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Minimally invasive surgery modalities in the treatment of esophagial cancers

Year 2012, , 251 - 256, 07.05.2013
https://doi.org/10.5835/jecm.omu.29.s4.010

Abstract

Malignant tumours of esophagus have an increasing frequency in the population with a high mortality. Surgery is the most important choice of treatment modality in the first 3 stages of the disease. In the open surgery methods for esophagial cancers, mortality and morbidity rates are between 5-15% and 30-60% respectively. Due to these high rates for mortality and morbidity, minimally invasive surgery (MIS) gained great importance in the treatment of these patients. Patient selection in esophagial cancer treatment by using MIS is very important. These modalities can be used for lesions located in middle-distal portion of esophagus. Tumours should not have any invasion to adjacent structures, widespread lymph node invasions and should be staged between
T1-3 N0-1. Lateral decubitus and also prone position can be used for MIS. There are still no controlled randomised studies comparing MIS to open surgery for esophagial cancers. But retrospective series show that oncologic results are similar and postoperative complications are better in MIS groups. On the current daily practice MIS are done by experienced institutuions and surgical groups. In the future MIS will be used more commonly in treatment of esophagial cancers by improvement in invasive skills and infrastructures in the institutions

References

  • Akiyama, S., Kodera, Y., Sekiguchi, H., Kasai, Y., Kondo, K., Ito, K., Takagi, H., 1998. Preoperative embolization therapy for esophageal opera- tion. J. Surg. Oncol. 69, 219-223.
  • Atkins, B.Z., Fortes, D.L., Watkins, K.T., 2007. Analysis of respiratory complications after minimally invasive esophagectomy: Preliminary observation of persistent aspiration risk. Dysphagia. 22, 49-54.
  • Azagra, J.S., Ceuterick, M., Goergen, M., Jacobs, D., Gilbart, E., Zaouk, G., Carlier, E., Lejeune, P., Alle, J.L., Mathys, M., 1993. Thoracoscopy in oesophagectomy for oesophageal cancer. Br. J. Surg. 80, 320-321.
  • Bhat, M.A., Dar, M.A., Lone, G.N., Dar, A.M., 2006. Use of pedicled omentum in esophagogastric anastomosis for prevention of anastomotic leak. Ann. Thorac. Surg. 82, 1857-1862.
  • Biere, S.S., Cuesta, M.A., van der Peet, D.L., 2009. Minimally invasive versus open esophagectomy for cancer: A systematic review and meta- analysis. Minerva Chir. 64, 121-133.
  • Bizekis, C., Kent M.S., Luketich, J.D., Buenaventura, P.O., Landreneau, R.J., Schuchert, M.J., Alvelo-Rivera, M., 2006. Initial experience with minimally invasive Ivor Lewis esophagectomy. Ann. Thorac. Surg. 82, 406-407.
  • Braghetto, I., Csendes, A., Cardemil, G., Burdiles, P., Korn, O., Valladares, H., 2006. Open transthoracic or transhiatal esophagectomy versus minimally invasive esophagectomy in terms of morbidity, mortality and survival. Surg. Endosc. 20, 1681-1686.
  • Dallemagne, B., Weerts, J.M., Jehaes, C., Markiewicz, S., Lombard, R., 1991. Laparoscopic Nissen fundoplication: Preliminary report Surg. Laparosc. Endosc. 1, 138-143.
  • Dapri, G., Himpens, J., Cadière, G.B., 2006. Robot-assisted thoracoscopic esophagectomy with the patient in the prone position.J Laparoendosc Adv Surg Tech A. 16, 278-285.
  • Decker, G., Coosemans, W., De Leyn, P., Decaluwé, H., Nafteux, P., Van Raemdonck, D., Lerut, T., 2009. Minimally invasive esophagectomy for cancer. Eur. J. Cardiothorac. Surg. 35, 13-21.
