A Rare Case: Covid-19 Infection Diagnosed by Transthoracic Fine Needle Aspiration Biopsy

Abstract

Covid 19 is an acute respiratory disease caused by a novel type of Coronavirus (SARS-CoV-2) that was first detected in Wuhan, Hubei Province of China. Its most common symptoms are fever, cough, and weakness; and in the early stages, there may not be findings on chest computed tomography. In pulmonary involvement, peripheral ground-glass areas, a cobblestone appearance, consolidated areas, and interlobular septal thickening, which are usually prominent in the lower lobes may be seen in thorax computed tomography. Consolidation, solid nodules, halo sign, inverted halo sign, vascular enlargement, subpleural line, air bronchograms, and bronchiectasis are other less common findings. In our case, we aimed to present our 69 years old female patient with bilateral nodular densities on thoracic CT and transthoracic fine-needle aspiration biopsy result was reported as lesions compatible with interstitial fibrosis due to Covid-19 inflammation.

Keywords

• covid- 19
• nodule
• Transthoracic Fine Needle Aspiration Biopsy

References

1. 1- Wong HYF, Lam HYS, Fong AH, et al. Frequency and Distribution of Chest Radiographic Findings in COVID-19 Positive Patients. Radiology 2020:201160.
2. 2- Pekcevik Y, Belet U. Patient Management in the Radiology Department, the Role of Chest Imaging During the SARS-CoV-2 Pandemic and Chest CT Findings Related to COVID-19 Pneumonia. The journal of Tepecik Education and Research Hospital. 2020;30(2): 195-212.
3. 3- Çinkooğlu A, Hepdurgun C, Bayraktaroğlu S, Ceylan N, Savaş R. CT imaging features of COVID-19 pneumonia: initial experience from Turkey Diagn Interv Radiol. 2020;26(4):308-314.
4. 4- Xie X, Zhong Z, Zhao W, Zheng C, Wang F, Liu J. Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT-PCR testing. 2020;296(2):41-45.
5. 5- Huang P, Liu T, Huang L, et al. Use of Chest CT in Combination with Negative RT-PCR Assay for the 2019 Novel Coronavirus but High Clinical Suspicion. Radiology. 2020;295(1):22–23.
6. 6- Fang Y, Zhang H, Xie J et al. Sensitivity of chest CT for COVID-19: comparison to RT-PCR. 2020;296(2):E115-E117.
7. 7- World Health Organization. Director-General's remarks at the media briefing on 2019-nCoV on 11 February 2020.
8. 8- Wang D, Hu B, Hu C, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA 2020;323:1061–9.

9. 9- Chung M, Bernheim A, Mei X, et al. CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV) Radiology. 2020;295(1):202–207.
10. 10- Fang Y, Zhang H, Xu Y, Xie J, Pang P, Ji W. CT Manifestations of Two Cases of 2019 Novel Coronavirus (2019-nCoV) Pneumonia. Radiology. 2020;295(1):208–209.
11. 11- Zheng Y., Yun Z., Yi W. et al. Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review. European Radiology 2020;30(8):4381-4389.
12. 12- Pan Y,, Guan H,, Zhou S. et al. Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China. Eur Radiol.2020;30(6):3306-3309.
13. 13- Ai T, Yang Z, Hou H et al. Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases. 2020; 296(2):E32-E40.
14. 14- Zhang H, Zhou P, Wei Y, et al. Histopathologic changes and SARS-CoV-2 Immunostaining in the lung of a patient with COVID-19. Ann Intern Med. 2020;172:629–632.
15. 15- Pernazza A, Mancini M, Rullo E, et al. Early histologic findings of pulmonary SARS-CoV-2 infection detected in a surgical specimen. Virchows Arch. 2020;477(5):743-748. doi: 10.1007/s00428-020-02829-1.
16. 16- Raad N, Ghorbani J, Mikaniki N, Haseli S, Karimi-Galougahi M. Otitis media in coronavirus disease 2019: a case series. J Laryngol Otol. 2021;7:1–4.