TEN case due to allopurinol in chronic kidney disease

Year 2018, Volume: 10 Issue: 2, 213 - 215, 01.06.2018

Ahu Cerit , Tayfun Arslan Okan Çalışkan , Ayşe Önal Aydın Çifci

https://doi.org/10.21601/ortadogutipdergisi.312753

Abstract

Toxic epidermal necrolysis, Stevens-Johnson syndrome are the
most important factors in the etiology of many conditions, especially
antibiotics. These clinical tables can often interfere with each other, which
can lead to delayed diagnosis. We present toxic epidermal necrolysis due to the
use of allopurinol. Since we have provided a center with a burning unit at a rapid
rate and started treatment earlier in this center, we have received a complete
recovery and we are pleased to offer this kind of treatment to take attention
to the importance of early diagnosis and treatment.

Keywords

TEN, allopurinol, chronic kidney disease

Kronik böbrek hastasında allopurinol kullanımına bağlı TEN olgusu

Abstract

Toksik
epidermal nekroliz, Stevens-Johnson sendromu gibi pek çok durumun etiyolojisinde en önemli faktör başta antibiyotikler olmak üzere
ilaçlardır. Bu
klinik tablolar birbirleriyle sıklıkla karışabilir bu da tanıda gecikmelere yol
açabilir. Olgumuzda allopürinol  kullanımına bağlı toksik epidermal nekroliz
düşündük. Yanık ünitesi olan bir merkeze hızlıca sevkini
sağlayıp bu merkezdeki tedavisine daha erken başlandığı için tam bir iyileşme
ile netice aldığımızdan, bu tür hastalarda erken tanı-tedavinin önemine dikkat
çekmek için sunulmaya değer gördük.için tam bir iyileşme
ile netice aldığımızdan, bu tür hastalarda erken tanı-tedavinin önemine dikkat
çekmek için sunulmaya değer gördük.

 

Keywords

TEN, allopürinol, kronik böbrek hastalığı

References

• 1. Fritsch PO, Ruiz-Meldonado R. Stevens-Johnson syndrome-toxic epidermal necrolysis. In- Freedberg IM, Eisen A7 Wolff K (eds)Fitzpatrick's Dermatology in General Medicine. 5th ed, New York. Mc Graw-Hill, 1999: 644-54.
• 2.Jonzzo JL. Blood vessel-based inflammatory disorders In Moschella SL, Hurley HJ (eds). Dermatology. 3rd ed, Philadelphia WB Saunders 1992:577-93.
• 3. Bastuji-Garin S, Rzany B, Stern RS, et al Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme. Arch Dermatol 1993:129 92-6.
• 4. Assier H, Bastuji-Gann S; Revuz J, Reujeau JC Erythema multiforme with mucous membrane involvement and Stevens-Johnson syndrome are clinically different disorders with distinct causes. Arch Dermatol 1995,131:539-43.
• 5. Roujeau JC: Drug-induced toxic epidermal necrolysis. II. Current aspects. Clin Dermatol 1993;11:493-500.
• 6. Roujeau JC, Kelly JP, Naldi L et al: Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. N Engl J Med 1995;333:1600-7.
• 7. Mockenhaupt M, Messenheimer J, Tennis P et al: Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepilectics. Neurology 2005;64:1134-8.
• 8. Akman A, Alpsoy E: Eritema Multiforme, Steven-Johnson Sendromu ve Toksik Epidermal Nekroliz (Lyell Sendromu). Türkiye Klinikleri J Surg Med Sci 2006;2:6-15.
• 9. Ghislain PD, Roujeau JC: Treatment of severe drug reactions: Stevens-Johnson syndrome, toxic epidermal necrolysis and hypersensitivity syndrome. Dermatol Online J 2002;8:5.
• 10. McGee T, Munster A: Toxic epidermal necrolysis syndrome: mortality rate reduced with early referral to regional bum center. Plast Reconstr Surg 1998;102:1018-22.
• 11. Kelemen JJ III, Cioffi WG, McManus WF, Mason AD Jr, Pruitt BA Jr: Bum center care for patients with toxic epidermal necrolysis. J Am Coll Surg 1995;180:273-8.
• 12. Revuz J, Penso D, Roujeau J-C, et al: Toxic epidermal necrolysis:clinical findings and prognosis factors in 87 patients. Arch Dermatol 1987;123:1160-5.