  • Dexter, S.P., Martin, I.G., McMahon, M.J., 1996. Radical thoracoscopic esophagectomy for cancer. Surg. Endosc. 10, 147-151.
  • Earlam, R., Cunha-Melo, J.R., 1980. Oesophageal squamous cell carcinoma: I. A critical review of surgery. Br. J. Surg. 67, 381-390.
  • Enestvedt, C.K., Perry, K.A., Kim, C., McConnell, P.W., Diggs, B.S., Vernon, A., O’Rourke, R.W., Luketich, J.D., Hunter, J.G., Jobe, B.A., 2010. Trends in the management of esophageal carcinoma based on provider volume: Treatment practices of 618 esophageal surgeons. Dis. Esophagus. 23, 136-144.
  • Fabian, T., Martin, J., Katigbak, M., McKelvey, A.A., Federico, J.A., 2008. Thoracoscopic esophageal mobilization during minimally invasive esophagectomy: A head-to-head comparison of prone versus decubitus positions. Surg. Endosc. 22, 2485-2491.
  • Gemmill, E.H., McCulloch, P., 2007. Systematic review of minimally invasive resection for gastro-oesophageal cancer. Br. J. Surg. 94, 1461- 1467.
  • Gossot, D., Fourquier, P., Celerier, M., 1993. Thoracoscopic esophagectomy: Technique and initial results. Ann. Thorac. Surg. 56, 667-670.
  • Grewal, N., El-Badawi, K., Nguyen, N.T., 2009. Minimally invasive ivor lewis esophagectomy for the management of iatrogenic esophageal perforation in a patient with esophageal cancer. Surg. Technol. Int. 18, 82-85.
  • Hamouda, A.H., Forshaw, M.J., Tsigritis, K., Jones, G.E., Noorani, A.S., Rohatgi, A., Botha, A.J., 2010. Perioperative outcomes after transition from conventional to minimally invasive Ivor-Lewis esophagectomy in a specialized center. Surg. Endosc. 24, 865-869.
  • Hinojosa, M.W., Mailey, B.A., Smith, B.R., Reavis, K.M., Nguyen, N.T., 2009. Minimally invasive Ivor-Lewis esophagogastrectomy for gastric cardia cancer. Surg. Endosc. 23, 2656.
  • Hoppo, T., Jobe, B.A., Hunter, J.G., 2011. Minimally invasive esophagectomy: The evolution and technique of minimally invasive surgery for esophageal cancer. World J. Surg. 35, 1454-1463.
  • Hölscher, A.H., Schneider, P.M., Gutschow, C., Schröder, W., 2007. Laparoscopic ischemic conditioning of the stomach for esophageal replace- ment. Ann. Surg. 245, 241-246.
  • Law, S.Y., Fok, M., Wei, W.I., Lam, L.K., Tung, P.H., Chu, K.M., Wong, J., 2000. Thoracoscopic esophageal mobilization for pharyngolaryn- goesophagectomy. Ann. Thorac. Surg. 70, 418-422.
  • Law, S., Wong, J., 2005. Current management of esophageal cancer. J. Gastrointest. Surg. 9, 291-310.
  • Law, S., Kwong, D.L., Kwok, K.F., Wong, K.H., Chu, K.M., Sham, J.S., Wong, J., 2003. Improvement in treatment results and long-term sur- vival of patients with esophageal cancer: Impact of chemoradiation and change in treatment strategy. Ann. Surg. 238, 339-348.
  • Luketich, J.D., Alvelo-Rivera, M., Buenaventura, P.O., Christie, N.A., McCaughan, J.S., Litle, V.R., Schauer, P.R., Close, J.M., Fernando, H.C., 2003. Minimally invasive esophagectomy: Outcomes in 222 patients. Ann. Surg. 238, 486-495.
  • Mehran, R.J., 2008. Minimally invasive surgical treatment of esophageal carcinoma. Gastrointest. Cancer Res. 2, 283-286.
  • Nagpal, K., Ahmed, K., Vats, A., Yakoub, D., James, D., Ashrafian, H., Darzi, A., Moorthy, K., Athanasiou, T., 2010. Is minimally invasive sur- gery beneficial in the management of esophageal cancer? A meta-analysis. Surg. Endosc. 24, 1621-1629.
  • Ng, C.S., Wan, S., Hui, C.W., Wan, I.Y., Lee, T.W., Underwood, M.J., Yim, A.P., 2007. Video-assisted thoracic surgery lobectomy for lung cancer is associated with less immunochemokine disturbances than thoracotomy. Eur. J. Cardiothorac. Surg. 31, 83-87.
