Research Article
BibTex RIS Cite
Year 2020, Volume: 37 Issue: 1, 5 - 10, 23.03.2020

Abstract

References

  • Allen, C. M. 1984. 'Predicting the outcome of acute stroke: a prognostic score', J Neurol Neurosurg Psychiatry, 47: 475-80.
  • Benetos, A., S. Laurent, R. G. Asmar, and P. Lacolley. 1997. 'Large artery stiffness in hypertension', J Hypertens Suppl, 15: S89-97.
  • Bonardo, P., F. Pantiu, M. Ferraro, A. Chertcoff, L. Bandeo, L. L. Cejas, S. Pacha, C. U. Roca, C. Rugilo, M. M. F. Pardal, and R. Reisin. 2018. 'Impact of Infarct Size on Blood Pressure in Young Patients with Acute Stroke', J Vasc Interv Neurol, 10: 14-16.
  • Chang, A., B. Ricci, B. M. Grory, S. Cutting, T. Burton, K. Dakay, M. Jayaraman, A. Merkler, M. Reznik, M. P. Lerario, C. Song, H. Kamel, M. S. V. Elkind, K. Furie, and S. Yaghi. 2019. 'Cardiac Biomarkers Predict Large Vessel Occlusion in Patients with Ischemic Stroke', J Stroke Cerebrovasc Dis, 28: 1726-31.
  • Drozdowska, B. A., S. Singh, and T. J. Quinn. 2019. 'Thinking About the Future: A Review of Prognostic Scales Used in Acute Stroke', Front Neurol, 10: 274.
  • Fiorelli, M., A. Alperovitch, C. Argentino, M. L. Sacchetti, D. Toni, G. Sette, C. Cavalletti, M. C. Gori, and C. Fieschi. 1995. 'Prediction of long-term outcome in the early hours following acute ischemic stroke. Italian Acute Stroke Study Group', Arch Neurol, 52: 250-5.
  • Fullerton, K. J., G. Mackenzie, and R. W. Stout. 1988. 'Prognostic indices in stroke', Q J Med, 66: 147-62.
  • Gompertz, P., P. Pound, and S. Ebrahim. 1994. 'Predicting stroke outcome: Guy's prognostic score in practice', J Neurol Neurosurg Psychiatry, 57: 932-5.
  • Hendrix, P., N. Sofoluke, M. D. Adams, S. Kunaprayoon, R. Zand, A. N. Kolinovsky, T. N. Person, M. Gupta, O. Goren, C. M. Schirmer, N. S. Rost, J. E. Faber, and C. J. Griessenauer. 2019. 'Risk Factors for Acute Ischemic Stroke Caused by Anterior Large Vessel Occlusion', Stroke, 50: 1074-80.
  • Kim, W. J., H. W. Nah, D. H. Kim, and J. K. Cha. 2016. 'Association between Left Ventricular Dysfunction and Functional Outcomes at Three Months in Acute Ischemic Stroke', J Stroke Cerebrovasc Dis, 25: 2247-52.
  • Kwok, C. S., J. F. Potter, G. Dalton, A. George, A. K. Metcalf, J. Ngeh, A. Nicolson, P. Owusu-Agyei, R. Shekhar, K. Walsh, E. A. Warburton, and P. K. Myint. 2013. 'The SOAR stroke score predicts inpatient and 7-day mortality in acute stroke', Stroke, 44: 2010-2.
  • Lazar, J., D. Busch, E. Wirkowski, L. T. Clark, and L. Salciccioli. 2008. 'Changes in QT dispersion after thrombolysis for stroke', Int J Cardiol, 125: 258-62.
  • Lederman, Y. S., C. Balucani, J. Lazar, L. Steinberg, J. Gugger, and S. R. Levine. 2014. 'Relationship between QT interval dispersion in acute stroke and stroke prognosis: a systematic review', J Stroke Cerebrovasc Dis, 23: 2467-78.
  • Lederman, Y. S., C. Balucani, L. R. Steinberg, C. Philip, J. M. Lazar, J. Weedon, G. Mirchandani, S. Z. Weingast, G. Viticchi, L. Falsetti, M. Silvestrini, J. J. Gugger, D. Aharonoff, P. Piran, Z. Adler, and S. R. Levine. 2019. 'Does the Magnitude of the Electrocardiogram QT Interval Dispersion Predict Stroke Outcome?', J Stroke Cerebrovasc Dis, 28: 44-48.
  • Li, T., J. Zhu, Q. Fang, X. Duan, M. Zhang, S. Diao, Y. Zhou, S. Yang, Y. Kong, and X. Cai. 2018. 'Association of H-Type Hypertension with Stroke Severity and Prognosis', Biomed Res Int, 2018: 8725908.
  • Lindsberg, P. J., and R. O. Roine. 2004. 'Hyperglycemia in acute stroke', Stroke, 35: 363-4.
  • Lyden, P. 2017. 'Using the National Institutes of Health Stroke Scale: A Cautionary Tale', Stroke, 48: 513-19.
  • Mathisen, S. M., I. Dalen, J. P. Larsen, and M. Kurz. 2016. 'Long-Term Mortality and Its Risk Factors in Stroke Survivors', J Stroke Cerebrovasc Dis, 25: 635-41.
