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Year 2022, Volume: 39 Issue: 2, 409 - 413, 18.03.2022

Abstract

References

  • 1. World Health Organization. Weekly epidemiological update - 29 December 2020, https://www.who.int/publications/m/item/weekly-epidemiological-update---29-december- 2020 [Accessed at 10 January 2020].
  • 2. Yu N, Li W, Kong Q, Xiang Z, Wang S, Lin X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet 2020;395(10223):497–506.
  • 3. Schwartz D. The Effects of Pregnancy on Women with COVID-19: Maternal and Infant Outcomes. Clin Infect Dis 2020;71(16):2042–4.
  • 4. Trad APA, Ibirogba ER, Elrefaei A, Narang K, Tonni G, Picone O, et al. Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence? Hypertens Pregnancy [Internet] 2020;39(3):361–9.
  • 5. Qiancheng X, Jian S, Lingling P, Lei H, Xiaogan J, Weihua L, et al. Coronavirus disease 2019 and pregnancy. Int J Infect Dis 2020;95:376–83.
  • 6. Zaigham M, and Andersson O. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies. Acta Obstet Gynecol Scand 2020;99(7):823–9.
  • 7. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020;20(8):727–33.
  • 8. Xiang N, Havers F, Chen T, Song Y, Tu W, Li Let al. Use of National Pneumonia Surveillance to Describe Influenza A(H7N9) Virus Epidemiology, China, 2004–2013. Emerg Infect Dis 2013;19(11):1784–90.
  • 9. Weinkove R, McQuilten Z, Adler J, Agar, M, Blith E, Cheng AC, et al. Haematology & Oncology COVID-19 Interim Guidance Version 3.0 19. Med J Aust 2020;212(10):481–9.
  • 10. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506.
  • 11. He HYQDB, Feng YP and Sun WH. The prognostic value of preoperative NLR , d-NLR , PLR and LMR for predicting clinical outcome in surgical colorectal cancer patients. Med Oncol 2014;31(12):305.
  • 12. Seyit M, Avci E, Nar R, Senol H, Yilmaz A, Ozen M, et al. Neutrophil to lymphocyte ratio, lymphocyte to monocyte ratio and platelet to lymphocyte ratio to predict the severity of COVID-19. Am J Emerg Med [Internet] 2021;40:110-4.
  • 13. Shang W, Dong J, Ren Y, Tian M, Li W, Hu J, et al. The value of clinical parameters in predicting the severity of COVID-19. J Med Virol 2020;92(10):2188–92.
  • 14. Yang A, Liu J, Tao W and Li H. The diagnostic and predictive role of NLR , d-NLR and PLR in COVID-19 patients. Int Immunopharmacol 2020;84:106504.
  • 15. Erol Koç EM, Flndlk RB, Akkaya H, Karadaǧ I, Tokalloǧlu EÖ and Tekin ÖM. Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort. J Perinat Med 2021;49(2):141–7.
  • 16. Khartabil TA, Russcher H, van der Ven A and Rijke YB. A summary of the diagnostic and prognostic value of hemocytometry markers in COVID-19 patients. Critical Reviews in Clinical Laboratory Sciences, 57:6, 415-431.
  • 17. Chandra S, Tripathi AK, Mishra S, Amzarul M and Vaish AK. Physiological changes in hematological parameters during pregnancy. Indian J Hematol Blood Transfus 2012;28(3):144–6.
  • 18. Axell-house DB, Lavingia R, Rafferty M and Clark E. The estimation of diagnostic accuracy of tests for COVID-19: A scoping review. J Infect 2020;81:681–79.

Effect of complete blood count parameters on the clinical course of COVID-19 in pregnant women

Year 2022, Volume: 39 Issue: 2, 409 - 413, 18.03.2022

Abstract

Objective: Coronovirus Disease-19 (COVID-19) pandemic, affected pregnant women as well as many people. Aim of this study is to compare complete blood count (CBC) parameters of pregnant women infected with COVID-19 to that of healthy pregnant women and determine their prognostic features.
Materials and methods: 142 pregnant women infected with COVID-19 and 46 healthy pregnant women, included in this retrospective case-control study. Patients infected with COVID-19 were grouped as mild, moderate and severe, according to the findings of oxygen saturation and lung involvement. Age, gestational age, gravida, hospitalization length and CBC parameters of the participants were compared, according to the groups.
Results: CBC test revealed that uninfected pregnant women had statistically lower level of white blood cell count (WBC, p=0.001), platelet count (p=0,024), neutrophil count (p=0,001), lymphocytes (p=0,005), monocytes (p=0,001) and platelecrit (p=0.007) than from infected pregnant women. Evaluation of pregnant women with COVID-19 grouped into 3 categories as mild, moderate and severe showed that age, gravida and hospitalization length were comparable between groups, WBC (p=0.012) and neutrophile (p=0.001) counts of mild group were significantly lower than moderate group and there was no significant difference between moderate and severe groups regarding WBC and neutrophile counts (respectively p=0,281, p=0.542).
Conclusion: CBC analysis is simple, applicable, widely used and cheap laboratory method. CBC parameters seem as a candidate for predicting COVID-19 clinical course. However, larger sample sized prospective studies supporting this idea are required.

