Research Article
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Year 2019, Volume: 36 Issue: 1, 1 - 8, 04.12.2019

Abstract

References

  • Alp R, Selek Ş, Alp Sİ, Taşkın A, Koçyiğit A., 2010. Oxidative and antioxidative balance in patients of migraine. Eur Rev Med Pharmacol Sci. 14:877-882.
  • Atmaca G., 2004. Antioxidant effects of sulfur-containing amino acids. Yonsei Med J. 45:776–788.
  • Bektas H, Vural G, Gumusyayla S, Deniz O, Alisik M, Erel O., 2016. Dynamic thiol–disulfide homeostasis in acute ischemic stroke patients. Acta Neurol Belg. 116:489–494.
  • Biswas S, Chida AS, Rahman I., 2006. Redox modifications of protein-thiols: emerging roles in cell signaling. BiochemPharmacol. 71:551-64. 23.
  • Blokhina O, Virolainen E, Fagerstedt KV., 2003. Antioxidants, Oxidative Damage and Oxygen Deprivation Stress: a Review. Annals of Botany. 91:179-94.
  • Bockwski L, Sobaniec W, Kulak W, et al., 2008. Serum and intraerythrocyte antioxidant enzymes and lipid peroxides in children with migraine. Pharmacol. 60:542–548.
  • Boran E, Bolay H., 2013. Migren Patofizyolojisi Nöropsikiyatri Arşivi. 50 Özel Sayı 1: 1-7.
  • Cadenas E., 1989. Biochemistry of oxygen toxicıty. Annu Rev Biochem. 58:79–110.
  • Circu ML, Aw TY. 2010. Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med. 48(6): 749–762.
  • Erel O., 2004. A novel automated direct measurement method fortotal antioxidant capacity using a new generation, morestable ABTS radical cation. Clin Biochem. 37:277–285.
  • Erel O, Neselioglu S., 2014. A novel and automated assay for thiol/disulphide homeostasis. ClinBiochem. 47:326-332.
  • Eren Y, Dirik E, Neselioglu S, Erel O., 2015. Oxidative stress and decreased thiol level in patients with migraine: cross-sectional study. Acta Neurol Belg. 115:643–649.
  • Erol I, Alehan F, Aldemir D, Ogus E., 2010. Increased vulnerability to oxidative stress in pediatric migraine patients, Pediatr Neurol. 43:21-24.
  • Ertas M, Baykan B, Orhan EK, Zarifoglu M, Karli N, Saip S et al., 2012. One-year prevalence and the impact of migraine and tension-type headache in Turkey: a nationwide home-based study in adults. J Headache Pain. 13(2):147-57.
  • Gruber HJ, Bernecker C, Lechner A, et al., 2010. Increased nitric oxide stress is associated with migraine. Cephalalgia. 30:486–492.
  • Headache Classification Committee of the International Headache Society., 2013. The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia. 33(9):629-808.
  • Hu ML., 1994. Measurement of protein thiol groups and glutathione in plasma. Methods Enzymol 233:380–385.
  • Jones DP, Liang Y., 2009. Measuring the poise of thiol/disulfide couples in vivo. Free Radic Biol Med. 15;47(10):1329-38.
  • Kayacan Y, Yazar H, Cerit G, Ghojebeigloo BE., 2019. A new oxidative stress indicator: Effect of 5-hydroxy tryptophan on thiol-disülfid homeostasis in exercise. Nutrition. 63-64:114-119.
  • Kayacan Y, Yazar H, Kısa EC, Ghojebeiglo BE., 2018. A novel biomarker explaining the role of oxidative stress in exercise and l-thyrosine supplementation: thiol/disulphide homeostasis. Arch Physiol Biochem. Jul;124(3):232-236.
  • Kundi H, Ates I, Kiziltunc E, Cetin M, Cicekcioglu H, Neselioglu S, et al. 2015. A novel oxidative stress marker in acute myocardial infarction; thiol/disulphide homeostasis. Am J EmergMed. Nov;33(11):1567-71.
