Delayed diagnosis of selective immunoglobulin deficiency: A case report

Veysel Kars; Tahsin Celepkolu; Ahmet Yilmaz; Fatih Esmer; Sevdegul Karadas

Case Report

Delayed diagnosis of selective immunoglobulin deficiency: A case report

Year 2016, Volume: 33 Issue: 3, 175 - 177, 06.01.2017

Veysel Kars Tahsin Celepkolu Ahmet Yilmaz Fatih Esmer Sevdegul Karadas

Abstract

Selective immunoglobulin A deficiency (SIgAD) is the most common of all primary immunodeficiency diseases; however, the pathogenesis has not been fully understood. Although most people with SIgAD are asymptomatic, some may present with recurrent infections; such as respiratory disorders, gastrointestinal tracts disorders, and allergic disorders. Herein, we report a case with SIgAD who presented with the complaints of pruritus, dental caries and chronic sinopulmonary infections.

Keywords

Pruritus , Recurrent infections , Selective immunoglobulin a deficiency , Sinopulmonary infections

References

Buckley, R.H., 1975. Clinical and immunologic features of selective IgA deficiency. Birth Defects Orig. Artic. Ser. 11, 134-142.
Conley, Me., Nortarangelod, E. A., 1999. Diagnostic criteria for primary immuno deficiencies. Clin. Immunol. 93, 190-197.
Cunningham, R.C., 2001. Physiology of IgA and IgA deficiency. J. Clin. Immunol. 21, 303-309.
Edwards, E., Razvi, S., Cunningham-Rundles, C., 2004. IgA deficiency: Clinical correlates and responses to pneumococcal vaccine. Clin. Immunol. 111, 93-97.
Fernandes, K.S., Kokron, C.M., Barros, M.T., Kalil, J., Gallottini, M., 2012. Oral manifestations in patients with hypogammaglobulinemia. Oral Surg., Oral Med., Oral Pathol. and Oral Radiol. 114, 19-24. doi: 10.1016/j.oooo.2012.02.006.
Jacob, C.M., Pastorino, A.C., Fahl, K., Carneiro-Sampaio, M., Monteiro, R.C., 2008. Autoimmunity in IgA deficiency: Revisiting the role of IgA as a silent housekeeper. J. Clin. Immunol. 28, 56-61.
Janzi, M., Kull, I., Sjöberg, R., Wan, J., Melén, E., Bayat, N., Ostblom, E., Pan-Hammarström, Q., Nilsson, P., Hammarström, L., 2009. Selective IgA deficiency in early life: Association to infections and allergic diseases during childhood. Clin. Immunol. 133, 78-85.
Legler, D.W., McGhee, J.R., Lynch, D.P., Mestecky, J.F., Schaefer, M.E., Carson, J., Bradley, E.L., Jr. 1981. Jr. Immunodeficiency disease and dental caries in man. Arch. Oral Biol. 26, 905-910.
Phankingthongkum, S., Visitsunthorn, N., Vichyanond, P., 2002. IgA deficiency: A report of three cases from Thailand. Asian Pac. J. Allergy. Immunol. Sep. 20, 203-207.
Yel, L., 2010.Selective IgA deficiency. J. Clin. Immunol. 30, 10-16.

