Intracranial meningiomas: Two-years experience of Mustafa Kemal University

Abstract

Meningiomas are the most common type of brain tumors. We have analyzed clinical, radiological and pathological characteristics of meningiomas that were diagnosed and operated in our centre. Twenty three meningioma cases operated in our hospital between 2010-2012 were reviewed retrospectively. Sixteen (69.1%) of cases were female and 7 (30.9%) of cases were male. The age range was 22-75. The most common symptoms of patients were headache, seizure, nausea and vomitting. Localizations of tumors were flax, cortex, sphenoid wing, posterior fossa-tentorium, olphactor, and sulcus. The surgical sizes were graded according to Simpson classification and 16 (69.1%) of cases were Grade 2 and 7 (30.9%) of cases were Grade I. At the histopathological examination; meningotheliomatous type was the most common type followed by fibrous, angiomatous, transitional, psammomatous and atypical types. Meningiomas are usually benign tumors with good prognosis which are often encountered in daily pathology and neurosurgery practice.

Keywords

• Clinic
• Intracranial
• Meningioma
• Pathology

References

1. Alexiou, G.A., Gogou, P., Markoula, S., Kyritsis, A.P., 2010. Management of meningiomas. Clin. Neurol. Neurosurg. 112, 117-182.
2. Chamberlain, M.C., Glantz, M.J., Fadul, C.E., 2007. Recurrent meningioma: Salvage therapy with sandostatin. Neurology. 69, 969-973.
3. Chan, R.C., Thompson, C.B., 1984. Morbidity mortality and quality of life following surgery for intracranial meningiomas: A retrospective study in 257 cases. J. Neurosurg. 60, 52-60.
4. Claus, E.B., Bondy, M.L., Schildkraut, J.M., Wiemels, J.L., Wrensch, M., Black, P.M., 2005. Epidemiology of intracranial meningioma. Neu- rosurg. 57, 1088-1095.
5. Claus, E.B., Calvocoressi, L., Bondy ,M.L., Wrensch, M., Wiemels, J.L., Schildkraut, J.M., 2012. Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females. J. Neurosurg. 118, 649-656.
6. Flickinger, J.C., Kondziolka, D., Maitz, A.H., Lunsford, L.D., 2003. Gamma knife radiosurgery of imaging-diagnosed intracranial meningioma. Int. J. Radiat. Oncol. Biol. Phys. 56, 801-806.
7. Ginsberg, L.E., 1996. Radiology of menigiomas. J. Neurooncol. 29, 229-238.
8. Greenberg, M.S., 2001. Tumor. In: Hand book of Neurosurgery. 5th ed. New-York: Thieme press, 407-410.

9. Karabaglı, P., Gucluer, B., Erdincler, G., Aksoy, N., Barlas, A., 2004. The histopathologic features of 172 meningioma cases. Türkiye Ekopatoloji Dergisi 10, 13-19.
10. Mahmood, A., Caccamo, D.V., Tomecek, F.J., Malik, G.M., 1993. Atypical and malignant meningiomas: A clinicopathological review. Neuro- surgery. 33, 955-963.
11. McCarthy, B.J., Davis , F.G., Freels, S., Surawicz, T.S., Damek, D.M., Grutsch, J., 1998. Factors associated with survival in patients with men- ingioma. J. Neurosurg. 88, 831-839.
12. Moon, H.S., Jung, S., Jang, W.Y., Jung, T.Y., Moon, K.S., Kim, I.Y., 2012. Intracranial meningiomas WHO Grade II: Prognostic implications of clinicopathologic features. J. Korean Neurosurg. Soc. 52, 14-20.
13. Nakasu, S., Fukami, T., Jito, T., Nozaki, K., 2009. Recurrence and regrowth of benign meningiomas. Brain Tumor Pathol. 26, 69-72.
14. Phillips L.E, Longstreth Jr W.T., Koepsell, T., Custer, B.S., Kukull, W.A., van Belle G., 2005. Active and passive cigarette smoking and risk of intracranial meningioma. Neuroepidemiology. 24, 117-122.
15. Ragel, B.T., Jensen, R.L., 2005. Molecular genetics of meningiomas. Neurosurg. Focus. 19, E9.
16. Rohinger, M., Sutherland, G.R., Louw D., 1989. Incidence and clinicopathologic features of meningioma. J. Neurosurg. 71, 665-672.
17. Saloner, D., Uzelac, A., Hetts, S., Martin, A., Dillon, W., 2010. Modern meningioma imaging techniques. J. Neurooncology. 99, 333-340.
18. Simpson, D., 1957. The recurrence of intracranial meningiomas aftersurgical treatment. J. Neurol. Neurosurg. Psychiatr. 20, 22-39.
19. Torres, L.F., Madalazzo, L.E., Werner, B., 1996. Meningiomas, epidemiological and anatomopathological study of 340 cases. Arq. Neurop- siquiatr. 54, 549-556.
20. Tuna, M., Göçer, A.I., Gezercan, Y., Vural, A., Ildan, F., Haciyakupoglu, S., Karadayi, A., 1999. Huge meningiomas: A Review of 93 Cases. Skull Base Surg. 9, 227-238.
21. Yılmaz, I., Gunaldı, O., Eseoglu, M., 2012. Intracranial meningiomas: Investigation of 85 cases with literature search. Türk Nöroşirurji Dergisi 22, 80-83.
22. Wolfsberger, S., Doostkam, S., Boecher-Schwarz, H.G., Roessler, K., VanTrotsenburg, M., Hainfellner, J.A., 2004. Progesterone-receptor index in meningiomas: Correlation with clinico-pathological parameters and review of the literature. Neurosurg. Rev. 27, 238-245.