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Assessment of sexual dysfunction in women with Behcet’s disease

Year 2012, Volume: 29 Issue: 1, 28 - 32, 17.04.2012

Abstract

Behcet’s disease (BD) is a progressive inflammatory disease which urogenital involvement mainly consists of genital aphthous ulcers, urethritis and recurrent cystitis. We evaluated female sexual dysfunction (FSD) in women with BD and investigate whether coexistent depression has an effect on sexual functions. A total of 25 women with BD and 25 age voluntary healthy women who served as the control group were evaluated with a detailed medical and sexual history, including female sexual function index (FSFI) ques¬tionnaire and the Beck Depression Inventory (BDI). Serum steroid hormone levels were measured in all subjects. The group with BD had higher scores for BDI than the control patients (p<0.001) and the mean FSFI score was significantly lower than the score for the controls. FSD was diagnosed in 14 of 25 BD patients (56%), while 4 of 25 healthy women (16%). Women with BD scored worse on all domains of FSD than did the controls (p<0.001). In the correlation analysis, the FSFI score indicated a significant negative correlation with the BDI score (r=-0.901, p<0.001).The results of our study have shown that female patients with BD have distinct sexual dysfunction compared with healthy controls and coexistent depression has an additional negative effect on sexual function.

J. Exp. Clin. Med., 2012; 29:28-32

References

  • Aksu, K., Keser, G., Gunaydın, G., Ozbek, S.S., Colakoğlu, Z., Gümüşdiş, G., 2000. Erectile dysfunction in Behcet’s disease without neurologi- cal involvement: Two case reports. Rheumatol. 39, 1429-1431.
  • Anastasiadis, A.G., Davis, A.R., Ghafar, M.A., Burchardt, M., Shabsigh. R., 2002. The epidemiology and definition of female sexual disorders. World J. Urol. 20, 74-78.
  • Aydın, G., Basar, M.M., Keles, I., Ergün, G., Orkun, S., Batislam, E., 2006. Relationship between sexual dysfunction and psychiatric status in premenopausal women with fibromyalgia. Urology. 67, 156-161.
  • Beck, A.T., Epstein, N., Brown, G., Steer, R.A., 1988. An inventory for measuring clinical anxiety: Psychometric properties. J. Consult. Clin. Psychol. 56, 893-897.
  • Behçet, H., 1937. Über residivierende, aphtöse, durch ein Virus verursachte Gecchwüre am Mund, am Auge und an den Genitalien. Dermatol. Wochenschr. 105, 1152-1157.
  • Bonierbale, M., Lancon, C., Tignol, J., 2003. The ELIXIR study: Evaluation of sexual dysfunction in 4557 depressed patients in France. Curr. Med. Res. Opin.19, 114-124.
  • Calikoglu, E., Onder, M., Cosar, B., Candansayar, S., 2001. Depression, anxiety levels and general psychological profile in Behcet’s disease. Dermatol. 203, 238-240.
  • Cetinel, B., Akpinar, I., Uygun, N., Solok, V., Yazici, H., 1999. Bladder involvement in Behçet’s syndrome. J. Urol. 161, 52-56.
  • Erdoğru, T., Koçak, T., Serdaroğlu, P., Kadioğlu, A., Tellaloğlu, S., 1999. Evaluation and therapeutic approaches of voiding and erectile dysfunc- tion in neurological Behçet’s syndrome. J. Urol. 162, 147-153.
  • Fisher, W.A., Boroditsky, R., Bridges, M., 1999. Canadian contraception study 1998. Can. J. Hum. Sex. 8, 161-165.
  • Goldmeier, D., Judd, A., Schroeder, K., 2000. Prevalence of sexual dysfunction in new heterosexual attenders at a central London genitourinary medicine clinic in 1998. Sex Transm. Infect. 76, 208-210.
  • International Study Group for Behcet’s Disease. 1990. Criteria for the diagnosis of Behcet’s disease. Lancet. 335, 1078-1080.
  • Kadıoglu, P., Yalın, S.A., Tiryakioglu, O., Gazioglu, N., Oral, G., Sanli, O., 2005. Sexual dysfunction in women with hyperprolactinemia: A pilot study report. J. Urol. 174, 1921-1925.
  • Kocak, M., Basar, M.M., Vahapoglu, G., Mert, H.C., Güngör, S., 2009. The effect of behcet’s disease on sexual function and psychiatric status of premenopausal women. J. Sex. Med. 6, 1341-1348.
  • Laumann, E., Paik, A., Rosen, R., 1999. Sexual dysfunction in the United States: Prevalence and predictors. J.A.M.A. 281, 537-544.
  • Monastero, R., Camarda, C., Pipia, C., Lopez, G., Camarda, L.K., Baiamonte, V., 2004. Cognitive impairment in Behcet’s disease patients with- out overt neurological involvement. J. Neurol. Sci. 220, 99-104.
  • Oksuz, E., Malhan, S., 2006. Prevalence and risk factors for female sexual dysfunction in Turkish women. J. Urol. 175, 654-658.
  • Rosen, R.C., 2002. Assessment of female sexual dysfunction: Review of validated methods. Fertil. Steril. Suppl. 77, 89.
  • Saito, M., Miyagawa, I., 2000. Bladder dysfunction due to Behçet’s disease. Urol. Int. 65, 40-42.
  • Taner, E., Cosar, B., Burhanoğlu, S., Calikoğlu, E., Onder, M., Arikan, Z., 2007. Depression and anxiety in patients with Behcet’s disease com- pared with that in patients with psoriasis. Int. J. Dermatol. 46, 1118-1124.
  • Theodorou, C., Floratos, D., Hatzinicolaou, P., Vaiopoulos, G., 1999. Neurogenic bladder dysfunction due to Behçet’s disease. Int. J. Urol. 6, 423-425.
  • Tikiz, C., Muezzinoglu, T., Pirildar, T., Taskın, E.O., Fırat, A., Tuzun, C., 2005. Sexual dysfunction in female subjects with fibromyalgia. J. Urol. 174, 620-623.
Year 2012, Volume: 29 Issue: 1, 28 - 32, 17.04.2012