  • Kurt ANC, Aydın A, Demir H, Erel O., 2017. Headache in children and dynamic thiol/disulfide balance evaluation with a new method. Neurol Sci. 38(8):1495–1499.
  • Lance JW., 1993. Current concepts of migraine pathogenesis. Neurology. 43:S11–S15
  • Matteucci E, Giampietro O., 2010. Thiol signalling network with an eye to diabetes. Molecules. 15:8890-903.25.
  • Méndez-Armenta M, Nava-Ruíz C, Juárez-Rebollar D, Rodríguez Martínez E, Gómez PY., 2014. Oxidative stress associated with neuronal apoptosis in experimental models of epilepsy. Oxidative med Cell Longev. 293689.
  • Noseda R, Burstein R., 2013. Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, CSD, sensitization and modulation of pain. Pain. 154 Supp 1:S44-53.
  • Oz A, Uguz AC., 2015. Migren patogenezinde oksidatif strese duyarlı TRP kanallarının rolleri. Med J SDU. 22(4):144-150.
  • Pasaoglu H, Sancak B, Bukan N., 2004. Lipid peroxidation and resistance to oxidation in patients with type 2 diabetes mellitus. Tohoku J Exp Med. 203:211–218.
  • Prabhu A, Sarcar B, Kahali S, Yuan Z, Johnson JJ, Adam KP et al., 2014. Cysteine catabolism: a novel metabolic pathway contributing to glioblastoma growth. CancerRes. 4(3): 787–796.
  • Reuter U, Bolay H, Jansen-Olesen I, Chiarugi A, Sanchez del Rio M, Letourneau R, et al., 2001. Delayed inflammation in rat meinges: implications for migraine pathophysiology. Brain. 124:2490-2502.
  • Rodrigues SD, Batista GB, Ingberman M, Pecoits-Filho R, Nakao LS., 2012. Plasma cysteine/cystine reduction potential correlates with plasma creatinine levels in chronic kidney disease. Blood Purif. 34(3–4): 231–237.
  • Sen CK, Packer L., 2000. Thiol homeostasis and supplements in physical exercise. Am J Clin Nutr. 72:653-69.
  • Sharma R, Macy S, Richardson K, Lokhnygina Y, Laskowitz DT., 2014. A blood-based biomarker panel to detect acute stroke. J Stroke Cerebrovasc Dis. 23(5):910–918.
  • Stewart WF, Lipton RB, Celentano DD, Reed ML., 1992. Prevalence of migraine headache in the United States. Relation to age, income, race and other sociodemographic factors. JAMA. 267;(1):64-9.
  • Tetik S, Ahmad S, Alturfan AA, Fresko I, Disbudak M, Sahin Y et al., 2010. Determination of oxidant stress in plasma of rheumatoid arthritis and primary osteoarthritis patients. Indian J Biochem Biophys. 47(6):353–358.
  • Tuncel D, Tolun FI, Gokce M. et al., 2008. Oxidative stress in migraine with and without aura. Biol Trace Elem Res 126:92–97.
  • Uzar E, Evliyaoglu O, Toprak G, Acar A, Yucel Y, Calisir T et al. 2011. Increased asymmetric dimethylarginine and nitric oxide levels in patients with migraine, J Headache Pain. 12:239–243.
  • Valko M, Leibfritz D, Moncola J, Cronin MTD, Mazura M, Telser J., 2007. Free radicals and antioxidants in normal physiological functions and human disease. The International Journal of Biochemistry & Cell Biology. 39(1):44-84.
  • Yılmaz G, Sürer H, Inan LE, Coşkun O, Yücel D., 2007. Increased nitrosative and oxidative stress in platelets of migraine patients. Tohoku J. Exp. Med. 211:23-30.
  • Yılmaz N, Aydın O, Yegin A, Tiltak A, Eren E, Aykal G., 2011. Impaired oxidative balance and association of blood glucose, insulin and HOMA-IR index in migraine. Biochemia Medica. 21(2):145–51.
  • Yılmaz N, Aydın O, Yegin A, Tiltak A, Eren E., 2011. Increased levels of total oxidant status and decreased activity of arylesterase in migraineurs, Clinical Biochemistry. 44;832–837.

