Abstract
Analysis of The Cases With Henoch-Schönlein Vasculitis
Henoch-Schönlein vasculitis is the most common systemic vasculitis in children and it has a benign course and characterized purpura, arthritis and gastrointestinal and/or renal involvement. In this study we planned to analyze and compare of the clinical and laboratory characteristics of the patient with Henoch-Schönlein vasculitis with literature. We analyzed 135 cases with Henoch-Schönlein vasculitis, who.had been followed up at the departments of pediatrics of Ondokuz Mayıs University and Gülhane Military Medical School between January 1993 and January 2000. retrospectively.
Of the 135 patients, eighty (59.2%) were male and fifty-five (40.8%) were girl, and the median age was 9.5 years (10 months to 17 years). The distribution of the patients to Die season was as follows: 15% in spring. 18.5% in summer, 21.1% in autumn, and 45.4% in winter. The most complaints of admission were purpura (100%). abdominal pain (62%) and arthralgia (48.8%). There was a positive history of upper respiratory tract infection in the last month in 4.1.4% of the cases. On physical examination, purpura, arthritis, edema of the legs, fever and hypertension were, found in the 100%. 37.7%, 3-1.8%, 1 1%) and 5.9% of the cases, respectively. Gastrointestinal hemorrhage, renal involvement, and scrotal involvement were observed 29.6%, 55.5% and 7,4% of the cases, respectively. II was learned that one patient had been appendect.om.teed a month before. While the improvement lime has not been different between the cases with or without complication, microscopic hematuria continued 2 to 6 months in the patients who had renal involvement.
Henoch-Schönlein purpura has a benign course and permanent complications resulted
from organ involvement are very rare.
Henoch-Schönlein vasküliti, çocuklarda en sık görülen sistemik vaskülit olup purpura. arlriL ve gastrointestinal ve/veya böbrek tutulumu ile karakterize selim seyirli bir hastalıktır. Bu çalışmada Henoch-Schönlein vasküliti tanısı alan hastalarımızın klinik ve laboratuar bulgularını inceleyerek literatür bilgisi ile karşılaştırılması planlandı. Bu calı-nıada Ocak 1993 ile Ocak 2000 tarihleri arasında Ondokuz Mayıs Üniversitesi ve Gülhane Askeri Tıp Akademisi Pediatri Anabilim Dallarında Henoch-Schönlein vasküliti tanısı almış 135 hasta retrospektif olarak gözden geçirildi.
Hastaların 80'i (%59.2) erkek. 55'i (%40.8) kız olup, medyan yaş 9.5 idi (10 ay - 17 yaş arası). Olguların mevsimlere göre dağılımı: İlkbahar %15, yaz %18.5. sonbahar %2 1.1 ve %45.4 kış. En sık başvuru şikayetleri döküntü (%100), karın ağrısı (%62) ve eklem ağrısı (%48.8) idi. Fizik muayenede purpura, artrit, ayaklarda ödem, ateş ve hipertansiyon sırasıyla %100, %37.7, %31.8, %1 1 ve %5.9 oranında bulundu. Hastaların seyrinde gastrointestinal kanama, renal tutulum ve skrotal tutulum sırasıyla %29.6, %55.5 ve %7.4 oranlarında saptandı. Bir hastanın bir ay önce apendektomi geçirdiği öğrenildi. Organ tutulumu olan ve olmayan hastalarda iyileşme zamanı farklılık göstermezken, renal tutulumu olan hastalarda mikroskobik hematini 2 ile 6 ay devam etli.
Henoch-Schönlein vasküliti selim seyiıii bir hastalık olup organ tutulumu sonucu kalıcı komplikasyonlar çok nadirdir.
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| Primary Language | English |
|---|---|
| Journal Section | Basic Medical Sciences |
| Authors | |
| Publication Date | December 23, 2009 |
| Submission Date | November 12, 2009 |
| Published in Issue | Year 2001 Volume: 18 Issue: 4 |
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