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Year 2013, , 389 - 393, 05.02.2014
https://doi.org/10.5835/jecm.omu.30.05.025

Abstract

References

  • Ahmed, A., Stephens, J.C., Kaus, C.A., Fay, W.P., 2008. Impact of preemptive warfarin dose reduction on anticoagulation after initiation of trimethoprim-sulfamethoxazole or levofloxacin. J. Thromb. Thrombolysis. 26, 44-48.
  • Ansell, J., Hirsh, J., Dalen, J., Bussey, H., Anderson, D., Poller, L., Jacobson, A., Deykin, D., Matchar, D., 2001. Managing oral anticoagulant therapy. Chest. 119, 22-38.
  • Fihn, S.D., Callahan, C.M., Martin, D.C., McDonell, M.B., Henikoff, J.G., White, R.H.,1996.The risk for and severity of bleeding complications in elderly patients treated with warfarin. The National Consortium of Anticoagulation Clinics. Ann Intern Med. 124, 970-979.
  • Hirsh, J., Fuster, V., Ansell, J., Halperin, J.L., 2003. American Heart Association/American College of Cardiology Foundation Guide to Warfarin Therapy. Circulation. 107, 1692-1711.
  • Hirsh, J., Guyatt, G., Albers, G.W., Harrington, R., Schünemann, H.J., 2008. Antithrombotic and thrombolytic therapy: ACCP guidelines; Executive summary: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 133, 71-109.
  • Landefeld, C.S., Goldman, L., 1989. Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy. Am. J. Med. 87, 144-152.
  • Levine, M.N., Raskob, G., Landefeld, S., Hırs J., 1995. Hemorrhagic complications of anticoagulant treatment. Chest. 108, 276-290.
  • Marie, I., Bodack, O.D., 2007. A warfarin-induced subconjunctival hemorrhage. Optometry. 78, 113-118.
  • Marzolini, M., Wynne, H., 2002.Should patients manage their own oral anticoagulation therapy? Rev. Clin. Gerontol. 12, 275-281.
  • Schurgers, L.J., Aebert, H., Vermeer, C., Bültmann, B., Janzen, J., 2004. Oral anticoagulant treatment: Friend or foe in cardiovascular disease? Blood. 104, 3231-3232.
  • Superstein, R., Gomolin, J.E., Hammouda, W., Rosenberg, A., Overbury, O., Arsenault, C., 2000. Prevalence of ocular hemorrhage in patients receiving warfarin therapy. Can. J. Ophthalmol. 35, 385-389.
  • Wiedermann, C.J., Stockner, I., 2008. Warfarin-induced bleeding complications-clinical presentation and therapeutic options. Thromb. Res. 2, 13-18.

Ocular hemorrhage due to warfarin: Five case reports

Year 2013, , 389 - 393, 05.02.2014
https://doi.org/10.5835/jecm.omu.30.05.025

Abstract

An increase in the number of patients treated with anticoagulants has given rise to complications. In present study, five cases with ocular hemorrhages treated with warfarin were presented. Three men and two women applying to emergency between September 2008 and January 2012 were presented. Of cases, one was 55, and others were 65 and over. International normalized ratio (INR) values were, in turn, as follows: 5.40 in case 1, 8.33 in case 2, no coagulation in cases 3 and 4, and 5.30 in case 5. TDP was used in four cases, but merely warfarin treatment was discontinued in one case. No complication developed, and all cases were discharged as INR returned to therapeutic levels. Patients absorbing warfarin may apply to the emergency with atypical hemorrhages, one of which is ocular type. Patients known to be treated with anticoagulants should be evaluated in detail as to clear or unclear hemorrhages. 