Thiol disulfide homeostasis as oxidative stress marker in migraine patients

Year 2019, Volume: 36 Issue: 1, 1 - 8, 04.12.2019

Abstract

Migraine is a very common disease. Annual prevalence of migraine in our coun-try is reported as 16.4%. Oxidative stress is assumed to play a role in the patho-physiology of migraine. In many recent studies conducted on individuals with migraine, serum Oxidative Stress Index (OSI), Total Antioxidant Status (TAS), Total Oxidant Status (TOS) values were analyzed and it was indicated that the balance shifts towards oxidative direction. Thiol-disulfide homeostasis, which is an oxidative stress marker, was described in recent years and has been shown to have vital importance on cellular functions. In the light of this information, we aimed to examine the role of oxidative stress in pathogenesis of migraine disease with new biomarkers. The study was conducted on 36 cases of 24 pa-tients (17 female, 7 male; mean age: 40.54±11.60) followed up with a migraine diagnosis and 12 people in the healthy control group with similar age and sex (10 female, 2 male; mean age: 38.17±10.80). Total thiol (μmol/L), native thiol (μmol/L) and disulfide level, disulfide/native thiol, disulfide/total thiol, native thiol/total thiol ratios were quantified in the patient and control groups. In the migraine group with aura, reduced ratio and thiol oxidation reduction ratio val-ues were high and oxidized thiol ratio values were low (p = 0.010, 0.015, 0.048). This study focused on thiol-disulfide hemostasis, a new and reliable indicator in determining oxidative stress which is held responsible for the pathophysiology of migraine.

