Paterson-Kelly syndrome in a patient with celiac disease

Abstract

Paterson-Kelly syndrome is characterized with iron deficiency anemia and esophagial web. Association between Paterson-Kelly and Celiac disease is not well-known. Especially in our country, there is insufficient data about these two diseases. We report a case with a complaint of dysphagia and diagnosed as Paterson-Kelly syndrome with celiac disease. Dysphagia was resolved with bougie dilation, oral iron supplement and gluten free diet. We want to emphasize the importance of screening for celiac disease in patient with dysphagia and iron-deficieny anemia.

Keywords

• Bougie dilation,Celiac disease,Dysphagia,Iron-deficiency anemia

References

1. Ackerman, Z., Eliakim, R., Stalnikowicz, R., Rachmilewitz, D., 1996. Role of small bowel biopsy in the endoscopic evaluation of adults with iron deficiency anemia. Am. J. Gastroenterol. 91, 2099-2102.
2. Ben Gamra, O., Mbarek, C., Mouna, C., Zribi, S., Zainine, R., Hariga, I., El Khedim, A., 2007. Plummer vinson syndrome. Tunis Med. 85, 402-404.
3. Bredenkamp, J.K., Castro, D.J., Mickel, R. A., 1990. Importance of iron repletion in the management of Plummer-Vinson syndrome. Ann. Otol. Rhinol. Laryngol. 99, 51-54.
4. Chisholm, M., Ardran, G.M., Callender, S.T., Wright, R., 1971. A follow-up study of patients with post-cricoid webs. Q. J. Med. 40, 409-420.
5. Corazza, G.R., Valentini, R.A., Andreani, M.L., D’Anchino, M., Leva, M.T., Ginaldi, L., De Feudis, L., Quaglino, D., Gasbarrini, G., 1995. Subclinical coeliac disease is a frequent cause of iron-deficiency anaemia. Scand. J. Gastroenterol. 30, 153-156.
6. Dantas, R.O., 1999. Iron deficiency and dysphagia. Am. J. Gastroenterol. 94, 3072-3073.
7. Dickey, W., McConnell, B., 1999. Celiac disease presenting as the Paterson-Brown Kelly (Plummer-Vinson) syndrome. Am. J. Gastroenterol. 94, 527-529.
8. Hoffman, R.M., Jaffe, P.E., 1995. Plummer-Vinson syndrome. A case report and literature review. Arch. Intern. Med. 155, 2008- 2011.

9. Klifto, E.J., Allen, S.K., Metzman, M., Chase P.J., Kupersmit, M., 1983. Plummer-Vinson syndrome: Report of a case and review of the literature. J. Am. Osteopath. Assoc. 83, 56-59.
10. Malhotra, P., Kochhar, R., Varma, N., Kumari, S., Jain, S., Varma, S., 2000. Paterson-Kelly syndrome and celiac disease a rare combination. Indian J. Gastroenterol 19, 191-192.
11. Novacek, G., 2006. Plummer-Vinson syndrome. Orphanet. J. Rare. Dis. 1, 36.
12. Sinha, S.K., Nain, C.K., Udawat, H.P., Prasad, K K., Das, R., Nagi, B., Singh, K., 2008. Cervical esophageal web and celiac disease. J. Gastroenterol. Hepatol. 23, 1149-1152.
13. Sood, A., Midha, V., Sood, N., Bansal, M., 2005. Paterson Kelly syndrome in celiac disease. J. Assoc. Physicians. India. 53, 991- 992.
14. Sood, A., Midha, V., Sood, N., Malhotra, V., 2003. Adult celiac disease in northern India. Indian J. Gastroenterol. 22, 124-126.