1974;66:46–55.
• Robinson, J.W, Mirkovitch, V, Winistorfer, B., and Saegesser, F.: Response of the intestinal mucosa to ischaemia. Gut, 1981;22:512–27.
• Albrecht EW, Stegeman CA, Heeringa P, Henning RH, van Goor H: Protective role of endothelial nitric oxide synthase. J Pathol 2003;199(1):8–17.
• QuXW, Wang H, De Plaen IG, Rozenfeld RA, HsuehW: Neuronal nitric oxide synthase (NOS) regulates the expression of inducible NOS in rat small intestine via modulation of nuclear factor kapa B. FASEB J.2001;15(2):439–46.
• Salzman AL: Nitric oxide in the gut. New Horiz 1995;3(2):352–64.
• Kubes P and McCafferty DM: Nitric oxide and intestinal inflammation. Am J Med.2000;109(2):150–8.
• Suzuki Y, Deitch EA, Mishima S, Lu Q, Xu D: Inducible nitric oxide synthase gene knockout mice have increased resistance to gut injury and bacterial translocation after an intestinal ischemiareperfusion injury. Crit Care Med. 2000 28(11):3692–6.
• Wink DA, Hanbauer I, Krishna MC, DeGraff W, Gamson J, Mitchell JB: Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species. Proc Natl Acad Sci USA. 1993;90(21):9813–7.
• Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hyroxyl radical production by peroxynitrite: implications for endothelial inyury from nitric oxide and superoxide. Proc Natl Acad Sci USA. 1990;87: 1620-4.
• Sekhon B, Sekhon C, Khan M, Patel SJ, Singh I, Singh AK. N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia. Brain Res. 2003;971:1-8.
• Attuwaybi BO, Kozar RA, Moore-Olufemi SD, Sato N, Hassoun HT, Weisbrodt NW, Moore FA. Heme oxygenase-1 induction by hemin protects against gut ischemia/reperfusion injury. J Surg Res. 2004;118: 53-7.
• Janssen-Heininger YM, Poynter ME, and Baeuerle PA. Recent advances towards understandin redox mechanisms in the activation of nuclear factor kappa B. Free Radic Biol Med 2000;28:1317-27.
• Zou L, Attuwaybi B, Kone BC. Effects of NF-kappa B inhibition on mesenteric ischemia-reperfusion injury. Am J Physiol. 2003;284: G713-21.
• P.R. Maroko, C.B. Carpenter, et al, Reduction by cobra venom factor of myocardial necrosis after coronary artery occlusion, J. Clin. Invest. 1978;61(3):661–70.
• Yoshida WB. Radicais livres na síndrome da isquemia e reperfusão. Cir Vasc Angiol. 1996;12: 82-95.