Yara İyileşmesinde Yeni Bir Yaklaşım Olarak Gümüş Nanopartiküller: Antibakteriyel Etkinliğe Odaklanma

Yıl 2025, Cilt: 3 Sayı: 1, 6 - 12, 31.01.2025

Berfin Rumeysa Sarı , Çiğdem Aydın Acar

Öz

Nanoteknoloji, nano ölçekte gelişmiş işlevsel malzemeler geliştirmek için biyoloji, kimya, malzeme bilimi ve fizik gibi farklı bilimsel disiplinlerdeki araştırmacıları bir araya getiren çok disiplinli bir alandır. Nanoteknoloji tabanlı çözümler, özellikle nanopartiküller, mevcut terapi ve teşhis yöntemleriyle karşılaştırıldığında hem etkinlik hem de güvenlik açısından önemli avantajlar sağlayabildikleri için tıbbi araştırmalarda giderek daha yaygın hale gelmektedir. Son yıllarda yapılan çalışmalar ile gümüş nanopartiküller, Escherichia coli, Bacillus subtilis, Vibria cholera, Pseudomonas aeruginosa, Syphillis typhus ve Staphylococcus aureus gibi bulaşıcı organizmalara karşı oldukça güçlü antimikrobiyal ajanlar olduğu gösterilmiştir. Gümüş nanopartiküllerin bu denli geniş antibakteriyal aktivesi gümüşün tıp alanında, gümüş nanopartiküllerın ise biyomedikal alanın çeşitli alanlarında kullanımını etkilemiştir. AgNP'li biyomedikal ürünler tipik olarak yara iyileşmesini hızlandırarak ve enfekte olmuş hücrelerin hızlı parçalanması yoluyla bakterileri inhibe ederek bakteriyel enfeksiyonları önlemek için kullanılmaktadır.
Bu çalışmada gümüş nanopartiküllerin antibakteriyal mekanizması ve yara iyileştirmedeki etkisi üzerinde durulmuştur.

Anahtar Kelimeler

Antibakteriyel, Gümüş nanopartikül, Nanoteknoloji, Yara iyileşmesi

Etik Beyan

Not applicable

Destekleyen Kurum

This research did not receive any specific grant from funding agencies in the public, commercial, or not-forprofit sectors.

Silver Nanoparticles as a New Approach to Wound Healing: Focus on Antibacterial Efficacy

Öz

Nanotechnology is a multidisciplinary field that brings together researchers from various scientific disciplines, including biology, chemistry, materials science, and physics, to develop advanced functional materials on a nanoscale. Nanotechnology-based solutions, particularly nanoparticles, are becoming increasingly prevalent in medical research due to their significant advantages in both efficacy and safety compared to conventional therapies and diagnostic methods. Recent studies have shown that silver nanoparticles are highly potent antimicrobial agents against infectious organisms such as Escherichia coli, Bacillus subtilis, Vibrio cholera, Pseudomonas aeruginosa, Syphillis typhus, and Staphylococcus aureus. This broad antibacterial activity of silver nanoparticles has influenced the use of silver in medicine and expanded the applications of silver nanoparticles across various fields of biomedicine. Biomedical products containing AgNPs are typically used to accelerate wound healing and prevent bacterial infections by inhibiting bacteria through the rapid breakdown of infected cells.
This study focuses on the antibacterial mechanism of silver nanoparticles and their effect on wound healing.

Anahtar Kelimeler

Antibacterial, Silver nanoparticles, Nanotechnology, Wound healing

Kaynakça

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