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The efficacy of computed tomography-guided percutaneous microwave ablation in patients with osteoid osteoma according to nidus location in long bones: A single-centre initial experience

Year 2022, Volume: 39 Issue: 3, 699 - 705, 30.08.2022

Abstract

This study aims to evaluate the safety and efficacy of microwave ablation (MWA) in the treatment of painful extra-articular osteoid osteoma (OO) in long bones in a consecutive series of patients and to compare the technical and clinical success in terms of pain scores according to their location. A total of 23 patients who were diagnosed with OO in long bones and treated with MWA between January 1, 2016, and June 1, 2020 were enrolled in this study. Medical records and imaging were reviewed for age, gender, size of the radiolucent nidus and duration of pain. Patients were then categorized into three groups according to the location of nidus (pertrochanteric, metaphyseal or diaphyseal). Operation length and technical and clinical success rates were compared. The number and severity of complications were also documented. Technical success was achieved in 100% of patients. Primary clinical success following MWA was 82.6%. The most common location was the pertrochanteric region (34.8%). In comparing the pain scores with the locations of the lesions, no statistically significant difference was found between the first-day (p = 0.504) and first-week (p = 0.648). However, significant difference was present between the first month (p = 0.016), third month (p < 0.001) and sixth month (p = 0.001). The statistically significant differences between the sites were due to the difference between the pertrochanteric and diaphyseal lesions. CT-guided percutaneous MWA is safe and effective in the treatment of OO located in long bones without any recurrence. However, management of pertrochanteric OOs requires specific expertise and follow up. Further studies are expected in the future to assess the long-term efficacy and safety of MWA for the treatment of OO, especially for cases in pertrochanteric locations of the femur, which have an increased risk of local recurrence.