  • Nguyen, T.N., Hinojosa, M.W., Smith, B.R., Gray, J., Reavis, K.M., 2008. Thoracoscopic construction of an intrathoracic esophagogastric anas- tomosis using a circular stapler: transoral placement of the anvil. Ann. Thorac. Surg. 86, 989-992.
  • Nguyen, N.T., Hinojosa, M.W., Smith, B.R., Chang, K.J., Gray, J., Hoyt, D., 2008. Minimally invasive esophagectomy: Lessons learned from 104 operations. Ann. Surg. 248, 1081-1091.
  • Orringer, M.B., Marshall, B., Chang, A.C., Lee, J., Pickens, A., Lau, C.L., 2007. Two thousand transhiatal esophagectomies: Changing trends, lessons learned. Ann. Surg. 246, 363-374.
  • Osugi, H., Takemura, M., Higashino, M., Takada, N., Lee, S., Ueno, M., Tanaka, Y., Fukuhara, K., Hashimoto, Y., Fujiwara, Y., Kinoshita, H., 2003. Learning curve of video-assisted thoracoscopic esophagectomy and extensive lymphadenectomy for squamous cell cancer of the tho- racic esophagus and results. Surg. Endosc. 17, 515-519.
  • Palanivelu, C., Prakash, A., Senthilkumar, R., Senthilnathan, P., Parthasarathi, R., Rajan, P.S., Venkatachlam, S., 2006. Minimally invasive esophagectomy: Thoracoscopic mobilization of the esophagus and mediastinal lymphadenectomy in prone position experience of 130 pa- tients. J. Am. Coll Surgeons. 203, 7-16.
  • Parameswaran, R., Veeramootoo, D., Krishnadas, R., Cooper, M., Berrisford, R., Wajed, S., 2009. Comparative experience of open and mini- mally invasive esophagogastric resection. World J. Surg. 33, 1868-1875.
  • Petri, R., Zuccolo, M., Brizzolari, M., Rossit, L., Rosignoli, A., Durastante, V., Petrin, G., De Cecchis, L., Sorrentino, M., 2011. Minimally in- vasive esophagectomy: Thoracoscopic esophageal mobilization for esophageal cancer with the patient in prone position. Surg. Endosc. 26, 1102-1107.
  • Smithers, B.M., Gotley, D.C., Martin, I., Thomas, J.M., 2007. Comparison of the outcomes between open and minimally invasive esophagec- tomy. Ann. Surg. 245, 232-240.
  • Smithers, BM., Gotley, D.C., McEwan, D., Martin, I., Bessell, J., Doyle, L., 2001. Thoracoscopic mobilization of the esophagus. A 6 year experi- ence. Surg. Endosc. 15, 176-182.
  • Swanson, S.J., Batirel, H.F., Bueno, R., Jaklitsch, M.T., Lukanich, J.M., Allred, E., Mentzer, S.J., Sugarbaker, D.J., 2001. Transthoracic esophagectomy with radical mediastinal and abdominal lymph node dissection and cervical esophagogastrostomy for esophageal carcinoma. Ann. Thorac. Surg. 72, 1918-1925.
  • Tapias, L.F., Morse, C.R., 2011. A preliminary experience with minimally invasive Ivor Lewis esophagectomy. Dis. Esophagus. 25,449-455.
  • Varela, E., Reavis, K.M., Hinojosa, M.W., Nguyen, N., 2008. Laparoscopic gastric ischemic conditioning prior to esophagogastrectomy: Tech- nique and review. Surg. Innov. 15, 132-135.
  • Watson, T.J., 2008. Robotic esophagectomy: Is it an advance and what is the future? Ann. Thorac. Surg. 85, 757-759.
  • Yamamoto, S., Kawahara, K., Maekawa, T., Shiraishi, T., Shirakusa, T., 2005. Minimally invasive esophagectomy for stage I and II esophageal cancer. Ann. Thorac. Surg. 80, 2070-2075.
  • Zhou, J., Chen, H., Lu, J.J., Xiang, J., Zhang, Y., Hu, H., Zhou, X., Luo, X., Yang, F., Tam, J., 2009. Application of a modified McKeown proce- dure (thoracoscopic esophageal mobilization three-incision esophagectomy) in esophageal cancer surgery: Initial experience with 30 cases. Dis. Esophagus. 22, 687-693.