  • Mazza, A., A. C. Pessina, P. Gianluca, V. Tikhonoff, A. Pavei, and E. Casiglia. 2001. 'Pulse pressure: an independent predictor of coronary and stroke mortality in elderly females from the general population', Blood Press, 10: 205-11.
  • Milionis, H., M. Faouzi, M. Cordier, S. D'Ambrogio-Remillard, A. Eskandari, and P. Michel. 2013. 'Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction', Int J Cardiol, 168: 1082-7.
  • Millar, J. A., A. F. Lever, and V. Burke. 1999. 'Pulse pressure as a risk factor for cardiovascular events in the MRC Mild Hypertension Trial', J Hypertens, 17: 1065-72.
  • Mostofsky, E., G. A. Wellenius, A. Noheria, E. B. Levitan, M. R. Burger, G. Schlaug, and M. A. Mittleman. 2009. 'Renal function predicts survival in patients with acute ischemic stroke', Cerebrovasc Dis, 28: 88-94.
  • Muscari, A., G. M. Puddu, N. Santoro, and M. Zoli. 2011. 'A simple scoring system for outcome prediction of ischemic stroke', Acta Neurol Scand, 124: 334-42.
  • Ntaios, G., M. Faouzi, J. Ferrari, W. Lang, K. Vemmos, and P. Michel. 2012. 'An integer-based score to predict functional outcome in acute ischemic stroke: the ASTRAL score', Neurology, 78: 1916-22.
  • Racosta, J. M., F. Di Guglielmo, F. R. Klein, P. M. Riccio, F. M. Giacomelli, M. E. Gonzalez Toledo, F. Pagani Cassara, A. Tamargo, M. Delfitto, and L. A. Sposato. 2014. 'Stroke Severity Score based on Six Signs and Symptoms The 6S Score: A Simple Tool for Assessing Stroke Severity and In-hospital Mortality', J Stroke, 16: 178-83.
  • Ripoll, J. G., J. L. Blackshear, and J. L. Diaz-Gomez. 2018. 'Acute Cardiac Complications in Critical Brain Disease', Neurosurg Clin N Am, 29: 281-97.
  • Rodrigues, C. J., and V. R. Joshi. 1991. 'Predicting the immediate outcome of patients with cerebrovascular accident: a prognostic score', J Assoc Physicians India, 39: 175-80.
  • Ryu, W. S., E. K. Bae, S. H. Park, S. W. Jeong, D. Schellingerhout, M. Nahrendorf, and D. E. Kim. 2018. 'Increased Left Ventricular Filling Pressure and Arterial Occlusion in Stroke Related to Atrial Fibrillation', J Stroke Cerebrovasc Dis, 27: 1275-82.
  • Sacco, R. L., S. E. Kasner, J. P. Broderick, L. R. Caplan, J. J. Connors, A. Culebras, M. S. Elkind, M. G. George, A. D. Hamdan, R. T. Higashida, B. L. Hoh, L. S. Janis, C. S. Kase, D. O. Kleindorfer, J. M. Lee, M. E. Moseley, E. D. Peterson, T. N. Turan, A. L. Valderrama, and H. V. Vinters. 2013. 'An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association', Stroke, 44: 2064-89.
  • Soliman, R. H., M. I. Oraby, M. Fathy, and A. M. Essam. 2018. 'Risk factors of acute ischemic stroke in patients presented to Beni-Suef University Hospital: prevalence and relation to stroke severity at presentation', Egypt J Neurol Psychiatr Neurosurg, 54: 8.
  • Sung, P. H., K. H. Chen, H. S. Lin, C. H. Chu, J. Y. Chiang, and H. K. Yip. 2019. 'The Correlation between Severity of Neurological Impairment and Left Ventricular Function in Patients after Acute Ischemic Stroke', J Clin Med, 8.
  • Sung, S. F., Y. W. Chen, L. C. Hung, and H. J. Lin. 2014. 'Revised iScore to predict outcomes after acute ischemic stroke', J Stroke Cerebrovasc Dis, 23: 1634-9.
  • Verdecchia, P., G. Schillaci, G. Reboldi, S. S. Franklin, and C. Porcellati. 2001. 'Different prognostic impact of 24-hour mean blood pressure and pulse pressure on stroke and coronary artery disease in essential hypertension', Circulation, 103: 2579-84.
  • Wade, D. T., C. E. Skilbeck, V. A. Wood, and R. Langton Hewer. 1984. 'Long-term survival after stroke', Age Ageing, 13: 76-82.
  • Wu, C. Y., H. M. Wu, J. D. Lee, and H. H. Weng. 2010. 'Stroke risk factors and subtypes in different age groups: a hospital-based study', Neurol India, 58: 863-8.
  • Zheng, L., Z. Sun, J. Li, R. Zhang, X. Zhang, S. Liu, J. Li, C. Xu, D. Hu, and Y. Sun. 2008. 'Pulse pressure and mean arterial pressure in relation to ischemic stroke among patients with uncontrolled hypertension in rural areas of China', Stroke, 39: 1932-7.