References

  • References Campanacci M, Ruggieri P, Gasbarrini A, Ferraro A, Campanacci L. Osteoid osteoma. Direct visual identification and intralesional excision of the nidus with minimal removal of bone. J Bone Joint Surg Br. 1999;81(5):814-20.
  • Miyazaki, M., Arai, Y., Myoui, A., Gobara, H., Sone, M., Rosenthal et al Phase I/II Multi-Institutional Study of Percutaneous Radiofrequency Ablation for Painful Osteoid Osteoma (JIVROSG-0704). Cardiovasc Intervent Radiol. 2016;39(10):1464-1470.
  • Noordin S, Allana S, Hilal K, Nadeem, N., Lakdawala, R., Sadruddin, A.et al. Osteoid osteoma: contemporary management. Orthop Rev (Pavia) 2018; 10(3): 7496.
  • Hage AN, Chick JFB, Gemmete JJ, Grove JJ, Srinivasa RN. Percutaneous Radiofrequency Ablation for the Treatment of Osteoid Osteoma in Children and Adults: A Comparative Analysis in 92 Patients. Cardiovasc Intervent Radiol. 2018 Sep;41(9):1384-1390.
  • Lorenc T, Kocoń H, Gołębiowski M. Computed tomography-guided percutaneous radiofrequency and laser ablation for the treatment of osteoid osteoma - long-term follow-up from 5 to 10 years. Pol J Radiol. 2021 Jan 12;86:e19-e30.
  • Prud'homme C, Nueffer JP, Runge M, Dubut J, Kastler B, Aubry S. Prospective pilot study of CT-guided microwave ablation in the treatment of osteoid osteomas. Skeletal Radiol. 2017 Mar;46(3):315-323.
  • Basile, A., Failla, G., Reforgiato, A., Scavone, G., Mundo, E., Messina, M., et al. The use of microwaves ablation in the treatment of epiphyseal osteoid osteomas. Cardiovasc Intervent Radiol. 2014;37:737–42.
  • Westlake B, Mazzi J, Tedesco N. Osteoid Osteoma Treatment with Microwave Ablation: A Report of Two Cases. Medicina (Kaunas). 2021;57(5):470.
  • Kostrzewa M, Henzler T, Schoenberg SO, Diehl SJ, Rathmann N. Clinical and Quantitative MRI Perfusion Analysis of Osteoid Osteomas Before and After Microwave Ablation. Anticancer Res. 2019 Jun;39(6):3053-3057.
  • Perry BC, Monroe EJ, McKay T, Kanal KM, Shivaram G. Pediatric Percutaneous Osteoid Osteoma Ablation: Cone-Beam CT with Fluoroscopic Overlay Versus Conventional CT Guidance. Cardiovasc Intervent Radiol. 2017 Oct;40(10):1593-1599.
  • Garge, S., Keshava, S. N., Moses, V., Koshy, G., Ahmed, M., Mammen, S., et al. Radiofrequency Ablation of Osteoid Osteoma in Common and Technically Challenging Locations in Pediatric Population. Indian J Med Paediatr Oncol. 2017;38(3):302-305.
  • Sampath SC, Sampath SC, Rosenthal DI. Serially recurrent osteoid osteoma. Skeletal Radiol. 2015;44(6):875-881.
  • Earhart J, Wellman D, Donaldson J, Chesterton J, King E, Janicki JA. Radiofrequency ablation in the treatment of osteoid osteoma: results and complications. Pediatr Radiol. 2013 Jul;43(7):814-9.
  • Song MH, Yoo WJ, Cho TJ, Chung CY, Park MS, Cheon JE, Choi IH. Clinical and radiological features and skeletal sequelae in childhood intra-/juxta-articular versus extra-articular osteoid osteoma. BMC Musculoskelet Disord. 2015 Jan 31;16(1):3.
  • Kawaguchi Y, Sato C, Hasegawa T, Oka S, Kuwahara H, Norimatsu H. Intraarticular osteoid osteoma associated with synovitis: a possible role of cyclooxygenase-2 expression by osteoblasts in the nidus. Mod Pathol. 2000 Oct;13(10):1086-91.
