Bilateral central retinal vein occlusion in non-Hodgkin lymphoma and the effects of intravitreal bevacizumab injection

Abstract

The purpose of this study is to report bilateral central retinal vein occlusion in a patient with non-Hodgkin lymphoma and the effects of intravitreal bevacizumab injection. This is a case report of a patient seen and treated in the ophthalmology department of Ondokuz Mayıs University Medical Faculty. Bilateral central retinal vein occlusion was observed in the patient because of hyperviscosity due to non-Hodgkin lymphoma which resulted in decreased visual acuity and increased macular thickness. Bilateral intravitreal bevacizumab injection increased best corrected visual acuity increased and reduced intraretinal, subretinal edema markedly. A hyperviscosity syndrome or inflammatory condition should be suspected when a patient, less than 50 years, has bilateral and simultaneous central retinal vein occlusion. Intravitreal bevacizumab injection is as an effective treatment for intraretinal and subretinal edema in central retinal vein occlusion secondary to non-Hodgkin lymphoma.

Keywords

• Non-Hodgkin lymphoma
• Central retinal vein occlusion
• Intravitreal bevacizumab
• Hyperviscosity syndrome

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