Year 2016, Volume: 33 Issue: 3, 175 - 177, 06.01.2017

Veysel Kars Tahsin Celepkolu Ahmet Yilmaz Fatih Esmer Sevdegul Karadas

Abstract

References

Buckley, R.H., 1975. Clinical and immunologic features of selective IgA deficiency. Birth Defects Orig. Artic. Ser. 11, 134-142.
Conley, Me., Nortarangelod, E. A., 1999. Diagnostic criteria for primary immuno deficiencies. Clin. Immunol. 93, 190-197.
Cunningham, R.C., 2001. Physiology of IgA and IgA deficiency. J. Clin. Immunol. 21, 303-309.
Edwards, E., Razvi, S., Cunningham-Rundles, C., 2004. IgA deficiency: Clinical correlates and responses to pneumococcal vaccine. Clin. Immunol. 111, 93-97.
Fernandes, K.S., Kokron, C.M., Barros, M.T., Kalil, J., Gallottini, M., 2012. Oral manifestations in patients with hypogammaglobulinemia. Oral Surg., Oral Med., Oral Pathol. and Oral Radiol. 114, 19-24. doi: 10.1016/j.oooo.2012.02.006.
Jacob, C.M., Pastorino, A.C., Fahl, K., Carneiro-Sampaio, M., Monteiro, R.C., 2008. Autoimmunity in IgA deficiency: Revisiting the role of IgA as a silent housekeeper. J. Clin. Immunol. 28, 56-61.
Janzi, M., Kull, I., Sjöberg, R., Wan, J., Melén, E., Bayat, N., Ostblom, E., Pan-Hammarström, Q., Nilsson, P., Hammarström, L., 2009. Selective IgA deficiency in early life: Association to infections and allergic diseases during childhood. Clin. Immunol. 133, 78-85.
Legler, D.W., McGhee, J.R., Lynch, D.P., Mestecky, J.F., Schaefer, M.E., Carson, J., Bradley, E.L., Jr. 1981. Jr. Immunodeficiency disease and dental caries in man. Arch. Oral Biol. 26, 905-910.
Phankingthongkum, S., Visitsunthorn, N., Vichyanond, P., 2002. IgA deficiency: A report of three cases from Thailand. Asian Pac. J. Allergy. Immunol. Sep. 20, 203-207.
Yel, L., 2010.Selective IgA deficiency. J. Clin. Immunol. 30, 10-16.

There are 10 citations in total.

Details

Journal Section	Case Report
Authors	Veysel Kars This is me Tahsin Celepkolu This is me Ahmet Yilmaz This is me Fatih Esmer This is me Sevdegul Karadas This is me
Submission Date	January 4, 2017
Acceptance Date	April 3, 2016
Publication Date	January 6, 2017
Published in Issue	Year 2016 Volume: 33 Issue: 3

Cite

APA	Kars, V., Celepkolu, T., Yilmaz, A., … Esmer, F. (2017). Delayed diagnosis of selective immunoglobulin deficiency: A case report. Deneysel Ve Klinik Tıp Dergisi, 33(3), 175-177.
AMA	Kars V, Celepkolu T, Yilmaz A, Esmer F, Karadas S. Delayed diagnosis of selective immunoglobulin deficiency: A case report. J. Exp. Clin. Med. January 2017;33(3):175-177.
Chicago	Kars, Veysel, Tahsin Celepkolu, Ahmet Yilmaz, Fatih Esmer, and Sevdegul Karadas. “Delayed Diagnosis of Selective Immunoglobulin Deficiency: A Case Report”. Deneysel Ve Klinik Tıp Dergisi 33, no. 3 (January 2017): 175-77.
EndNote	Kars V, Celepkolu T, Yilmaz A, Esmer F, Karadas S (January 1, 2017) Delayed diagnosis of selective immunoglobulin deficiency: A case report. Deneysel ve Klinik Tıp Dergisi 33 3 175–177.
IEEE	V. Kars, T. Celepkolu, A. Yilmaz, F. Esmer, and S. Karadas, “Delayed diagnosis of selective immunoglobulin deficiency: A case report”, J. Exp. Clin. Med., vol. 33, no. 3, pp. 175–177, 2017.
ISNAD	Kars, Veysel et al. “Delayed Diagnosis of Selective Immunoglobulin Deficiency: A Case Report”. Deneysel ve Klinik Tıp Dergisi 33/3 (January2017), 175-177.
JAMA	Kars V, Celepkolu T, Yilmaz A, Esmer F, Karadas S. Delayed diagnosis of selective immunoglobulin deficiency: A case report. J. Exp. Clin. Med. 2017;33:175–177.
MLA	Kars, Veysel et al. “Delayed Diagnosis of Selective Immunoglobulin Deficiency: A Case Report”. Deneysel Ve Klinik Tıp Dergisi, vol. 33, no. 3, 2017, pp. 175-7.
Vancouver	Kars V, Celepkolu T, Yilmaz A, Esmer F, Karadas S. Delayed diagnosis of selective immunoglobulin deficiency: A case report. J. Exp. Clin. Med. 2017;33(3):175-7.