Özofagus kanserleri tedavisinde minimal invaziv cerrahi uygulamaları

Year 2012, , 251 - 256, 07.05.2013
https://doi.org/10.5835/jecm.omu.29.s4.010

Abstract

Özofagus kanserleri toplumda giderek daha sık görülen yüksek mortaliteyle seyreden bir hastalıktır. Cerrahi özofagus kanserlerinin ilk üç evresinde en önemli tedavi yöntemidir. Açık yapılan özofagus kanser mortalite ve morbidite oranları sırasıyla % 5-15 ve % 30- 60 arasında değişmektedir. Bu yüksek mortalite ve morbidite nedeniyle minimal invazif cerrahi (MİC) önem kazanmıştır. Özofagus kanseri için uygulanan MİC’de hasta seçimi çok önemlidir. Bu yöntemler orta-distal özofagusta yer alan, çevreye invazyonu veya yaygın lenf nodu metastazı bulunmayan evre T1-3 N0-1 tümörlerde uygulanabilir. MİC’de lateral dekübitus pozisyon kullanılabildiği gibi, yüz üstü pozisyonda kullanılmaktadır. MİC ile açık özofajektomi sonuçlarını kıyaslayan randomize kontrollü bir çalışma henüz yoktur, ancak mevcut retrospektif vaka serilerinden çıkan sonuçlara göre MİC’nin onkolojik sonuçlar açısından konvasiyonel özofajektomiye benzer, postoperatif komplikasyonlar açısından ise daha iyi sonuçlara sahip olduğu belirtilmektedir. Halihazırda özofagus kanserinde MİC ciddi deneyime sahip ekipler tarafından uygulanmaktadır. MİC girişim becerilerinin ve alt yapıların geliştirilmesi ile daha sık uygulanabilecektir

