Şarbon

Year 2012, , 155 - 162, 06.02.2013

Aziz Öğütlü

https://doi.org/10.5835/jecm.omu.29.s3.011

Abstract

Şarbon ot yiyen hayvanlardan insanlara bulaşan bir zoonozdur. Bu hastalık ülkemizde özellikle kırsal alanlarda hayvancılık yapanlarda görülmektedir. En sık deri şarbonu görülmektedir. Hastalığın tedavisinde yıllardır penisilin kullanılmaktadır. Ancak son yıllarda penisiline dirençli kökenlerle meydana getirilen biyoterörizm ataklarında siprofloksasin önerilmektedir. Bu derlemede, yeniden önem kazanan şarbona ait klasik bilgilerin yanında, şarbonun biyoterörizm nedenli özellikleri de güncel literatürler eşliğinde gözden geçirilmiştir

Keywords

Şarbon, Bacillus anthracis, Deri şarbonu, Akciğer şarbonu, Gastrointestinal şarbon, Biyoterörizm

References

• Abramova, F., Grinberg, L., Yampolskaya, O., Walker, D.H., 1993. Pathology of inhalational anthrax in 42 cases from the Sverdlovsk outbreak of 1979. Proc. Natl. Acad. Sci. U. S. A. 90, 2291-2294.
• Baldari, C.T., Tonello, F., Paccani, S.R., Montecucco, C., 2006. Anthrax toxins: A paradigm of bacterial immune suppression. Trends Immunol. 27, 434-440.
• Bartlett, J.G., Inglesby, T.V., Jr., Borio, L., 2002. Management of anthrax. Clin. Infect. Dis. 35, 851-858.
• Beatty, M.E., Ashford D.A., Griffin P.M., Tauxe, R.V., Sobel, J., 2003. Gastrointestinal anthrax. Arch. Intern. Med. 163, 2527-2531.
• Brookmeyer, R., Johnson, E., Bollinger, R., 2003. Modeling the optimum duration of antibiotic prophylaxis in an anthrax outbreak. Proc. Natl. Acad. Sci. U.S.A. 100, 10129-10132.
• Carter, T., 2004. The dissemination of anthrax from imported wool: Kidderminster 1900-1914. Occup. Environ. Med. 61,103-107.
• Coker, P., Smith, K., Hugh-Jones, M., 2002. Antimicrobial susceptibilities of diverse Bacillus anthracis isolates. Antimicrob. Agents Chemoth. 46, 3843-3845.
• Doganay, M., Almac, A., Hanagasi, R., 1986. Primary throat anthrax. Scand. J. Infect. Dis. 18, 415-419.
• Doğanay, M., Eşel, D., 2008 . Bacillus anthracis ve diğer bacillus türleri. In: Topçu AW, Söyletir G, Doğanay M (eds). Enfeksiyon Hastalıkları ve Mikrobiyolojisi 3th ed. Nobel Tıp Kitabevi İstanbul. 2101-2114.
• Doğanay, M., 2009. İnsanlarda şarbon. In: Doğanay M, Altıntaş N (eds). Zoonozlar. Hayvanlardan İnsanlara Bulaşan Enfeksiyonlar. Bilimsel Tıp Yayınevi Ankara, 37-51.
• Doganay, M., Metan, G., 2009. Human anthrax in Turkey from 1990 to 2007. Vector Borne Zoonotic Dis. 9, 131-140.
• Doust, J., Sarkarzadeh, A., Kavoossi, K., 1968. Corticosteroid in treatment of malignant edema of chest wall and neck (anthrax). Dis. Chest. 53, 773-774.
• Gold, H., 1955. Anthrax: A report of one hundred seventeen cases. AMA Arch. Intern. Med. 96, 387-396.
• Grabenstein, J., 2008. Vaccines: Countering anthrax-vaccines and immunoglobulins. Clin. Infect. Dis. 46, 129-136.
• Haight, T., 1952. Anthrax meningitis: Review of the literature and report of two cases with autopsies. Am. J. Med. Sci. 224, 57-69.
• Holty, J.E., Bravata, D.M., Liu, H., Olshen, R.A., McDonald, K.M., Owens, D.K., 2006. Systematic review: A century of inhalational anthrax cases from 1900 to 2005. Ann. Intern. Med. 144, 270-280.