The relationship between musekna index and stroke severity in patients with acute ischemic stroke

Year 2020, Volume: 37 Issue: 1, 5 - 10, 23.03.2020

Abstract

Acute stroke is an important cause of morbidity and mortality. Prediction tools are especially helpful in this situation in guiding for medical treatment decision. It is found that prognostic index is predictor of mortality and heart failure in patients with ischemic heart failure implanted with an ICD, the prognostic index (PI) being built according to the formula: 120 - age + mean 24 h systolic blood pressure - (creatinine * 10). However, a mean 24 h systolic blood pressure calculation is not clinically easy. Therefore, we propose a new modified prognostic index (Musekna Index). Musekna Index (MI) was calculated as “120 - age + mean arterial pressure - (creatinine * 10)”. In this study, we aimed to investigate the relationship between MI and stroke severity in patients with acute ischemic stroke. This cross-sectional study included 162 patients (males, 64; females, 98; 67 ± 15 years) with acute ischemic stroke. Patients were divided into two groups based on the calculated National Institutes of Health Stroke Scale (NIHSS) score (Group 1, NIHSS score < 16; Group 2, NIHSS score ≥ 16). Demographic, clinical, and laboratory data for all patients were collected. Musekna Index (Modified Prognostic Index) was calculated as “120 - age + mean arterial pressure - (creatinine * 10)”. MI index was calculated admission to the neurology care unit. Echocardiographic examinations were performed using the parasternal longitudinal axis and apical 4-chamber windows in accordance with the recommendations of the American Echocardiography Committee. There were no significant differences among the demographic parameters of patients. MI was significantly higher in Group 1 patients than in Group 2 patients (139±15.6 vs 132±13.7, p=0.028). Our results suggest that MI is associated with stroke severity on admission in patients with acute ischemic stroke. 