References

  • 1. World Health Organization. Weekly epidemiological update - 29 December 2020, https://www.who.int/publications/m/item/weekly-epidemiological-update---29-december- 2020 [Accessed at 10 January 2020].
  • 2. Yu N, Li W, Kong Q, Xiang Z, Wang S, Lin X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet 2020;395(10223):497–506.
  • 3. Schwartz D. The Effects of Pregnancy on Women with COVID-19: Maternal and Infant Outcomes. Clin Infect Dis 2020;71(16):2042–4.
  • 4. Trad APA, Ibirogba ER, Elrefaei A, Narang K, Tonni G, Picone O, et al. Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence? Hypertens Pregnancy [Internet] 2020;39(3):361–9.
  • 5. Qiancheng X, Jian S, Lingling P, Lei H, Xiaogan J, Weihua L, et al. Coronavirus disease 2019 and pregnancy. Int J Infect Dis 2020;95:376–83.
  • 6. Zaigham M, and Andersson O. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies. Acta Obstet Gynecol Scand 2020;99(7):823–9.
  • 7. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020;20(8):727–33.
  • 8. Xiang N, Havers F, Chen T, Song Y, Tu W, Li Let al. Use of National Pneumonia Surveillance to Describe Influenza A(H7N9) Virus Epidemiology, China, 2004–2013. Emerg Infect Dis 2013;19(11):1784–90.
  • 9. Weinkove R, McQuilten Z, Adler J, Agar, M, Blith E, Cheng AC, et al. Haematology & Oncology COVID-19 Interim Guidance Version 3.0 19. Med J Aust 2020;212(10):481–9.
  • 10. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506.
  • 11. He HYQDB, Feng YP and Sun WH. The prognostic value of preoperative NLR , d-NLR , PLR and LMR for predicting clinical outcome in surgical colorectal cancer patients. Med Oncol 2014;31(12):305.
  • 12. Seyit M, Avci E, Nar R, Senol H, Yilmaz A, Ozen M, et al. Neutrophil to lymphocyte ratio, lymphocyte to monocyte ratio and platelet to lymphocyte ratio to predict the severity of COVID-19. Am J Emerg Med [Internet] 2021;40:110-4.
  • 13. Shang W, Dong J, Ren Y, Tian M, Li W, Hu J, et al. The value of clinical parameters in predicting the severity of COVID-19. J Med Virol 2020;92(10):2188–92.
  • 14. Yang A, Liu J, Tao W and Li H. The diagnostic and predictive role of NLR , d-NLR and PLR in COVID-19 patients. Int Immunopharmacol 2020;84:106504.
  • 15. Erol Koç EM, Flndlk RB, Akkaya H, Karadaǧ I, Tokalloǧlu EÖ and Tekin ÖM. Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort. J Perinat Med 2021;49(2):141–7.
  • 16. Khartabil TA, Russcher H, van der Ven A and Rijke YB. A summary of the diagnostic and prognostic value of hemocytometry markers in COVID-19 patients. Critical Reviews in Clinical Laboratory Sciences, 57:6, 415-431.
  • 17. Chandra S, Tripathi AK, Mishra S, Amzarul M and Vaish AK. Physiological changes in hematological parameters during pregnancy. Indian J Hematol Blood Transfus 2012;28(3):144–6.
  • 18. Axell-house DB, Lavingia R, Rafferty M and Clark E. The estimation of diagnostic accuracy of tests for COVID-19: A scoping review. J Infect 2020;81:681–79.
There are 18 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Clinical Research
Authors

Zehra Yılmaz 0000-0003-1162-8648

Huri Güvey 0000-0002-8603-6981

Samettin Çelik 0000-0002-6407-1129

Canan Soyer Çalışkan 0000-0002-9889-5249

Early Pub Date March 18, 2022
Publication Date March 18, 2022
Submission Date September 8, 2021
Acceptance Date November 16, 2021
Published in Issue Year 2022 Volume: 39 Issue: 2

Cite

APA Yılmaz, Z., Güvey, H., Çelik, S., Soyer Çalışkan, C. (2022). Effect of complete blood count parameters on the clinical course of COVID-19 in pregnant women. Journal of Experimental and Clinical Medicine, 39(2), 409-413.
AMA Yılmaz Z, Güvey H, Çelik S, Soyer Çalışkan C. Effect of complete blood count parameters on the clinical course of COVID-19 in pregnant women. J. Exp. Clin. Med. March 2022;39(2):409-413.
Chicago Yılmaz, Zehra, Huri Güvey, Samettin Çelik, and Canan Soyer Çalışkan. “Effect of Complete Blood Count Parameters on the Clinical Course of COVID-19 in Pregnant Women”. Journal of Experimental and Clinical Medicine 39, no. 2 (March 2022): 409-13.
EndNote Yılmaz Z, Güvey H, Çelik S, Soyer Çalışkan C (March 1, 2022) Effect of complete blood count parameters on the clinical course of COVID-19 in pregnant women. Journal of Experimental and Clinical Medicine 39 2 409–413.
IEEE Z. Yılmaz, H. Güvey, S. Çelik, and C. Soyer Çalışkan, “Effect of complete blood count parameters on the clinical course of COVID-19 in pregnant women”, J. Exp. Clin. Med., vol. 39, no. 2, pp. 409–413, 2022.
ISNAD Yılmaz, Zehra et al. “Effect of Complete Blood Count Parameters on the Clinical Course of COVID-19 in Pregnant Women”. Journal of Experimental and Clinical Medicine 39/2 (March 2022), 409-413.
JAMA Yılmaz Z, Güvey H, Çelik S, Soyer Çalışkan C. Effect of complete blood count parameters on the clinical course of COVID-19 in pregnant women. J. Exp. Clin. Med. 2022;39:409–413.
MLA Yılmaz, Zehra et al. “Effect of Complete Blood Count Parameters on the Clinical Course of COVID-19 in Pregnant Women”. Journal of Experimental and Clinical Medicine, vol. 39, no. 2, 2022, pp. 409-13.
Vancouver Yılmaz Z, Güvey H, Çelik S, Soyer Çalışkan C. Effect of complete blood count parameters on the clinical course of COVID-19 in pregnant women. J. Exp. Clin. Med. 2022;39(2):409-13.