References

  • Alp R, Selek Ş, Alp Sİ, Taşkın A, Koçyiğit A., 2010. Oxidative and antioxidative balance in patients of migraine. Eur Rev Med Pharmacol Sci. 14:877-882.
  • Atmaca G., 2004. Antioxidant effects of sulfur-containing amino acids. Yonsei Med J. 45:776–788.
  • Bektas H, Vural G, Gumusyayla S, Deniz O, Alisik M, Erel O., 2016. Dynamic thiol–disulfide homeostasis in acute ischemic stroke patients. Acta Neurol Belg. 116:489–494.
  • Biswas S, Chida AS, Rahman I., 2006. Redox modifications of protein-thiols: emerging roles in cell signaling. BiochemPharmacol. 71:551-64. 23.
  • Blokhina O, Virolainen E, Fagerstedt KV., 2003. Antioxidants, Oxidative Damage and Oxygen Deprivation Stress: a Review. Annals of Botany. 91:179-94.
  • Bockwski L, Sobaniec W, Kulak W, et al., 2008. Serum and intraerythrocyte antioxidant enzymes and lipid peroxides in children with migraine. Pharmacol. 60:542–548.
  • Boran E, Bolay H., 2013. Migren Patofizyolojisi Nöropsikiyatri Arşivi. 50 Özel Sayı 1: 1-7.
  • Cadenas E., 1989. Biochemistry of oxygen toxicıty. Annu Rev Biochem. 58:79–110.
  • Circu ML, Aw TY. 2010. Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med. 48(6): 749–762.
  • Erel O., 2004. A novel automated direct measurement method fortotal antioxidant capacity using a new generation, morestable ABTS radical cation. Clin Biochem. 37:277–285.
  • Erel O, Neselioglu S., 2014. A novel and automated assay for thiol/disulphide homeostasis. ClinBiochem. 47:326-332.
  • Eren Y, Dirik E, Neselioglu S, Erel O., 2015. Oxidative stress and decreased thiol level in patients with migraine: cross-sectional study. Acta Neurol Belg. 115:643–649.
  • Erol I, Alehan F, Aldemir D, Ogus E., 2010. Increased vulnerability to oxidative stress in pediatric migraine patients, Pediatr Neurol. 43:21-24.
  • Ertas M, Baykan B, Orhan EK, Zarifoglu M, Karli N, Saip S et al., 2012. One-year prevalence and the impact of migraine and tension-type headache in Turkey: a nationwide home-based study in adults. J Headache Pain. 13(2):147-57.
  • Gruber HJ, Bernecker C, Lechner A, et al., 2010. Increased nitric oxide stress is associated with migraine. Cephalalgia. 30:486–492.
  • Headache Classification Committee of the International Headache Society., 2013. The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia. 33(9):629-808.
  • Hu ML., 1994. Measurement of protein thiol groups and glutathione in plasma. Methods Enzymol 233:380–385.
  • Jones DP, Liang Y., 2009. Measuring the poise of thiol/disulfide couples in vivo. Free Radic Biol Med. 15;47(10):1329-38.
  • Kayacan Y, Yazar H, Cerit G, Ghojebeigloo BE., 2019. A new oxidative stress indicator: Effect of 5-hydroxy tryptophan on thiol-disülfid homeostasis in exercise. Nutrition. 63-64:114-119.
  • Kayacan Y, Yazar H, Kısa EC, Ghojebeiglo BE., 2018. A novel biomarker explaining the role of oxidative stress in exercise and l-thyrosine supplementation: thiol/disulphide homeostasis. Arch Physiol Biochem. Jul;124(3):232-236.
  • Kundi H, Ates I, Kiziltunc E, Cetin M, Cicekcioglu H, Neselioglu S, et al. 2015. A novel oxidative stress marker in acute myocardial infarction; thiol/disulphide homeostasis. Am J EmergMed. Nov;33(11):1567-71.
  • Kurt ANC, Aydın A, Demir H, Erel O., 2017. Headache in children and dynamic thiol/disulfide balance evaluation with a new method. Neurol Sci. 38(8):1495–1499.
  • Lance JW., 1993. Current concepts of migraine pathogenesis. Neurology. 43:S11–S15
  • Matteucci E, Giampietro O., 2010. Thiol signalling network with an eye to diabetes. Molecules. 15:8890-903.25.
  • Méndez-Armenta M, Nava-Ruíz C, Juárez-Rebollar D, Rodríguez Martínez E, Gómez PY., 2014. Oxidative stress associated with neuronal apoptosis in experimental models of epilepsy. Oxidative med Cell Longev. 293689.
  • Noseda R, Burstein R., 2013. Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, CSD, sensitization and modulation of pain. Pain. 154 Supp 1:S44-53.
  • Oz A, Uguz AC., 2015. Migren patogenezinde oksidatif strese duyarlı TRP kanallarının rolleri. Med J SDU. 22(4):144-150.
  • Pasaoglu H, Sancak B, Bukan N., 2004. Lipid peroxidation and resistance to oxidation in patients with type 2 diabetes mellitus. Tohoku J Exp Med. 203:211–218.
  • Prabhu A, Sarcar B, Kahali S, Yuan Z, Johnson JJ, Adam KP et al., 2014. Cysteine catabolism: a novel metabolic pathway contributing to glioblastoma growth. CancerRes. 4(3): 787–796.
  • Reuter U, Bolay H, Jansen-Olesen I, Chiarugi A, Sanchez del Rio M, Letourneau R, et al., 2001. Delayed inflammation in rat meinges: implications for migraine pathophysiology. Brain. 124:2490-2502.
  • Rodrigues SD, Batista GB, Ingberman M, Pecoits-Filho R, Nakao LS., 2012. Plasma cysteine/cystine reduction potential correlates with plasma creatinine levels in chronic kidney disease. Blood Purif. 34(3–4): 231–237.
  • Sen CK, Packer L., 2000. Thiol homeostasis and supplements in physical exercise. Am J Clin Nutr. 72:653-69.
  • Sharma R, Macy S, Richardson K, Lokhnygina Y, Laskowitz DT., 2014. A blood-based biomarker panel to detect acute stroke. J Stroke Cerebrovasc Dis. 23(5):910–918.
  • Stewart WF, Lipton RB, Celentano DD, Reed ML., 1992. Prevalence of migraine headache in the United States. Relation to age, income, race and other sociodemographic factors. JAMA. 267;(1):64-9.
  • Tetik S, Ahmad S, Alturfan AA, Fresko I, Disbudak M, Sahin Y et al., 2010. Determination of oxidant stress in plasma of rheumatoid arthritis and primary osteoarthritis patients. Indian J Biochem Biophys. 47(6):353–358.
  • Tuncel D, Tolun FI, Gokce M. et al., 2008. Oxidative stress in migraine with and without aura. Biol Trace Elem Res 126:92–97.
  • Uzar E, Evliyaoglu O, Toprak G, Acar A, Yucel Y, Calisir T et al. 2011. Increased asymmetric dimethylarginine and nitric oxide levels in patients with migraine, J Headache Pain. 12:239–243.
  • Valko M, Leibfritz D, Moncola J, Cronin MTD, Mazura M, Telser J., 2007. Free radicals and antioxidants in normal physiological functions and human disease. The International Journal of Biochemistry & Cell Biology. 39(1):44-84.
  • Yılmaz G, Sürer H, Inan LE, Coşkun O, Yücel D., 2007. Increased nitrosative and oxidative stress in platelets of migraine patients. Tohoku J. Exp. Med. 211:23-30.
  • Yılmaz N, Aydın O, Yegin A, Tiltak A, Eren E, Aykal G., 2011. Impaired oxidative balance and association of blood glucose, insulin and HOMA-IR index in migraine. Biochemia Medica. 21(2):145–51.
  • Yılmaz N, Aydın O, Yegin A, Tiltak A, Eren E., 2011. Increased levels of total oxidant status and decreased activity of arylesterase in migraineurs, Clinical Biochemistry. 44;832–837.
There are 41 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Clinical Research
Authors