Abstract

References

  • Aksu, K., Keser, G., Gunaydın, G., Ozbek, S.S., Colakoğlu, Z., Gümüşdiş, G., 2000. Erectile dysfunction in Behcet’s disease without neurologi- cal involvement: Two case reports. Rheumatol. 39, 1429-1431.
  • Anastasiadis, A.G., Davis, A.R., Ghafar, M.A., Burchardt, M., Shabsigh. R., 2002. The epidemiology and definition of female sexual disorders. World J. Urol. 20, 74-78.
  • Aydın, G., Basar, M.M., Keles, I., Ergün, G., Orkun, S., Batislam, E., 2006. Relationship between sexual dysfunction and psychiatric status in premenopausal women with fibromyalgia. Urology. 67, 156-161.
  • Beck, A.T., Epstein, N., Brown, G., Steer, R.A., 1988. An inventory for measuring clinical anxiety: Psychometric properties. J. Consult. Clin. Psychol. 56, 893-897.
  • Behçet, H., 1937. Über residivierende, aphtöse, durch ein Virus verursachte Gecchwüre am Mund, am Auge und an den Genitalien. Dermatol. Wochenschr. 105, 1152-1157.
  • Bonierbale, M., Lancon, C., Tignol, J., 2003. The ELIXIR study: Evaluation of sexual dysfunction in 4557 depressed patients in France. Curr. Med. Res. Opin.19, 114-124.
  • Calikoglu, E., Onder, M., Cosar, B., Candansayar, S., 2001. Depression, anxiety levels and general psychological profile in Behcet’s disease. Dermatol. 203, 238-240.
  • Cetinel, B., Akpinar, I., Uygun, N., Solok, V., Yazici, H., 1999. Bladder involvement in Behçet’s syndrome. J. Urol. 161, 52-56.
  • Erdoğru, T., Koçak, T., Serdaroğlu, P., Kadioğlu, A., Tellaloğlu, S., 1999. Evaluation and therapeutic approaches of voiding and erectile dysfunc- tion in neurological Behçet’s syndrome. J. Urol. 162, 147-153.
  • Fisher, W.A., Boroditsky, R., Bridges, M., 1999. Canadian contraception study 1998. Can. J. Hum. Sex. 8, 161-165.
  • Goldmeier, D., Judd, A., Schroeder, K., 2000. Prevalence of sexual dysfunction in new heterosexual attenders at a central London genitourinary medicine clinic in 1998. Sex Transm. Infect. 76, 208-210.
  • International Study Group for Behcet’s Disease. 1990. Criteria for the diagnosis of Behcet’s disease. Lancet. 335, 1078-1080.
  • Kadıoglu, P., Yalın, S.A., Tiryakioglu, O., Gazioglu, N., Oral, G., Sanli, O., 2005. Sexual dysfunction in women with hyperprolactinemia: A pilot study report. J. Urol. 174, 1921-1925.
  • Kocak, M., Basar, M.M., Vahapoglu, G., Mert, H.C., Güngör, S., 2009. The effect of behcet’s disease on sexual function and psychiatric status of premenopausal women. J. Sex. Med. 6, 1341-1348.
  • Laumann, E., Paik, A., Rosen, R., 1999. Sexual dysfunction in the United States: Prevalence and predictors. J.A.M.A. 281, 537-544.
  • Monastero, R., Camarda, C., Pipia, C., Lopez, G., Camarda, L.K., Baiamonte, V., 2004. Cognitive impairment in Behcet’s disease patients with- out overt neurological involvement. J. Neurol. Sci. 220, 99-104.
  • Oksuz, E., Malhan, S., 2006. Prevalence and risk factors for female sexual dysfunction in Turkish women. J. Urol. 175, 654-658.
  • Rosen, R.C., 2002. Assessment of female sexual dysfunction: Review of validated methods. Fertil. Steril. Suppl. 77, 89.
  • Saito, M., Miyagawa, I., 2000. Bladder dysfunction due to Behçet’s disease. Urol. Int. 65, 40-42.
  • Taner, E., Cosar, B., Burhanoğlu, S., Calikoğlu, E., Onder, M., Arikan, Z., 2007. Depression and anxiety in patients with Behcet’s disease com- pared with that in patients with psoriasis. Int. J. Dermatol. 46, 1118-1124.
  • Theodorou, C., Floratos, D., Hatzinicolaou, P., Vaiopoulos, G., 1999. Neurogenic bladder dysfunction due to Behçet’s disease. Int. J. Urol. 6, 423-425.
  • Tikiz, C., Muezzinoglu, T., Pirildar, T., Taskın, E.O., Fırat, A., Tuzun, C., 2005. Sexual dysfunction in female subjects with fibromyalgia. J. Urol. 174, 620-623.
There are 22 citations in total.