References

  • Allen, C. M. 1984. 'Predicting the outcome of acute stroke: a prognostic score', J Neurol Neurosurg Psychiatry, 47: 475-80.
  • Benetos, A., S. Laurent, R. G. Asmar, and P. Lacolley. 1997. 'Large artery stiffness in hypertension', J Hypertens Suppl, 15: S89-97.
  • Bonardo, P., F. Pantiu, M. Ferraro, A. Chertcoff, L. Bandeo, L. L. Cejas, S. Pacha, C. U. Roca, C. Rugilo, M. M. F. Pardal, and R. Reisin. 2018. 'Impact of Infarct Size on Blood Pressure in Young Patients with Acute Stroke', J Vasc Interv Neurol, 10: 14-16.
  • Chang, A., B. Ricci, B. M. Grory, S. Cutting, T. Burton, K. Dakay, M. Jayaraman, A. Merkler, M. Reznik, M. P. Lerario, C. Song, H. Kamel, M. S. V. Elkind, K. Furie, and S. Yaghi. 2019. 'Cardiac Biomarkers Predict Large Vessel Occlusion in Patients with Ischemic Stroke', J Stroke Cerebrovasc Dis, 28: 1726-31.
  • Drozdowska, B. A., S. Singh, and T. J. Quinn. 2019. 'Thinking About the Future: A Review of Prognostic Scales Used in Acute Stroke', Front Neurol, 10: 274.
  • Fiorelli, M., A. Alperovitch, C. Argentino, M. L. Sacchetti, D. Toni, G. Sette, C. Cavalletti, M. C. Gori, and C. Fieschi. 1995. 'Prediction of long-term outcome in the early hours following acute ischemic stroke. Italian Acute Stroke Study Group', Arch Neurol, 52: 250-5.
  • Fullerton, K. J., G. Mackenzie, and R. W. Stout. 1988. 'Prognostic indices in stroke', Q J Med, 66: 147-62.
  • Gompertz, P., P. Pound, and S. Ebrahim. 1994. 'Predicting stroke outcome: Guy's prognostic score in practice', J Neurol Neurosurg Psychiatry, 57: 932-5.
  • Hendrix, P., N. Sofoluke, M. D. Adams, S. Kunaprayoon, R. Zand, A. N. Kolinovsky, T. N. Person, M. Gupta, O. Goren, C. M. Schirmer, N. S. Rost, J. E. Faber, and C. J. Griessenauer. 2019. 'Risk Factors for Acute Ischemic Stroke Caused by Anterior Large Vessel Occlusion', Stroke, 50: 1074-80.
  • Kim, W. J., H. W. Nah, D. H. Kim, and J. K. Cha. 2016. 'Association between Left Ventricular Dysfunction and Functional Outcomes at Three Months in Acute Ischemic Stroke', J Stroke Cerebrovasc Dis, 25: 2247-52.
  • Kwok, C. S., J. F. Potter, G. Dalton, A. George, A. K. Metcalf, J. Ngeh, A. Nicolson, P. Owusu-Agyei, R. Shekhar, K. Walsh, E. A. Warburton, and P. K. Myint. 2013. 'The SOAR stroke score predicts inpatient and 7-day mortality in acute stroke', Stroke, 44: 2010-2.
  • Lazar, J., D. Busch, E. Wirkowski, L. T. Clark, and L. Salciccioli. 2008. 'Changes in QT dispersion after thrombolysis for stroke', Int J Cardiol, 125: 258-62.
  • Lederman, Y. S., C. Balucani, J. Lazar, L. Steinberg, J. Gugger, and S. R. Levine. 2014. 'Relationship between QT interval dispersion in acute stroke and stroke prognosis: a systematic review', J Stroke Cerebrovasc Dis, 23: 2467-78.
  • Lederman, Y. S., C. Balucani, L. R. Steinberg, C. Philip, J. M. Lazar, J. Weedon, G. Mirchandani, S. Z. Weingast, G. Viticchi, L. Falsetti, M. Silvestrini, J. J. Gugger, D. Aharonoff, P. Piran, Z. Adler, and S. R. Levine. 2019. 'Does the Magnitude of the Electrocardiogram QT Interval Dispersion Predict Stroke Outcome?', J Stroke Cerebrovasc Dis, 28: 44-48.
  • Li, T., J. Zhu, Q. Fang, X. Duan, M. Zhang, S. Diao, Y. Zhou, S. Yang, Y. Kong, and X. Cai. 2018. 'Association of H-Type Hypertension with Stroke Severity and Prognosis', Biomed Res Int, 2018: 8725908.
  • Lindsberg, P. J., and R. O. Roine. 2004. 'Hyperglycemia in acute stroke', Stroke, 35: 363-4.
  • Lyden, P. 2017. 'Using the National Institutes of Health Stroke Scale: A Cautionary Tale', Stroke, 48: 513-19.
  • Mathisen, S. M., I. Dalen, J. P. Larsen, and M. Kurz. 2016. 'Long-Term Mortality and Its Risk Factors in Stroke Survivors', J Stroke Cerebrovasc Dis, 25: 635-41.
  • Mazza, A., A. C. Pessina, P. Gianluca, V. Tikhonoff, A. Pavei, and E. Casiglia. 2001. 'Pulse pressure: an independent predictor of coronary and stroke mortality in elderly females from the general population', Blood Press, 10: 205-11.