References

  • Akiyama, S., Kodera, Y., Sekiguchi, H., Kasai, Y., Kondo, K., Ito, K., Takagi, H., 1998. Preoperative embolization therapy for esophageal opera- tion. J. Surg. Oncol. 69, 219-223.
  • Atkins, B.Z., Fortes, D.L., Watkins, K.T., 2007. Analysis of respiratory complications after minimally invasive esophagectomy: Preliminary observation of persistent aspiration risk. Dysphagia. 22, 49-54.
  • Azagra, J.S., Ceuterick, M., Goergen, M., Jacobs, D., Gilbart, E., Zaouk, G., Carlier, E., Lejeune, P., Alle, J.L., Mathys, M., 1993. Thoracoscopy in oesophagectomy for oesophageal cancer. Br. J. Surg. 80, 320-321.
  • Bhat, M.A., Dar, M.A., Lone, G.N., Dar, A.M., 2006. Use of pedicled omentum in esophagogastric anastomosis for prevention of anastomotic leak. Ann. Thorac. Surg. 82, 1857-1862.
  • Biere, S.S., Cuesta, M.A., van der Peet, D.L., 2009. Minimally invasive versus open esophagectomy for cancer: A systematic review and meta- analysis. Minerva Chir. 64, 121-133.
  • Bizekis, C., Kent M.S., Luketich, J.D., Buenaventura, P.O., Landreneau, R.J., Schuchert, M.J., Alvelo-Rivera, M., 2006. Initial experience with minimally invasive Ivor Lewis esophagectomy. Ann. Thorac. Surg. 82, 406-407.
  • Braghetto, I., Csendes, A., Cardemil, G., Burdiles, P., Korn, O., Valladares, H., 2006. Open transthoracic or transhiatal esophagectomy versus minimally invasive esophagectomy in terms of morbidity, mortality and survival. Surg. Endosc. 20, 1681-1686.
  • Dallemagne, B., Weerts, J.M., Jehaes, C., Markiewicz, S., Lombard, R., 1991. Laparoscopic Nissen fundoplication: Preliminary report Surg. Laparosc. Endosc. 1, 138-143.
  • Dapri, G., Himpens, J., Cadière, G.B., 2006. Robot-assisted thoracoscopic esophagectomy with the patient in the prone position.J Laparoendosc Adv Surg Tech A. 16, 278-285.
  • Decker, G., Coosemans, W., De Leyn, P., Decaluwé, H., Nafteux, P., Van Raemdonck, D., Lerut, T., 2009. Minimally invasive esophagectomy for cancer. Eur. J. Cardiothorac. Surg. 35, 13-21.
  • Dexter, S.P., Martin, I.G., McMahon, M.J., 1996. Radical thoracoscopic esophagectomy for cancer. Surg. Endosc. 10, 147-151.
  • Earlam, R., Cunha-Melo, J.R., 1980. Oesophageal squamous cell carcinoma: I. A critical review of surgery. Br. J. Surg. 67, 381-390.
  • Enestvedt, C.K., Perry, K.A., Kim, C., McConnell, P.W., Diggs, B.S., Vernon, A., O’Rourke, R.W., Luketich, J.D., Hunter, J.G., Jobe, B.A., 2010. Trends in the management of esophageal carcinoma based on provider volume: Treatment practices of 618 esophageal surgeons. Dis. Esophagus. 23, 136-144.
  • Fabian, T., Martin, J., Katigbak, M., McKelvey, A.A., Federico, J.A., 2008. Thoracoscopic esophageal mobilization during minimally invasive esophagectomy: A head-to-head comparison of prone versus decubitus positions. Surg. Endosc. 22, 2485-2491.
  • Gemmill, E.H., McCulloch, P., 2007. Systematic review of minimally invasive resection for gastro-oesophageal cancer. Br. J. Surg. 94, 1461- 1467.
  • Gossot, D., Fourquier, P., Celerier, M., 1993. Thoracoscopic esophagectomy: Technique and initial results. Ann. Thorac. Surg. 56, 667-670.
  • Grewal, N., El-Badawi, K., Nguyen, N.T., 2009. Minimally invasive ivor lewis esophagectomy for the management of iatrogenic esophageal perforation in a patient with esophageal cancer. Surg. Technol. Int. 18, 82-85.
  • Hamouda, A.H., Forshaw, M.J., Tsigritis, K., Jones, G.E., Noorani, A.S., Rohatgi, A., Botha, A.J., 2010. Perioperative outcomes after transition from conventional to minimally invasive Ivor-Lewis esophagectomy in a specialized center. Surg. Endosc. 24, 865-869.
  • Hinojosa, M.W., Mailey, B.A., Smith, B.R., Reavis, K.M., Nguyen, N.T., 2009. Minimally invasive Ivor-Lewis esophagogastrectomy for gastric cardia cancer. Surg. Endosc. 23, 2656.
  • Hoppo, T., Jobe, B.A., Hunter, J.G., 2011. Minimally invasive esophagectomy: The evolution and technique of minimally invasive surgery for esophageal cancer. World J. Surg. 35, 1454-1463.
  • Hölscher, A.H., Schneider, P.M., Gutschow, C., Schröder, W., 2007. Laparoscopic ischemic conditioning of the stomach for esophageal replace- ment. Ann. Surg. 245, 241-246.
  • Law, S.Y., Fok, M., Wei, W.I., Lam, L.K., Tung, P.H., Chu, K.M., Wong, J., 2000. Thoracoscopic esophageal mobilization for pharyngolaryn- goesophagectomy. Ann. Thorac. Surg. 70, 418-422.
  • Law, S., Wong, J., 2005. Current management of esophageal cancer. J. Gastrointest. Surg. 9, 291-310.
