Evaluation of clinical, laboratory characteristics and treatment modalities of pituitary adenomas: single center experience

Year 2021, Volume: 38 Issue: 4, 404 - 409, 09.10.2021

Ayşe Özdemir Yavuz Elif Kılıç Kan Ramis Çolak

Abstract

Pituitary adenoma is a group of disease with a broad different clinical characteristics and complications. We aimed to present the data of patients being followed in a single center and discuss the pituitary adenomas based on the lierature. Two hundreds and twenty patients followed at Department of Endocrinology and Metabolism, Medical School of Ondokuz Mayis University, were included into study. Clinical characterisitics, laboratory findings and treatment modalities were examined retrospectively. 59% of patients were female and 41% were male. Mean age during the diagnosis was 43.7 years. 62% of the adenoma was macroadenoma. 73% of adenomas was functional. Among the functional adenomas, the most seen types were prolactin-secreting adenoma and growth-hormone secreting adenoma. 67% surgical treatment, 20% medical treatment and 7% radiotherapy were applied to our patients. Post-operative complications were developed in 21 of patiens. In patients with non-functional adenoma, the cure after surgery was detected as 19.6% and the remission after the surgery was detected as 8.9%. In this study, the characteristics of the pituitary adenomas were found similar to the literature generally. The early diagnosis of the disease has a significant importance in terms of treatment and the response to the treatment.

Keywords

Pituitary adenoma, prolactinoma, , acromegaly, cushing disease

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