  • Milionis, H., M. Faouzi, M. Cordier, S. D'Ambrogio-Remillard, A. Eskandari, and P. Michel. 2013. 'Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction', Int J Cardiol, 168: 1082-7.
  • Millar, J. A., A. F. Lever, and V. Burke. 1999. 'Pulse pressure as a risk factor for cardiovascular events in the MRC Mild Hypertension Trial', J Hypertens, 17: 1065-72.
  • Mostofsky, E., G. A. Wellenius, A. Noheria, E. B. Levitan, M. R. Burger, G. Schlaug, and M. A. Mittleman. 2009. 'Renal function predicts survival in patients with acute ischemic stroke', Cerebrovasc Dis, 28: 88-94.
  • Muscari, A., G. M. Puddu, N. Santoro, and M. Zoli. 2011. 'A simple scoring system for outcome prediction of ischemic stroke', Acta Neurol Scand, 124: 334-42.
  • Ntaios, G., M. Faouzi, J. Ferrari, W. Lang, K. Vemmos, and P. Michel. 2012. 'An integer-based score to predict functional outcome in acute ischemic stroke: the ASTRAL score', Neurology, 78: 1916-22.
  • Racosta, J. M., F. Di Guglielmo, F. R. Klein, P. M. Riccio, F. M. Giacomelli, M. E. Gonzalez Toledo, F. Pagani Cassara, A. Tamargo, M. Delfitto, and L. A. Sposato. 2014. 'Stroke Severity Score based on Six Signs and Symptoms The 6S Score: A Simple Tool for Assessing Stroke Severity and In-hospital Mortality', J Stroke, 16: 178-83.
  • Ripoll, J. G., J. L. Blackshear, and J. L. Diaz-Gomez. 2018. 'Acute Cardiac Complications in Critical Brain Disease', Neurosurg Clin N Am, 29: 281-97.
  • Rodrigues, C. J., and V. R. Joshi. 1991. 'Predicting the immediate outcome of patients with cerebrovascular accident: a prognostic score', J Assoc Physicians India, 39: 175-80.
  • Ryu, W. S., E. K. Bae, S. H. Park, S. W. Jeong, D. Schellingerhout, M. Nahrendorf, and D. E. Kim. 2018. 'Increased Left Ventricular Filling Pressure and Arterial Occlusion in Stroke Related to Atrial Fibrillation', J Stroke Cerebrovasc Dis, 27: 1275-82.
  • Sacco, R. L., S. E. Kasner, J. P. Broderick, L. R. Caplan, J. J. Connors, A. Culebras, M. S. Elkind, M. G. George, A. D. Hamdan, R. T. Higashida, B. L. Hoh, L. S. Janis, C. S. Kase, D. O. Kleindorfer, J. M. Lee, M. E. Moseley, E. D. Peterson, T. N. Turan, A. L. Valderrama, and H. V. Vinters. 2013. 'An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association', Stroke, 44: 2064-89.
  • Soliman, R. H., M. I. Oraby, M. Fathy, and A. M. Essam. 2018. 'Risk factors of acute ischemic stroke in patients presented to Beni-Suef University Hospital: prevalence and relation to stroke severity at presentation', Egypt J Neurol Psychiatr Neurosurg, 54: 8.
  • Sung, P. H., K. H. Chen, H. S. Lin, C. H. Chu, J. Y. Chiang, and H. K. Yip. 2019. 'The Correlation between Severity of Neurological Impairment and Left Ventricular Function in Patients after Acute Ischemic Stroke', J Clin Med, 8.
  • Sung, S. F., Y. W. Chen, L. C. Hung, and H. J. Lin. 2014. 'Revised iScore to predict outcomes after acute ischemic stroke', J Stroke Cerebrovasc Dis, 23: 1634-9.
  • Verdecchia, P., G. Schillaci, G. Reboldi, S. S. Franklin, and C. Porcellati. 2001. 'Different prognostic impact of 24-hour mean blood pressure and pulse pressure on stroke and coronary artery disease in essential hypertension', Circulation, 103: 2579-84.
  • Wade, D. T., C. E. Skilbeck, V. A. Wood, and R. Langton Hewer. 1984. 'Long-term survival after stroke', Age Ageing, 13: 76-82.
  • Wu, C. Y., H. M. Wu, J. D. Lee, and H. H. Weng. 2010. 'Stroke risk factors and subtypes in different age groups: a hospital-based study', Neurol India, 58: 863-8.
  • Zheng, L., Z. Sun, J. Li, R. Zhang, X. Zhang, S. Liu, J. Li, C. Xu, D. Hu, and Y. Sun. 2008. 'Pulse pressure and mean arterial pressure in relation to ischemic stroke among patients with uncontrolled hypertension in rural areas of China', Stroke, 39: 1932-7.
There are 36 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Clinical Research
Authors

