Gebelerde toksoplazma antikor seroprevalansı: Tarama yapalım mı?

Year 2019, , 415 - 421, 01.12.2019

Hakan Çökmez , Çetin Aydın

https://doi.org/10.21601/ortadogutipdergisi.510487

Abstract

Amaç: Bizim bu çalışmadaki amacımız, kurumumuza prenatal takip için başvurmuş ve toksoplazma için serolojik testler uygulanmış gebelerde seroprevalans değerini ortaya koyarak, prenatal takipte toksoplazma taramasının güncel yerini belirlemektir.
Gereç ve Yöntemler: Bu retrospektif çalışmaya 15-49 yaş aralığında olup, prenatal takip amacıyla kliniğimize başvurmuş ve Toxoplasma gondii (t.gondii) serolojik testleri uygulanmış gebeler alındı. Olguların yaş, doğum yerleri, ve anti-t.gondii immunglobulin (Ig) M ve G verileri hastane kayıtları taranarak elde edildi. Olgular doğum yerlerine göre gruplandırıldı ve toksoplazma seropozitivitesi açısından karşılaştırılarak analiz edildi.
Bulgular: Çalışmaya alınan 817 gebenin 296’sında (%36,2) anti-t.gondii IgG pozitifti. Anti-t.gondii IgG seropozitivitesi bakımından Ege Bölgesi kökenli hasta grubu (%30,1) ile Güneydoğu Anadolu kökenli hasta grubu (%47,1) arasında anlamlı fark vardı (p<0,05). Ayrıca toksoplazma seroprevalansı Türkiye’ nin batısından kökenli hasta grubunda (%29,5) Suriyeli hasta grubuna göre (%45,7) anlamlı derecede düşüktü (p<0,05).
Sonuçlar: Türkiye’nin batısında, doğuya kıyasla düşük toksoplazma seroprevalansı ile ilişkili yüksek toksoplazma enfeksiyonu duyarlılığı nedeniyle, konjenital toksoplazmoz riskini önleme amaçlı, en azından bölge tabanlı prenatal toksoplazma taraması yapılmalıdır.

Keywords

toksoplazmozis, doğumsal, seroepidemiyolojik çalışmalar

Seroprevalence of toxoplasma antibody in pregnant women: Should we screen?

Abstract

Aim: Our aim in this study was to determine the current location of toxoplasma screening in prenatal follow-up by presenting seroprevalence in pregnant women who applied for prenatal follow-up and applied serological tests for toxoplasma.
Material and Methods: This retrospective study was conducted between the ages of 15-49 and pregnant women who applied to our clinic for prenatal follow-up and who underwent Toxoplasma gondii (t.gondii) serological tests. Age, place of birth, and anti-t.gondii immunoglobulin (Ig) M and G data were obtained by screening hospital records. Cases were grouped according to their place of birth and analyzed for toxoplasma seropositivity.
Results: Of the 817 pregnant women included in the study, 296 (36.2%) had anti-t.gondii IgG positive. In terms of seropositivity of anti-t.gondii IgG, there was a significant difference between the patients of Aegean Region (30.1%) and patients of Southeast Anatolia (47.1%) (p <0.05). Also toxoplasmosis seroprevalence Turkey’s west of the origin of the patient group (29.5%) compared to the Syrians patients (45.7%) was significantly lower (p <0.05).
Conclusion: In west of Turkey, due to the high sensitivity of toxoplasma infection associated with lower toxoplasma seroprevalence compared to the east, intended to prevent the risk of congenital toxoplasmosis can be increased we recommend at least region-based prenatal toxoplasma scanning.

Keywords

toxoplasma, toxoplasmosis, congenital, seroepidomiologic studies

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