Hoigne’s syndrome following the injection of repeating benzathine penicillin G: A case report

Year 2018, Volume: 35 Issue: 2, 45 - 47, 25.10.2019

Hayriye Gönüllü , Sevdegül Karadaş Mehmet Coşkun Aykaç Temel Tombul

Abstract

Hoigne’s syndrome is characterized by the development of acute neuropsychi-
atric symptoms which are mainly panic-like anxiety state and conversive neu-
rosis. We here report a 60-year-old man with Hoigne’s syndrome. Emergency
physicians should always keep in mind Hoigne’s syndrome. 

Keywords

Benzathine penicillin , Emergency department , Hoigne’s syndrome

References

• Araszkiewicz, A., Rybakowski, J.K., 1997. Hoigne’s syndrome, kindling, and panic disorder. Depress. Anxiety. 4, 139-143.
• Baran, R., 2014. Proximal nail fold intralesional steroid injection responsible for Hoigné syndrome. J. Eur. Acad. Dermatol. Wochenschr. 89, 1350-1356.
• Landais, A., Marty, N., Bessis, D., Pages, M., Blard, J.M., 2014. Hoigne syndrome following an intravenous injection of ceftriaxone: A case report. Rev. Med. Interne. 35, 199-201.
• Magiera, P., Trojanowski, L., Leszczyński, L., 1994. Acute non-allergic reaction after administration of penicillin as a factor in the occurrence of neurotic symptoms. Psychiatr. Pol. 28, 677-685.
• Rallis, E., Moussatou, V., Saltos, L., 2009. Clarithromycin-induced Hoigne syndrome in a patient treated for rosacea. J. Eur. Acad. Dermatol. Venereol, 23, 1093-1094.
• Rockney, R.A., 1987. Variant of Hoigne’s syndrome following intramuscular cefoxitin sodium? Am. J. Dis. Child. 141, 475-476. Sawa, H., Balcar-Boroń, A., Kucharski, E., Olijewski, S., Slowik, J., 1977,
• Hoigńe syndrome: A non-allergic complication during penicillin administration. Pediatr. Pol. 52, 1285-1287.
• Schmied, C., Schmied, E., Vogel, J., Saurat, J.H., 1990. Hoigné’s syndrome or pseudo-anaphylactic reaction to procaine penicillin G: A still current classic. Schweiz. Med. Wochenschr. 120, 1045-1049.
• Schreiber, W., Krieg, J.C., 2001. Hoigne syndrome. Case report and current literature review. Nervenarzt. 72, 546-548.
• Silber, T.J., D’Angelo, L., 1985. Psychosis and seizures following the injection of penicillin G procaine. Hoigne’s syndrome. Am. J. Dis. Child. 139, 335-337.
• Thompson, T.M., Theobald, J.L., 2016. Hoigne syndrome: A little-known adverse effect of lidocaine. Am. J. Emerg. Med, 34, 679. Zdziarski, P., 2001. Hoigne syndrome as an acute non-allergic reaction to different drugs: Case reports. Pol. Merkur. Lekarski. 10, 453-455.