Ünal Öztürk 0000-0002-8341-5070

Önder Öztürk

Yusuf Tamam This is me

Publication Date March 23, 2020
Submission Date January 10, 2020
Acceptance Date January 30, 2020
Published in Issue Year 2020 Volume: 37 Issue: 1

Cite

APA Öztürk, Ü., Öztürk, Ö., & Tamam, Y. (2020). The relationship between musekna index and stroke severity in patients with acute ischemic stroke. Journal of Experimental and Clinical Medicine, 37(1), 5-10.
AMA Öztürk Ü, Öztürk Ö, Tamam Y. The relationship between musekna index and stroke severity in patients with acute ischemic stroke. J. Exp. Clin. Med. March 2020;37(1):5-10.
Chicago Öztürk, Ünal, Önder Öztürk, and Yusuf Tamam. “The Relationship Between Musekna Index and Stroke Severity in Patients With Acute Ischemic Stroke”. Journal of Experimental and Clinical Medicine 37, no. 1 (March 2020): 5-10.
EndNote Öztürk Ü, Öztürk Ö, Tamam Y (March 1, 2020) The relationship between musekna index and stroke severity in patients with acute ischemic stroke. Journal of Experimental and Clinical Medicine 37 1 5–10.
IEEE Ü. Öztürk, Ö. Öztürk, and Y. Tamam, “The relationship between musekna index and stroke severity in patients with acute ischemic stroke”, J. Exp. Clin. Med., vol. 37, no. 1, pp. 5–10, 2020.
ISNAD Öztürk, Ünal et al. “The Relationship Between Musekna Index and Stroke Severity in Patients With Acute Ischemic Stroke”. Journal of Experimental and Clinical Medicine 37/1 (March 2020), 5-10.
JAMA Öztürk Ü, Öztürk Ö, Tamam Y. The relationship between musekna index and stroke severity in patients with acute ischemic stroke. J. Exp. Clin. Med. 2020;37:5–10.
MLA Öztürk, Ünal et al. “The Relationship Between Musekna Index and Stroke Severity in Patients With Acute Ischemic Stroke”. Journal of Experimental and Clinical Medicine, vol. 37, no. 1, 2020, pp. 5-10.
Vancouver Öztürk Ü, Öztürk Ö, Tamam Y. The relationship between musekna index and stroke severity in patients with acute ischemic stroke. J. Exp. Clin. Med. 2020;37(1):5-10.