  • Germann T, Weber MA, Lehner B, Kintzele L, Burkholder I, Kauczor HU, Rehnitz C. Intraarticular Osteoid Osteoma: MRI Characteristics and Clinical Presentation Before and After Radiofrequency Ablation Compared to Extraarticular Osteoid Osteoma. Rofo. 2020 Dec;192(12):1190-1199. English, German.
  • Sacks D, McClenny TE, Cardella JF, Lewis CA. Society of Interventional Radiology clinical practice guidelines. J Vasc Interv Radiol. 2003;14(9 Pt 2):S199-S202.
  • Kulkarni, S. S., Shetty, N. S., Polnaya, A. M., Janu, A., Kumar, S., Puri, A., et al. CT-guided radiofrequency ablation in osteoid osteoma: Result from a tertiary cancer centre in India. Indian J Radiol Imaging. 2017;27(3):318-323.
  • Knudsen M, Riishede A, Lucke A, Gelineck J, Keller J, Baad-Hansen T: Computed tomography-guided radiofrequency ablation is a safe and effective treatment of osteoid osteoma located outside the spine. Dan Med J. 2015, 62:1-5.
  • Cantwell CP, Obyrne J, Eustace S. Current trends in treatment of osteoid osteoma with an emphasis on radiofrequency ablation. Eur Radiol 2004;14:607-17.
  • Lee EH, Shafi M, Hui JH. Osteoid osteoma: a current review. J Pediatr Orthop 2006;26:695-700.
  • Lindquester WS, Crowley J, Hawkins CM. Percutaneous thermal ablation for treatment of osteoid osteoma: a systematic review and analysis. Skeletal Radiol. 2020 Sep;49(9):1403-1411.
  • Vanderschueren GM, Taminiau AH, Obermann WR, van den Berg-Huysmans AA, Bloem JL. Osteoid osteoma: factors for increased risk of unsuccessful thermal coagulation. Radiology. 2004;233(3):757-762.
  • Lanza E, Thouvenin Y, Viala P, Sconfienza LM, Poretti D, Cornalba G, et al. Osteoid osteoma treated by percutaneous thermal ablation: when do we fail? A systematic review and guidelines for future reporting. Cardiovasc Intervent Radiol 2014;37:1530-9.
  • Lubner MG, Brace CL, Hinshaw JL, Lee FT Jr. Microwave tumor ablation: mechanism of action, clinical results, and devices. J Vasc Interv Radiol. 2010;21(8 Suppl):S192-S203.
  • Rinzler ES, Shivaram GM, Shaw DW, Monroe EJ, Koo KSH. Microwave ablation of osteoid osteoma: initial experience and efficacy. Pediatr Radiol. 2019 Apr;49(4):566-570.
  • Yu Y, Sun X, Song X, Tian Z, Zhou Y. A novel surgical approach for the treatment of tumors in the lesser trochanter. Exp Ther Med. 2015 Jul;10(1):201-206.
  • Rehnitz C, Sprengel SD, Lehner B, Ludwig K, Omlor G, Merle C,. et al. CT-guided radiofrequency ablation of osteoid osteoma: correlation of clinical outcome and imaging features. Diagn Interv Radiol. 2013 Jul-Aug;19(4):330-9.
  • Rosenthal DI, Hornicek FJ, Torriani M, Gebhardt MC, Mankin HJ. Osteoid osteoma: percutaneous treatment with radiofrequency energy. Radiology. 2003;229(1):171-175.
  • Becce, F., Theumann, N., Rochette, A., Larousserie, F., Campagna, R., Cherix, S., et al. Osteoid osteoma and osteoid osteoma-mimicking lesions: biopsy findings, distinctive MDCT features and treatment by radiofrequency ablation. Eur Radiol. 2010;20(10):2439-2446.
Year 2022, Volume: 39 Issue: 3, 699 - 705, 30.08.2022

