Morphometric examination of vertebrae prominens with computed tomography images

Year 2024, Volume: 41 Issue: 2, 264 - 270, 19.05.2024

Mustafa Furkan Öztürk , Meltem Açar Güdek , Murat Beyhan

Abstract

The seventh cervical vertebra, also known as the vertebra prominens, possesses a distinctive structure with the most prominent spinous process among the cervical vertebrae. This study aims to assess the morphometric properties of the vertebra prominens concerning gender and age. In a retrospective analysis, computed tomography (CT) images from 200 individuals (100 females, 100 males), aged 18 to 75, devoid of cervical pathologies, were utilized. These images were sourced from the Picture Archiving and Communication System (PACS) archive of the Department of Radiology at Tokat Gaziosmanpaşa University. Participants were divided into two age groups: 18-30 years and 31-74 years. Measurements were obtained from 1.25 mm thick CT images using the Sectra program. Statistically significant differences in spinal dimensions were observed based on gender (p<0.001). Typically, males exhibited larger spinal dimensions compared to females, indicating a gender-based influence on spinal morphology. Age-wise analysis revealed significant gender-based disparities (p<0.001), illustrating age-gender variations. The antero-posterior length of the vertebra body showed gender-related differences in median values (p<0.001), with males having a median value of 15 mm and females 12.7 mm. Gender-based distinctions in the width of the right pediculus vertebral arch (p<0.001) were observed, with median values of 7.16 mm for males and 6.23 mm for females. Similarly, the left pediculus vertebral arch width displayed gender-related discrepancies in median values (p<0.001). Significant sex-related variations in spinal dimensions were noted (p<0.001), with males having larger vertebrae compared to females, indicating the impact of gender on spinal morphology. Age-related analysis also revealed significant gender-based differences (p<0.001), underscoring age-gender variations. These findings highlight the importance of considering both gender and age when assessing spinal morphometry. Understanding these variations contributes to a comprehensive comprehension understanding of spinal anatomy, potentially informing clinical interventions and treatment strategies tailored to individual characteristics.

Keywords

vertebrae prominens, computed tomography, morphometry, cervical

Ethical Statement

Etik kurulumuzun 16.03.2023 tarihli toplantısında görüşülen 23-KAEK-069 kayıt numaralı 'Bilgisayarlı Tomografi Görüntüleri Üzerinden Veterba Prominensin Morfometrik Olarak İncelenmesi' başlıklı çalışmanız gerekçe, amaç, yaklaşım ve yöntemleri dikkate alınarak incelenmiş ve uygun bulunmuş olup, çalışmanın başvuru dosyasında belirtilen merkezde gerçekleştirilmesinde etik ve bilimsel sakınca bulunmadığına kara verilmiştir.

