Eosinophilic granuloma causing pathological fracture of the clavicle: A pediatric case report

Abstract

Langerhans cell histiocytosis is a disease which has different localization and systemic types. Eosinophilic granuloma is a benign form with isolated bone involvement. Patients are generally aged below 10 years (range 5-20 years) and major complaint is progressive pain. Rarely, patients may present with a pathological fracture. The area of involvement is generally long flat bones. The prognosis is good and it may recover spontaneously. Treatment and monitoring of the patient remains controversial. The treatment choices are radiotherapy, chemotherapy and steroid injection with curettage and grafting. The case presented here is about a pediatric patient with a rarely seen pathological fracture of the clavicle and was treated with curettage and grafting.

Keywords

• Child
• Clavicle
• Eosinophilic granuloma
• Pathological fracture

References

1. Albright, A.L., Pollack, I.F., Adelson, P.D., 1999. Principles and practice of pediatric neurosurgery. Thieme, New York-Stuttgart. 453.
2. Alexiou, G.A., Mpairamidis, E., Sfakianos, G., Prodromou, N., 2009. Cranial unifocal langerhans cell histiocytosis in children. J. Pediatr. Surg. 44, 571-574.
3. Basmacı, M., Hastürk, A.S., 2011. Eozinofilik granüloma: Radyolojik ve klinik değerlendirme. Türk Nöroşirürji Dergisi. 21, 262-264.
4. Smith, J., Yuppa, F., Watson, R.C., 1988. Primary tumors and tumor-like lesion of the clavicle. Skeletal Radiol. 17, 235.
5. Tural, S., Karasu, A., Ofluoğlu, O., Bayındır, Ç., Toplamaoğlu, H., 2004. Oksipital kemikte eozinofilik granülom: Olgu sunumu. Düşünen adam. 17, 59-61.
6. Verbist, B., Geusens, E., Brys, P., Verslegers, I., Samson, I., Sciot, R., Baert, A.L., 1998. Langerhans cell histiocytosis of the clavicle: A case report. Eur. Radiol. 8, 1357-1358. Çıraklı et al.