Abstract

References

  • References Campanacci M, Ruggieri P, Gasbarrini A, Ferraro A, Campanacci L. Osteoid osteoma. Direct visual identification and intralesional excision of the nidus with minimal removal of bone. J Bone Joint Surg Br. 1999;81(5):814-20.
  • Miyazaki, M., Arai, Y., Myoui, A., Gobara, H., Sone, M., Rosenthal et al Phase I/II Multi-Institutional Study of Percutaneous Radiofrequency Ablation for Painful Osteoid Osteoma (JIVROSG-0704). Cardiovasc Intervent Radiol. 2016;39(10):1464-1470.
  • Noordin S, Allana S, Hilal K, Nadeem, N., Lakdawala, R., Sadruddin, A.et al. Osteoid osteoma: contemporary management. Orthop Rev (Pavia) 2018; 10(3): 7496.
  • Hage AN, Chick JFB, Gemmete JJ, Grove JJ, Srinivasa RN. Percutaneous Radiofrequency Ablation for the Treatment of Osteoid Osteoma in Children and Adults: A Comparative Analysis in 92 Patients. Cardiovasc Intervent Radiol. 2018 Sep;41(9):1384-1390.
  • Lorenc T, Kocoń H, Gołębiowski M. Computed tomography-guided percutaneous radiofrequency and laser ablation for the treatment of osteoid osteoma - long-term follow-up from 5 to 10 years. Pol J Radiol. 2021 Jan 12;86:e19-e30.
  • Prud'homme C, Nueffer JP, Runge M, Dubut J, Kastler B, Aubry S. Prospective pilot study of CT-guided microwave ablation in the treatment of osteoid osteomas. Skeletal Radiol. 2017 Mar;46(3):315-323.
  • Basile, A., Failla, G., Reforgiato, A., Scavone, G., Mundo, E., Messina, M., et al. The use of microwaves ablation in the treatment of epiphyseal osteoid osteomas. Cardiovasc Intervent Radiol. 2014;37:737–42.
  • Westlake B, Mazzi J, Tedesco N. Osteoid Osteoma Treatment with Microwave Ablation: A Report of Two Cases. Medicina (Kaunas). 2021;57(5):470.
  • Kostrzewa M, Henzler T, Schoenberg SO, Diehl SJ, Rathmann N. Clinical and Quantitative MRI Perfusion Analysis of Osteoid Osteomas Before and After Microwave Ablation. Anticancer Res. 2019 Jun;39(6):3053-3057.
  • Perry BC, Monroe EJ, McKay T, Kanal KM, Shivaram G. Pediatric Percutaneous Osteoid Osteoma Ablation: Cone-Beam CT with Fluoroscopic Overlay Versus Conventional CT Guidance. Cardiovasc Intervent Radiol. 2017 Oct;40(10):1593-1599.
  • Garge, S., Keshava, S. N., Moses, V., Koshy, G., Ahmed, M., Mammen, S., et al. Radiofrequency Ablation of Osteoid Osteoma in Common and Technically Challenging Locations in Pediatric Population. Indian J Med Paediatr Oncol. 2017;38(3):302-305.
  • Sampath SC, Sampath SC, Rosenthal DI. Serially recurrent osteoid osteoma. Skeletal Radiol. 2015;44(6):875-881.
  • Earhart J, Wellman D, Donaldson J, Chesterton J, King E, Janicki JA. Radiofrequency ablation in the treatment of osteoid osteoma: results and complications. Pediatr Radiol. 2013 Jul;43(7):814-9.
  • Song MH, Yoo WJ, Cho TJ, Chung CY, Park MS, Cheon JE, Choi IH. Clinical and radiological features and skeletal sequelae in childhood intra-/juxta-articular versus extra-articular osteoid osteoma. BMC Musculoskelet Disord. 2015 Jan 31;16(1):3.
  • Kawaguchi Y, Sato C, Hasegawa T, Oka S, Kuwahara H, Norimatsu H. Intraarticular osteoid osteoma associated with synovitis: a possible role of cyclooxygenase-2 expression by osteoblasts in the nidus. Mod Pathol. 2000 Oct;13(10):1086-91.
  • Germann T, Weber MA, Lehner B, Kintzele L, Burkholder I, Kauczor HU, Rehnitz C. Intraarticular Osteoid Osteoma: MRI Characteristics and Clinical Presentation Before and After Radiofrequency Ablation Compared to Extraarticular Osteoid Osteoma. Rofo. 2020 Dec;192(12):1190-1199. English, German.
  • Sacks D, McClenny TE, Cardella JF, Lewis CA. Society of Interventional Radiology clinical practice guidelines. J Vasc Interv Radiol. 2003;14(9 Pt 2):S199-S202.
  • Kulkarni, S. S., Shetty, N. S., Polnaya, A. M., Janu, A., Kumar, S., Puri, A., et al. CT-guided radiofrequency ablation in osteoid osteoma: Result from a tertiary cancer centre in India. Indian J Radiol Imaging. 2017;27(3):318-323.
  • Knudsen M, Riishede A, Lucke A, Gelineck J, Keller J, Baad-Hansen T: Computed tomography-guided radiofrequency ablation is a safe and effective treatment of osteoid osteoma located outside the spine. Dan Med J. 2015, 62:1-5.
  • Cantwell CP, Obyrne J, Eustace S. Current trends in treatment of osteoid osteoma with an emphasis on radiofrequency ablation. Eur Radiol 2004;14:607-17.
  • Lee EH, Shafi M, Hui JH. Osteoid osteoma: a current review. J Pediatr Orthop 2006;26:695-700.
  • Lindquester WS, Crowley J, Hawkins CM. Percutaneous thermal ablation for treatment of osteoid osteoma: a systematic review and analysis. Skeletal Radiol. 2020 Sep;49(9):1403-1411.
  • Vanderschueren GM, Taminiau AH, Obermann WR, van den Berg-Huysmans AA, Bloem JL. Osteoid osteoma: factors for increased risk of unsuccessful thermal coagulation. Radiology. 2004;233(3):757-762.
  • Lanza E, Thouvenin Y, Viala P, Sconfienza LM, Poretti D, Cornalba G, et al. Osteoid osteoma treated by percutaneous thermal ablation: when do we fail? A systematic review and guidelines for future reporting. Cardiovasc Intervent Radiol 2014;37:1530-9.
  • Lubner MG, Brace CL, Hinshaw JL, Lee FT Jr. Microwave tumor ablation: mechanism of action, clinical results, and devices. J Vasc Interv Radiol. 2010;21(8 Suppl):S192-S203.
  • Rinzler ES, Shivaram GM, Shaw DW, Monroe EJ, Koo KSH. Microwave ablation of osteoid osteoma: initial experience and efficacy. Pediatr Radiol. 2019 Apr;49(4):566-570.
  • Yu Y, Sun X, Song X, Tian Z, Zhou Y. A novel surgical approach for the treatment of tumors in the lesser trochanter. Exp Ther Med. 2015 Jul;10(1):201-206.
  • Rehnitz C, Sprengel SD, Lehner B, Ludwig K, Omlor G, Merle C,. et al. CT-guided radiofrequency ablation of osteoid osteoma: correlation of clinical outcome and imaging features. Diagn Interv Radiol. 2013 Jul-Aug;19(4):330-9.
  • Rosenthal DI, Hornicek FJ, Torriani M, Gebhardt MC, Mankin HJ. Osteoid osteoma: percutaneous treatment with radiofrequency energy. Radiology. 2003;229(1):171-175.
  • Becce, F., Theumann, N., Rochette, A., Larousserie, F., Campagna, R., Cherix, S., et al. Osteoid osteoma and osteoid osteoma-mimicking lesions: biopsy findings, distinctive MDCT features and treatment by radiofrequency ablation. Eur Radiol. 2010;20(10):2439-2446.
There are 30 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Clinical Research
Authors