• IDSA, 2011. Infectious Diseases Society of America: Bacillus anthracis (Anthrax). Available at Access October 08, 2011 http://biodefense. idsociety.org/idsa/bt/anthrax/biofacts/anthrax_agent.html
• Jay, V., 2001. The legacy of Robert Koch. Arch. Pathol. Lab. Med. 125, 1148-1149.
• Karahocagil, M.K., Akdeniz, N., Akdeniz, H., Calka, O., Karsen, H., Bilici, A., Bilgili, S.G., Evirgen, O., 2008. Cutaneous anthrax in Eastern Turkey: A review of 85 cases. Clin. Exp. Dermatol. 33, 406-411.
• Kaya, A., Tasyaran, M.A., Erol, S., Ozkurt, Z., 2002. Anthrax in adults and children: A review of 132 cases in Turkey. Eur. J. Clin. Microbiol. Infect. Dis. 21, 258-261.
• Deneysel ve Klinik Tıp Dergisi - Journal of Experimental and Clinical Medicine 29 (2012) S155-S162
• Leblebicioglu, H., Turan,D., Eroglu, C., Esen, S., Sunbul, M., Bostanci, F., 2006. A cluster of anthrax cases including meningitis Trop. Doct. 36, 51-53.
• Martin, G.J., Friedlander, A.M., 2010. Bacillus anthracis (Anthrax). In: Mandell GL, Bennet JE, Dolin R (eds). Principles and Practice of Infec- tious Diseases (7th ed).Churchill Livingstone Elsevier Philadelphia. 2715-2725.
• Metan, G., Doğanay, M., 2009. The antimicrobial susceptibility of Bacillus anthracis isolated from human cases: A review of the Turkish litera- ture. Turkiye Klinikleri J. Med. Sci. 29, 229-235.
• Metan, G., Uysal, B., Coşkun, R., Perçin, D., Doğanay, M., 2009. Anthrax meningoencephalitis: A case report and review of Turkish literature. Mikrobiyol. Bul. 43, 671-676.
• Quinn, C.P., Dull, P.M., Semenova, V., Li, H., Crotty, S., Taylor, T.H., Steward-Clark, E., Stamey, K.L., Schmidt, D.S., Stinson, K.W., Freeman, A.E., Elie, C.M., Martin, S.K., Grene, C., Aubert, R.D., Gliwell, J., Perkins, B.A., Ahmed, R., Stephens, D.S., 2004. Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax. J. Infect. Dis. 190, 1228-1236.
• Redmond, C., Pearce, M.J., Manchee, R.J., Berdal, B.P., 1998. Deadly relic of the Great War. Nature. 393, 747-748.
• Roche, K., Chang, M., Lazarus, H., 2001. Cutaneous anthrax infection. New Engl. J. Med. 345, 1611.
• Sejvar, J., Tenover, F., Stephens, D., 2005. Management of anthrax meningitis. Lancet Infect. Dis. 5, 287-295.
• Sherer, K., Li, Y., Cui, X., 2007. Lethal and edema toxins in the pathogenesis of Bacillus anthracis septic shock. Am. J. Respir. Crit. Care Med. 175, 211-221.
• Sirisanthana, T., Brown, A., 2002. Anthrax of the gastrointestinal tract. Emerg. Infect. Dis. 8, 649-651.
• Stern, E.J., Uhde, K.B., Shadomy, S.V., Messonnier, N., 2008. Conference report on public health and clinical guidelines for anthrax. Emerg. Infect. Dis. 14. doi: 10.3201/eid1404.070969.
• Walsh, J.J., Pesik, N., Quinn, C.P., Urdaneta, V., Dykewicz, C.A., Boyer, A.E., Guarner, J., Wilkins, P., Norville, K.J., Barr, J.R., Zaki, S.R., Patel, J.B., Reagen, S.P., Pirkle, J.L., Treadwell, T.A., Messonnier, N.R., Rotz, L.D., Meyer, R.F., Stephens, D.S., 2007. A case of naturally acquired inhalation anthrax: Clinical care and analyses of anti–protective antigen immunoglobulin G and lethal factor. Clin. Infect. Dis. 44, 968-971.
• WHO, 2008. Anthrax in Human and Animals, 4th edition. World Health Organization http://www.who.int/csr/resources/publications/anthrax_ webs.pdf.