Aybala Neslihan Alagöz 0000-0003-4498-4817

Sıdıka Sinem Tasdemir This is me

Hayrullah Yazar

Yesim Guzey Aras

Nimet Ucaroglu Can This is me

Publication Date December 4, 2019
Submission Date July 12, 2019
Acceptance Date October 21, 2019
Published in Issue Year 2019 Volume: 36 Issue: 1

Cite

APA Alagöz, A. N., Tasdemir, S. S., Yazar, H., Guzey Aras, Y., et al. (2019). Thiol disulfide homeostasis as oxidative stress marker in migraine patients. Journal of Experimental and Clinical Medicine, 36(1), 1-8.
AMA Alagöz AN, Tasdemir SS, Yazar H, Guzey Aras Y, Ucaroglu Can N. Thiol disulfide homeostasis as oxidative stress marker in migraine patients. J. Exp. Clin. Med. December 2019;36(1):1-8.
Chicago Alagöz, Aybala Neslihan, Sıdıka Sinem Tasdemir, Hayrullah Yazar, Yesim Guzey Aras, and Nimet Ucaroglu Can. “Thiol Disulfide Homeostasis As Oxidative Stress Marker in Migraine Patients”. Journal of Experimental and Clinical Medicine 36, no. 1 (December 2019): 1-8.
EndNote Alagöz AN, Tasdemir SS, Yazar H, Guzey Aras Y, Ucaroglu Can N (December 1, 2019) Thiol disulfide homeostasis as oxidative stress marker in migraine patients. Journal of Experimental and Clinical Medicine 36 1 1–8.
IEEE A. N. Alagöz, S. S. Tasdemir, H. Yazar, Y. Guzey Aras, and N. Ucaroglu Can, “Thiol disulfide homeostasis as oxidative stress marker in migraine patients”, J. Exp. Clin. Med., vol. 36, no. 1, pp. 1–8, 2019.
ISNAD Alagöz, Aybala Neslihan et al. “Thiol Disulfide Homeostasis As Oxidative Stress Marker in Migraine Patients”. Journal of Experimental and Clinical Medicine 36/1 (December 2019), 1-8.
JAMA Alagöz AN, Tasdemir SS, Yazar H, Guzey Aras Y, Ucaroglu Can N. Thiol disulfide homeostasis as oxidative stress marker in migraine patients. J. Exp. Clin. Med. 2019;36:1–8.
MLA Alagöz, Aybala Neslihan et al. “Thiol Disulfide Homeostasis As Oxidative Stress Marker in Migraine Patients”. Journal of Experimental and Clinical Medicine, vol. 36, no. 1, 2019, pp. 1-8.
Vancouver Alagöz AN, Tasdemir SS, Yazar H, Guzey Aras Y, Ucaroglu Can N. Thiol disulfide homeostasis as oxidative stress marker in migraine patients. J. Exp. Clin. Med. 2019;36(1):1-8.