Aysu Başak Özbalcı 0000-0001-9974-5974

Nevzat Dabak 0000-0002-4591-7897

Early Pub Date August 30, 2022
Publication Date August 30, 2022
Submission Date January 19, 2022
Acceptance Date February 15, 2022
Published in Issue Year 2022 Volume: 39 Issue: 3

Cite

APA Özbalcı, A. B., & Dabak, N. (2022). The efficacy of computed tomography-guided percutaneous microwave ablation in patients with osteoid osteoma according to nidus location in long bones: A single-centre initial experience. Journal of Experimental and Clinical Medicine, 39(3), 699-705.
AMA Özbalcı AB, Dabak N. The efficacy of computed tomography-guided percutaneous microwave ablation in patients with osteoid osteoma according to nidus location in long bones: A single-centre initial experience. J. Exp. Clin. Med. August 2022;39(3):699-705.
Chicago Özbalcı, Aysu Başak, and Nevzat Dabak. “The Efficacy of Computed Tomography-Guided Percutaneous Microwave Ablation in Patients With Osteoid Osteoma According to Nidus Location in Long Bones: A Single-Centre Initial Experience”. Journal of Experimental and Clinical Medicine 39, no. 3 (August 2022): 699-705.
EndNote Özbalcı AB, Dabak N (August 1, 2022) The efficacy of computed tomography-guided percutaneous microwave ablation in patients with osteoid osteoma according to nidus location in long bones: A single-centre initial experience. Journal of Experimental and Clinical Medicine 39 3 699–705.
IEEE A. B. Özbalcı and N. Dabak, “The efficacy of computed tomography-guided percutaneous microwave ablation in patients with osteoid osteoma according to nidus location in long bones: A single-centre initial experience”, J. Exp. Clin. Med., vol. 39, no. 3, pp. 699–705, 2022.
ISNAD Özbalcı, Aysu Başak - Dabak, Nevzat. “The Efficacy of Computed Tomography-Guided Percutaneous Microwave Ablation in Patients With Osteoid Osteoma According to Nidus Location in Long Bones: A Single-Centre Initial Experience”. Journal of Experimental and Clinical Medicine 39/3 (August 2022), 699-705.
JAMA Özbalcı AB, Dabak N. The efficacy of computed tomography-guided percutaneous microwave ablation in patients with osteoid osteoma according to nidus location in long bones: A single-centre initial experience. J. Exp. Clin. Med. 2022;39:699–705.
MLA Özbalcı, Aysu Başak and Nevzat Dabak. “The Efficacy of Computed Tomography-Guided Percutaneous Microwave Ablation in Patients With Osteoid Osteoma According to Nidus Location in Long Bones: A Single-Centre Initial Experience”. Journal of Experimental and Clinical Medicine, vol. 39, no. 3, 2022, pp. 699-05.
Vancouver Özbalcı AB, Dabak N. The efficacy of computed tomography-guided percutaneous microwave ablation in patients with osteoid osteoma according to nidus location in long bones: A single-centre initial experience. J. Exp. Clin. Med. 2022;39(3):699-705.