Details

Primary Language English
Journal Section Surgery Medical Sciences
Authors

Cengiz Kara

Berkan Resorlu This is me

İzzet Çiçekbilek This is me

Ali Ünsal This is me

Publication Date April 17, 2012
Submission Date August 24, 2011
Published in Issue Year 2012 Volume: 29 Issue: 1

Cite

APA Kara, C., Resorlu, B., Çiçekbilek, İ., Ünsal, A. (2012). Assessment of sexual dysfunction in women with Behcet’s disease. Journal of Experimental and Clinical Medicine, 29(1), 28-32. https://doi.org/10.5835/jecm.omu.29.01.008
AMA Kara C, Resorlu B, Çiçekbilek İ, Ünsal A. Assessment of sexual dysfunction in women with Behcet’s disease. J. Exp. Clin. Med. June 2012;29(1):28-32. doi:10.5835/jecm.omu.29.01.008
Chicago Kara, Cengiz, Berkan Resorlu, İzzet Çiçekbilek, and Ali Ünsal. “Assessment of Sexual Dysfunction in Women With Behcet’s Disease”. Journal of Experimental and Clinical Medicine 29, no. 1 (June 2012): 28-32. https://doi.org/10.5835/jecm.omu.29.01.008.
EndNote Kara C, Resorlu B, Çiçekbilek İ, Ünsal A (June 1, 2012) Assessment of sexual dysfunction in women with Behcet’s disease. Journal of Experimental and Clinical Medicine 29 1 28–32.
IEEE C. Kara, B. Resorlu, İ. Çiçekbilek, and A. Ünsal, “Assessment of sexual dysfunction in women with Behcet’s disease”, J. Exp. Clin. Med., vol. 29, no. 1, pp. 28–32, 2012, doi: 10.5835/jecm.omu.29.01.008.
ISNAD Kara, Cengiz et al. “Assessment of Sexual Dysfunction in Women With Behcet’s Disease”. Journal of Experimental and Clinical Medicine 29/1 (June 2012), 28-32. https://doi.org/10.5835/jecm.omu.29.01.008.
JAMA Kara C, Resorlu B, Çiçekbilek İ, Ünsal A. Assessment of sexual dysfunction in women with Behcet’s disease. J. Exp. Clin. Med. 2012;29:28–32.
MLA Kara, Cengiz et al. “Assessment of Sexual Dysfunction in Women With Behcet’s Disease”. Journal of Experimental and Clinical Medicine, vol. 29, no. 1, 2012, pp. 28-32, doi:10.5835/jecm.omu.29.01.008.
Vancouver Kara C, Resorlu B, Çiçekbilek İ, Ünsal A. Assessment of sexual dysfunction in women with Behcet’s disease. J. Exp. Clin. Med. 2012;29(1):28-32.