References

  • Ahmed, A., Stephens, J.C., Kaus, C.A., Fay, W.P., 2008. Impact of preemptive warfarin dose reduction on anticoagulation after initiation of trimethoprim-sulfamethoxazole or levofloxacin. J. Thromb. Thrombolysis. 26, 44-48.
  • Ansell, J., Hirsh, J., Dalen, J., Bussey, H., Anderson, D., Poller, L., Jacobson, A., Deykin, D., Matchar, D., 2001. Managing oral anticoagulant therapy. Chest. 119, 22-38.
  • Fihn, S.D., Callahan, C.M., Martin, D.C., McDonell, M.B., Henikoff, J.G., White, R.H.,1996.The risk for and severity of bleeding complications in elderly patients treated with warfarin. The National Consortium of Anticoagulation Clinics. Ann Intern Med. 124, 970-979.
  • Hirsh, J., Fuster, V., Ansell, J., Halperin, J.L., 2003. American Heart Association/American College of Cardiology Foundation Guide to Warfarin Therapy. Circulation. 107, 1692-1711.
  • Hirsh, J., Guyatt, G., Albers, G.W., Harrington, R., Schünemann, H.J., 2008. Antithrombotic and thrombolytic therapy: ACCP guidelines; Executive summary: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 133, 71-109.
  • Landefeld, C.S., Goldman, L., 1989. Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy. Am. J. Med. 87, 144-152.
  • Levine, M.N., Raskob, G., Landefeld, S., Hırs J., 1995. Hemorrhagic complications of anticoagulant treatment. Chest. 108, 276-290.
  • Marie, I., Bodack, O.D., 2007. A warfarin-induced subconjunctival hemorrhage. Optometry. 78, 113-118.
  • Marzolini, M., Wynne, H., 2002.Should patients manage their own oral anticoagulation therapy? Rev. Clin. Gerontol. 12, 275-281.
  • Schurgers, L.J., Aebert, H., Vermeer, C., Bültmann, B., Janzen, J., 2004. Oral anticoagulant treatment: Friend or foe in cardiovascular disease? Blood. 104, 3231-3232.
  • Superstein, R., Gomolin, J.E., Hammouda, W., Rosenberg, A., Overbury, O., Arsenault, C., 2000. Prevalence of ocular hemorrhage in patients receiving warfarin therapy. Can. J. Ophthalmol. 35, 385-389.
  • Wiedermann, C.J., Stockner, I., 2008. Warfarin-induced bleeding complications-clinical presentation and therapeutic options. Thromb. Res. 2, 13-18.
There are 12 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Internal Medical Sciences
Authors

Sedat Koçak

Esma Erdemir This is me

Birsen Ertekin

Başar Cander

Cesareddin Dikmetaş This is me

Publication Date February 5, 2014
Submission Date September 10, 2013
Published in Issue Year 2013

Cite

APA Koçak, S., Erdemir, E., Ertekin, B., Cander, B., et al. (2014). Ocular hemorrhage due to warfarin: Five case reports. Journal of Experimental and Clinical Medicine, 30(4), 389-393. https://doi.org/10.5835/jecm.omu.30.05.025
AMA Koçak S, Erdemir E, Ertekin B, Cander B, Dikmetaş C. Ocular hemorrhage due to warfarin: Five case reports. J. Exp. Clin. Med. February 2014;30(4):389-393. doi:10.5835/jecm.omu.30.05.025
Chicago Koçak, Sedat, Esma Erdemir, Birsen Ertekin, Başar Cander, and Cesareddin Dikmetaş. “Ocular Hemorrhage Due to Warfarin: Five Case Reports”. Journal of Experimental and Clinical Medicine 30, no. 4 (February 2014): 389-93. https://doi.org/10.5835/jecm.omu.30.05.025.
EndNote Koçak S, Erdemir E, Ertekin B, Cander B, Dikmetaş C (February 1, 2014) Ocular hemorrhage due to warfarin: Five case reports. Journal of Experimental and Clinical Medicine 30 4 389–393.
IEEE S. Koçak, E. Erdemir, B. Ertekin, B. Cander, and C. Dikmetaş, “Ocular hemorrhage due to warfarin: Five case reports”, J. Exp. Clin. Med., vol. 30, no. 4, pp. 389–393, 2014, doi: 10.5835/jecm.omu.30.05.025.
ISNAD Koçak, Sedat et al. “Ocular Hemorrhage Due to Warfarin: Five Case Reports”. Journal of Experimental and Clinical Medicine 30/4 (February 2014), 389-393. https://doi.org/10.5835/jecm.omu.30.05.025.
JAMA Koçak S, Erdemir E, Ertekin B, Cander B, Dikmetaş C. Ocular hemorrhage due to warfarin: Five case reports. J. Exp. Clin. Med. 2014;30:389–393.
MLA Koçak, Sedat et al. “Ocular Hemorrhage Due to Warfarin: Five Case Reports”. Journal of Experimental and Clinical Medicine, vol. 30, no. 4, 2014, pp. 389-93, doi:10.5835/jecm.omu.30.05.025.
Vancouver Koçak S, Erdemir E, Ertekin B, Cander B, Dikmetaş C. Ocular hemorrhage due to warfarin: Five case reports. J. Exp. Clin. Med. 2014;30(4):389-93.