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Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels

Year 1991, Volume: 8 Issue: 4, 343 - 348, 22.12.2009

Abstract

Experiments were carried out on 140 Swiss-Albino rats. Ten rats were appplied stress and this group was called stress group and the other ten rats were chosen as the control group. Cimetidine were given to 60 rats and physiological salina to the other 60 rats.
The average serum creatinin levels was found to be 0.4710.04 mg/dl, in the nonstressgroup and 0.40+0.04 mg/dl in the stress group. The mean level of boold urea nitrogen (BUN) was found to be 5.0+0.4 mg/dl'in the group that was not applied stress and 4.9±0.5 mg/dl'in the stress group. It was found stress was not veiy efeective on serum creatinine and BUN levels (p>0.05).
The differences on serum creatine and BUN levels between control and experimental group, 1,2,3,7,14 and 21 days after cimetidine therapy, were insignificant (p>0.05).
In according to our results; stress and cimetidine therapy were not effective on the average serum levels of creatinine and BUN.

Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels

Year 1991, Volume: 8 Issue: 4, 343 - 348, 22.12.2009

Abstract

Deneyler 140 erkek sıçan üzerinde yapıldı. 10 sıçana stres uygulandı. 10 sıçan kontrol grubu olarak alındı, 60 sıçana stresden sonra simetidin, diğer 60 sıçana da serum fizyolojik verildi. Stres uygulanmayan grupta ortalama serum kreatinin düzeyleri 0.47+0.04mg/dl, stresli grupta 0.4010.04mg/dl olarak bulundu. Kan üre azotu (BUN) düzeyleri stressiz grupta ortalama 5,0±0,4mg/dl, stresli grupta 4,9+0.5mg/dl idi. Stresin serum kreatinin ve BUN düzeylerine önemli bir etkisi olmadığı gözlendi (p>0.05). Simetidin tedavisinin 1,2,3,7,14 ve 21. günleri serum kreatinin ve BUN düzeyleri kontrol grubuna göre istatistiki yönden önemli değildi (P>0.05). Sonuçlarımız stres ve simetidin tedavisinin serum kreatinin ve BUN seviyelerine etkisi olmadığını gösterdi. Anahtar Kelimeler: 

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Details

Primary Language English
Subjects Health Care Administration
Journal Section Basic Medical Sciences
Authors

Y. Kesim This is me

M. Alvur This is me

Y. Alvur This is me

S. Çelik This is me

Publication Date December 22, 2009
Submission Date November 19, 2009
Published in Issue Year 1991 Volume: 8 Issue: 4

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APA Kesim, Y., Alvur, M., Alvur, Y., Çelik, S. (2009). Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. Journal of Experimental and Clinical Medicine, 8(4), 343-348.
AMA Kesim Y, Alvur M, Alvur Y, Çelik S. Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. J. Exp. Clin. Med. December 2009;8(4):343-348.
Chicago Kesim, Y., M. Alvur, Y. Alvur, and S. Çelik. “Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels”. Journal of Experimental and Clinical Medicine 8, no. 4 (December 2009): 343-48.
EndNote Kesim Y, Alvur M, Alvur Y, Çelik S (December 1, 2009) Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. Journal of Experimental and Clinical Medicine 8 4 343–348.
IEEE Y. Kesim, M. Alvur, Y. Alvur, and S. Çelik, “Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels”, J. Exp. Clin. Med., vol. 8, no. 4, pp. 343–348, 2009.
ISNAD Kesim, Y. et al. “Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels”. Journal of Experimental and Clinical Medicine 8/4 (December 2009), 343-348.
JAMA Kesim Y, Alvur M, Alvur Y, Çelik S. Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. J. Exp. Clin. Med. 2009;8:343–348.
MLA Kesim, Y. et al. “Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels”. Journal of Experimental and Clinical Medicine, vol. 8, no. 4, 2009, pp. 343-8.
Vancouver Kesim Y, Alvur M, Alvur Y, Çelik S. Effect Of Stress And Cimetidine Therapy On Serum Creatinine And Blood Urea Nitrogen Levels. J. Exp. Clin. Med. 2009;8(4):343-8.