  • Law, S., Kwong, D.L., Kwok, K.F., Wong, K.H., Chu, K.M., Sham, J.S., Wong, J., 2003. Improvement in treatment results and long-term sur- vival of patients with esophageal cancer: Impact of chemoradiation and change in treatment strategy. Ann. Surg. 238, 339-348.
  • Luketich, J.D., Alvelo-Rivera, M., Buenaventura, P.O., Christie, N.A., McCaughan, J.S., Litle, V.R., Schauer, P.R., Close, J.M., Fernando, H.C., 2003. Minimally invasive esophagectomy: Outcomes in 222 patients. Ann. Surg. 238, 486-495.
  • Mehran, R.J., 2008. Minimally invasive surgical treatment of esophageal carcinoma. Gastrointest. Cancer Res. 2, 283-286.
  • Nagpal, K., Ahmed, K., Vats, A., Yakoub, D., James, D., Ashrafian, H., Darzi, A., Moorthy, K., Athanasiou, T., 2010. Is minimally invasive sur- gery beneficial in the management of esophageal cancer? A meta-analysis. Surg. Endosc. 24, 1621-1629.
  • Ng, C.S., Wan, S., Hui, C.W., Wan, I.Y., Lee, T.W., Underwood, M.J., Yim, A.P., 2007. Video-assisted thoracic surgery lobectomy for lung cancer is associated with less immunochemokine disturbances than thoracotomy. Eur. J. Cardiothorac. Surg. 31, 83-87.
  • Nguyen, T.N., Hinojosa, M.W., Smith, B.R., Gray, J., Reavis, K.M., 2008. Thoracoscopic construction of an intrathoracic esophagogastric anas- tomosis using a circular stapler: transoral placement of the anvil. Ann. Thorac. Surg. 86, 989-992.
  • Nguyen, N.T., Hinojosa, M.W., Smith, B.R., Chang, K.J., Gray, J., Hoyt, D., 2008. Minimally invasive esophagectomy: Lessons learned from 104 operations. Ann. Surg. 248, 1081-1091.
  • Orringer, M.B., Marshall, B., Chang, A.C., Lee, J., Pickens, A., Lau, C.L., 2007. Two thousand transhiatal esophagectomies: Changing trends, lessons learned. Ann. Surg. 246, 363-374.
  • Osugi, H., Takemura, M., Higashino, M., Takada, N., Lee, S., Ueno, M., Tanaka, Y., Fukuhara, K., Hashimoto, Y., Fujiwara, Y., Kinoshita, H., 2003. Learning curve of video-assisted thoracoscopic esophagectomy and extensive lymphadenectomy for squamous cell cancer of the tho- racic esophagus and results. Surg. Endosc. 17, 515-519.
  • Palanivelu, C., Prakash, A., Senthilkumar, R., Senthilnathan, P., Parthasarathi, R., Rajan, P.S., Venkatachlam, S., 2006. Minimally invasive esophagectomy: Thoracoscopic mobilization of the esophagus and mediastinal lymphadenectomy in prone position experience of 130 pa- tients. J. Am. Coll Surgeons. 203, 7-16.
  • Parameswaran, R., Veeramootoo, D., Krishnadas, R., Cooper, M., Berrisford, R., Wajed, S., 2009. Comparative experience of open and mini- mally invasive esophagogastric resection. World J. Surg. 33, 1868-1875.
  • Petri, R., Zuccolo, M., Brizzolari, M., Rossit, L., Rosignoli, A., Durastante, V., Petrin, G., De Cecchis, L., Sorrentino, M., 2011. Minimally in- vasive esophagectomy: Thoracoscopic esophageal mobilization for esophageal cancer with the patient in prone position. Surg. Endosc. 26, 1102-1107.
  • Smithers, B.M., Gotley, D.C., Martin, I., Thomas, J.M., 2007. Comparison of the outcomes between open and minimally invasive esophagec- tomy. Ann. Surg. 245, 232-240.
  • Smithers, BM., Gotley, D.C., McEwan, D., Martin, I., Bessell, J., Doyle, L., 2001. Thoracoscopic mobilization of the esophagus. A 6 year experi- ence. Surg. Endosc. 15, 176-182.
  • Swanson, S.J., Batirel, H.F., Bueno, R., Jaklitsch, M.T., Lukanich, J.M., Allred, E., Mentzer, S.J., Sugarbaker, D.J., 2001. Transthoracic esophagectomy with radical mediastinal and abdominal lymph node dissection and cervical esophagogastrostomy for esophageal carcinoma. Ann. Thorac. Surg. 72, 1918-1925.
  • Tapias, L.F., Morse, C.R., 2011. A preliminary experience with minimally invasive Ivor Lewis esophagectomy. Dis. Esophagus. 25,449-455.
  • Varela, E., Reavis, K.M., Hinojosa, M.W., Nguyen, N., 2008. Laparoscopic gastric ischemic conditioning prior to esophagogastrectomy: Tech- nique and review. Surg. Innov. 15, 132-135.
  • Watson, T.J., 2008. Robotic esophagectomy: Is it an advance and what is the future? Ann. Thorac. Surg. 85, 757-759.
  • Yamamoto, S., Kawahara, K., Maekawa, T., Shiraishi, T., Shirakusa, T., 2005. Minimally invasive esophagectomy for stage I and II esophageal cancer. Ann. Thorac. Surg. 80, 2070-2075.
  • Zhou, J., Chen, H., Lu, J.J., Xiang, J., Zhang, Y., Hu, H., Zhou, X., Luo, X., Yang, F., Tam, J., 2009. Application of a modified McKeown proce- dure (thoracoscopic esophageal mobilization three-incision esophagectomy) in esophageal cancer surgery: Initial experience with 30 cases. Dis. Esophagus. 22, 687-693.
There are 43 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Surgery Medical Sciences
Authors