Supporting Institution

Tokat Gaziosmanpaşa Üniversitesi Tıp Fakültesi

Project Number

23-KAEK-069

References

• Ozan, H., 2014. Ozan Anatomi. Klinisyen Tıp Kitapevi, 32-41, Ankara.
• Raveendranath V, Kavitha T, Umamageswari A. Morphometry of the Uncinate Process, Vertebral Body, and Lamina of the C3-7 Vertebrae Relevant to Cervical Spine Surgery. Neurospine. 2019;16(4):748-55. Epub 2019/07/10. doi: 10.14245/ns.1836272.136. PubMed PMID: 31284340; PubMed Central PMCID: PMCPmc6944996.
• Mahiphot J, Iamsaard S, Sawatpanich T, Sae-Jung S, Khamanarong K. A Morphometric Study on Subaxial Cervical Pedicles of Thai People. Spine. 2019;44(10):E579-e84. Epub 2018/11/06. doi: 10.1097/brs.0000000000002920. PubMed PMID: 30395094.
• Gilliam TB, Freedson PS, Geenen DL, Shahraray B. Physical activity patterns determined by heart rate monitoring in 6-7 year-old children. Medicine and science in sports and exercise. 1981;13(1):65-7. Epub 1981/01/01. PubMed PMID: 7219138.
• Taylor JR, Twomey LT, Corker M. Bone and soft tissue injuries in post-mortem lumbar spines. Paraplegia. 1990;28(2):119-29. Epub 1990/02/01. doi: 10.1038/sc.1990.14. PubMed PMID: 2235021.
• Gilsanz V, Boechat MI, Gilsanz R, Loro ML, Roe TF, Goodman WG. Gender differences in vertebral sizes in adults: biomechanical implications. Radiology. 1994;190(3):678-82. Epub 1994/03/01. doi: 10.1148/radiology.190.3.8115610. PubMed PMID: 8115610.
• Us AK, Tekdemir İ, Elhan A, Yazar T. LUMBAL VERTEBRALARIN MORFOMETRİK İNCELEMESİ. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1994;47(3). doi: 10.1501/Tipfak_0000000337.
• Yu CC, Bajwa NS, Toy JO, Ahn UM, Ahn NU. Pedicle morphometry of upper thoracic vertebrae: an anatomic study of 503 cadaveric specimens. Spine. 2014;39(20):E1201-9. Epub 2014/07/02. doi: 10.1097/brs.0000000000000505. PubMed PMID: 24983934.
• Prabavathy G, Chandra Philip X, Arthi G, Sadeesh T. Morphometric study of cervical vertebrae C3-C7 in South Indian population –A clinico-anatomical approach. Italian Journal of Anatomy and Embryology. 2017;122(1):49-57.
• Mahto AK, Omar S. Clinico-anatomical approach for instrumentation of the cervical spine: A morphometric study on typical cervical vertebrae. International Journal of Scientific Study. 2015;3(4):143-5.
• Desdicioğlu K, Erdoğan K, Çizmeci G, Malas MA. Vertebralara Ait Anatomik Yapıların Morfometrik Olarak İncelenmesi ve Klinik Açıdan Değerlendirilmesi: Anatomik Çalışma. SDÜ Sağlık Bilimleri Dergisi. 2017:1-. doi: 10.22312/sdusbed.224963.
• EphraimVikramRao. K, Rao BS, Vinila BHS. MORPHOMETRIC ANALYSIS OF TYPICAL CERVICAL VERTEBRAE AND THEIR CLINICAL IMPLICATIONS: A CROSS SECTIONAL STUDY. International Journal of Approximate Reasoning. 2016;4:2988-92.
• Yilmazlar S, Kocaeli H, Uz A, Tekdemir I. Clinical importance of ligamentous and osseous structures in the cervical uncovertebral foraminal region. Clinical anatomy (New York, NY). 2003;16(5):404-10. Epub 2003/08/07. doi: 10.1002/ca.10158. PubMed PMID: 12903062.
• Abuzayed B, Tutunculer B, Kucukyuruk B, Tuzgen S. Anatomic basis of anterior and posterior instrumentation of the spine: morphometric study. Surgical and radiologic anatomy : SRA. 2010;32(1):75-85. Epub 2009/08/22. doi: 10.1007/s00276-009-0545-4. PubMed PMID: 19696959.
• Cruz JJBC, Larios AGL, Sánchez AGS, Silva EEVS, Gauna SEVG, Sanchez Uresti A, et al. Morphometric Study of Cervical Vertebrae C3-C7 in a Population from Northeastern Mexico. International Journal of Morphology. 2011;29:325-30.
• Matveeva N, Janevski P, Nakeva N, Zhivadinovik J, Dodevski A. Morphometric analysis of the cervical spinal canal on MRI. Prilozi (Makedonska akademija na naukite i umetnostite Oddelenie za medicinski nauki). 2013;34(2):97-103. Epub 2013/11/28. PubMed PMID: 24280784.
• Acar M, Alkan BS, Tolu I, Seckin E, Soyal R, Saricat S, et al. Morphometric analysis of cervical vertebrae with multidetector computerized tomography. Annals of Medical Research. 2021;26(9):1986-90.
• Kumar S, Saini NK, Singh D, Chadha M, Mehrotra G. Computed tomographic analysis of cervical spine pedicles in the adult Indian population. Surgical neurology international. 2021;12:68. Epub 2021/03/27. doi: 10.25259/sni_926_2020. PubMed PMID: 33767872; PubMed Central PMCID: PMCPmc7982095.
• Rao RD, Marawar SV, Stemper BD, Yoganandan N, Shender BS. Computerized tomographic morphometric analysis of subaxial cervical spine pedicles in young asymptomatic volunteers. The Journal of bone and joint surgery American volume. 2008;90(9):1914-21. Epub 2008/09/03. doi: 10.2106/jbjs.g.01166. PubMed PMID: 18762652.
• Munusamy T, Thien A, Anthony MG, Bakthavachalam R, Dinesh SK. Computed tomographic morphometric analysis of cervical pedicles in a multi-ethnic Asian population and relevance to subaxial cervical pedicle screw fixation. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2015;24(1):120-6. Epub 2014/08/27. doi: 10.1007/s00586-014-3526-1. PubMed PMID: 25155836.
• Herrero CF, Luis do Nascimento A, Maranho DAC, Ferreira-Filho NM, Nogueira CP, Nogueira-Barbosa MH, et al. Cervical pedicle morphometry in a Latin American population: A Brazilian study. Medicine. 2016;95(25):e3947. Epub 2016/06/24. doi: 10.1097/md.0000000000003947. PubMed PMID: 27336889; PubMed Central PMCID: PMCPmc4998327.