Scleral lens for ocular surface disease

Abstract

Scleral rigid gas-permeable (RGP) lenses play an important and underappreciated role in the treatment of ocular surface disease. This review provides an update on scleral rigid
gas-permeable lenses in the therapy of ocular surface disease (OSD). Several large cohort studies and case series have been published since 2008 that report on the use of scleral
RGP lenses in the treatment of ocular surface disease as a sub-group of corneal disease, or in specific diseases such as Stevens-Johnson syndrome and ocular chronic graft-versushost disease. In addition, there are case reports detailing the treatment with scleral lenses in OSD of specific etiology such as herpes zoster, limbal stem cell deficiency or ocular cicatricial pemphigoid. Two case series were published showing innovative utility of scleral RGP lenses in the management of OSD after glaucoma surgery and for drug delivery for corneal neovascularization. Reports continue to emerge on the impact of scleral RGP lenses in the treatment of patients with ocular surface disease. Advances in lens design and fitting techniques make scleral RGP lenses a practical option for a rising number and variety of patients with corneal disease. Clinicians who treat patients with ocular surface disease should be aware of scleral RGP lenses as a method to treat OSD.

Keywords

• Scleral lens
• Ocular surface disease
• Contact lens
• Stevens-Johnson syndrome
• Graft-versus-host disease
• Limbal stem cell deficiency

References

1. Ezekiel, D., 1983. Gas permeable haptic lenses. British Contact Lens Association. 6, 158-161.
2. Fick, A.E., 1997. A contact lens. 1888. Arch Ophthalmol. 115, 120-121.
3. Grover, S., Jacobs, D. S., Colby, K.A., 2010. Boston Ocular Surface Prosthesis for persistent epitheliopathy after treatment of conjunctival melanoma. Cornea. 29, 459-461.
4. Gumus, K., Gire, A., Pflugfelder, S.C., 2010. The successful use of Boston ocular surface prosthesis in the treatment of persistent corneal epithelial defect after herpes zoster ophthalmicus. Cornea. 29, 1465-1468.
5. Gumus, K., Gire, A., Pflugfelder, S.C., 2011. The impact of the Boston ocular surface prosthesis on wavefront higher-order aberrations. Am. J. Ophthalmol. 151, 682-690.
6. Gungor, I., Schor, K., Rosenthal, P., Jacobs, D.S., 2008. The Boston Scleral Lens in the treatment of pediatric patients. J AAPOS. 12, 263-267.
7. Jacobs, D.S., 2008. Update on scleral lenses. Curr. Opin. Ophthalmol. 19, 298-301.
8. Jacobs, D.S., Rosenthal, P., 2007. Boston scleral lens prosthetic device for treatment of severe dry eye in chronic graft-versus-host disease. Cornea. 26, 1195-1199.

9. Lim, M., Jacobs, D.S., Rosenthal, P., Carrasquillo, K.G., 2009. The Boston Ocular Surface Prosthesis as a novel drug delivery system for bevacizumab. Semin. Ophthalmol. 24, 149-155.
10. Lyons, C.J., Buckley, R.J., Pullum, K., Sapp, N., 1989. Development of the gas-permeable impression-moulded scleral contact lens. A preliminary report. Acta Ophthalmol. Suppl. 192, 162-164.
11. Pearson, R.M., 2007. Karl Otto Himmler, manufacturer of the first contact lens. Cont Lens Anterior Eye. 30, 11-16.
12. Pullum, K., Buckley, R., 2007. Therapeutic and ocular surface indications for scleral contact lenses. Ocul. Surf. 5, 40-48.
13. Rathi, V.M., Mandathara, P.S., Dumpati, S., Vaddavalli, P.K., Sangwan, V.S., 2011. Boston ocular surface prosthesis: An Indian experience. Indian J. Ophthalmol. 59, 279-281.
14. Romero-Rangel, T., Stavrou, P., Cotter, J., Rosenthal, P., Baltatzis, S., Foster, C.F., 2000. Gas-permeable scleral contact lens therapy in ocular surface disease. Am. J. Ophthalmol. 130, 25-32.
15. Russo, P. A., Bouchard, C.S., Galasso, J.M., 2007. Extended-wear silicone hydrogel soft contact lenses in the management of moderate to severe dry eye signs and symptoms secondary to graft-versus-host disease. Eye Contact Lens. 33, 144-147.
16. Schein, O.D., Rosenthal, P., Ducharme, C., 1990. A gas-permeable scleral contact lens for visual rehabilitation. Am. J. Ophthalmol. 109, 318322.
17. Schornack, M.M., 2011. Limbal stem cell disease: management with scleral lenses. Clin. Exp. Optom. 94, 592-594.
18. Schornack, M.M., Baratz, K.H., 2009. Ocular cicatricial pemphigoid: the role of scleral lenses in disease management. Cornea. 28, 1170-1172.
19. Schornack, M.M., Baratz, K.H., Patel, S.V., Maguire, L.J., 2008. Jupiter scleral lenses in the management of chronic graft-versus-host disease. Eye Contact Lens. 34, 302-305.
20. Severinsky, B., Millodot, M., 2010. Current applications and efficacy of scleral contact lenses - a retrospective stduy. J. Optom. 3, 158-163.
21. Stason, W.B., Razavi, M., Jacobs, D.S., Shepard, D.S., Suaya, J.A., Johns, L., Rosenthal, P., 2010. Clinical benefits of the Boston Ocular Surface Prosthesis. Am. J. Ophthalmol. 149, 54-61.
22. Takahide, K., Parker, P.M., Wu, M., Hwang, W.Y., Carpenter, P.A., Moravec, C., Stehr, B., Martin, P.J., Rosenthal, P., Forman, S.J., Flowers, M.E., 2007. Use of fluid-ventilated, gas-permeable scleral lens for management of severe keratoconjunctivitis sicca secondary to chronic graft-versus-host disease. Biol. Blood Marrow Transplant. 13, 1016-1121.
23. Tanhehco, T., Jacobs, D.S., 2010. Technological advances shaping scleral lenses: the Boston ocular surface prosthesis in patients with glaucoma tubes and trabeculectomies. Semin. Ophthalmol. 25, 233-238.
24. Tougeron-Brousseau, B., Delcampe, A., Gueudry, J., Vera, L., Doan, S., Hoang-Xuan, T., Muraine, M., 2009. Vision-related function after scleral lens fitting in ocular complications of Stevens-Johnson syndrome and toxic epidermal necrolysis. Am. J. Ophthalmol. 148, 852-859.
25. Visser, R., 1990. An innovative therapeutic scleral lens for various pathologies [in Dutch]. Nederlands Tijdschrift voor Optometrie en Contactologie. 3, 10-14.