Hasan Fehmi Batırel This is me

H.Volkan Kara This is me

Publication Date May 7, 2013
Submission Date September 26, 2012
Published in Issue Year 2012

Cite

APA Batırel, H. F., & Kara, H. (2013). Özofagus kanserleri tedavisinde minimal invaziv cerrahi uygulamaları. Journal of Experimental and Clinical Medicine, 29(4S), 251-256. https://doi.org/10.5835/jecm.omu.29.s4.010
AMA Batırel HF, Kara H. Özofagus kanserleri tedavisinde minimal invaziv cerrahi uygulamaları. J. Exp. Clin. Med. May 2013;29(4S):251-256. doi:10.5835/jecm.omu.29.s4.010
Chicago Batırel, Hasan Fehmi, and H.Volkan Kara. “Özofagus Kanserleri Tedavisinde Minimal Invaziv Cerrahi Uygulamaları”. Journal of Experimental and Clinical Medicine 29, no. 4S (May 2013): 251-56. https://doi.org/10.5835/jecm.omu.29.s4.010.
EndNote Batırel HF, Kara H (May 1, 2013) Özofagus kanserleri tedavisinde minimal invaziv cerrahi uygulamaları. Journal of Experimental and Clinical Medicine 29 4S 251–256.
IEEE H. F. Batırel and H. Kara, “Özofagus kanserleri tedavisinde minimal invaziv cerrahi uygulamaları”, J. Exp. Clin. Med., vol. 29, no. 4S, pp. 251–256, 2013, doi: 10.5835/jecm.omu.29.s4.010.
ISNAD Batırel, Hasan Fehmi - Kara, H.Volkan. “Özofagus Kanserleri Tedavisinde Minimal Invaziv Cerrahi Uygulamaları”. Journal of Experimental and Clinical Medicine 29/4S (May 2013), 251-256. https://doi.org/10.5835/jecm.omu.29.s4.010.
JAMA Batırel HF, Kara H. Özofagus kanserleri tedavisinde minimal invaziv cerrahi uygulamaları. J. Exp. Clin. Med. 2013;29:251–256.
MLA Batırel, Hasan Fehmi and H.Volkan Kara. “Özofagus Kanserleri Tedavisinde Minimal Invaziv Cerrahi Uygulamaları”. Journal of Experimental and Clinical Medicine, vol. 29, no. 4S, 2013, pp. 251-6, doi:10.5835/jecm.omu.29.s4.010.
Vancouver Batırel HF, Kara H. Özofagus kanserleri tedavisinde minimal invaziv cerrahi uygulamaları. J. Exp. Clin. Med. 2013;29(4S):251-6.