Amputasyon güdüğünde Citrobacter freundii’ye bağlı postoperatif osteomyelit gelişen olgu

Year 2018, Volume: 10 Issue: 3, 400 - 402, 30.09.2018

Esra Yüksekkaya Salih Cesur Çiğdem Ataman Hatipoğlu, Şükran Baysal Esra Kaya Kılıç Sami Kınıklı

https://doi.org/10.21601/ortadogutipdergisi.335495

Cited By: 1

Abstract

Gram negatif basillere bağlı
olarak osteomyelit gelişimi nadiren bildirilmektedir; özellikle orak hücreli
anemi, intravenöz ilaç bağımlılığı gibi altta yatan hastalığı olan olgularda
görülmektedir. Citrobacter freundii, Enterobacteriaceae ailesinde yer alan
Gram negatif bir basil olup, üriner sistem infeksiyonu, pnömoni, bakteriyemi, sepsis,
intraabdominal enfeksiyonları ve santral sinir sistemi enfeksiyonlarına neden
olabilmektedir; nadiren osteomyelite neden olabilir.

Bu yazıda, silahlı yaralanma sonrası ampütasyon
uygulanan, amputasyon bölgesinde C. freundii’ye
bağlı olarak postoperatif osteomyelit gelişen, 38 yaşında bir erkek hasta
sunulmuştur.   

Keywords

Osteomyelit, postoperatif, Citrobacter freundii

Postoperative osteomyelitis case due to Citrobacter freundii in amputation stump

Abstract

Osteomyelitis due to Gram negative bacilli is rarely
reported, it can be seen especially in patients with underlying diseases as sickle
cell anemia or intravenous drug abuse. Citrobacter
freundii is a Gram-negative bacilli in the Enterobacteriaceae family and it may cause urinary tract infections,
pneumonia, bacteremia, sepsis, intraabdominal infections and central nervous
system infections, but rarely osteomyelitis.

In this article, we present a 38 year old male patient
who underwent amputation after a gunshot injury and developed postoperative osteomyelitis
on amputation region due to C. freundii.

Keywords

Osteomyelitis, postoperative, Citrobacter freundii

References

• 1. Mansour Rezaei, Alisha Akya, Azam Elahi, Keyghobad Ghadiri, Somayeh Jafari. The clonal relationship among the Citrobacter freundii isolated from the main hospital in Kermanshah, west of Iran. Iran J Microbiol 2016;8:175-80.
• 2. Whalen JG, Mully TW, English JC. 3rd Spontaneous Citrobacter freundii infection in an immunocompetent patient. Arch Dermatol 2007; 143:124-5.
• 3. Gupta R, Rauf SJ, Singh S, Smith J, Agraharkar ML. Sepsis in a renal transplant recipient due to Citrobacter braakii. South Med J 2003;96:796-8.
• 4. Liu LH, Wang NY, Wu AY, Lin CC, Lee CM, Liu CP. Citrobacter freundii bacteremia: Risk factors of mortality and prevalence of resistance genes. J Microbiol Immunol Infect 2017;1684-1182.30059-2.
• 5. Iredell J, Brown J, Tagg K. Antibiotic resistance in Enterobacteriaceae: mechanisms and clinical implications. BMJ 2016; 352:h6420.
• 6. Cantón R, Oliver A, Coque TM, Varela Mdel C, Pérez-Díaz JC, Baquero F. Epidemiology of extended-spectrum beta-lactamase-producing Enterobacter isolates in a Spanish hospital during a 12-year period. J Clin Microbiol 2002;40:1237-43.
• 7. Chuang YM, Tseng SP, Teng LJ, Ho YC, Hsueh PR. Emergence of cefotaxime resistance in Citrobacter freundii causing necrotizing fasciitis and osteomyelitis. J Infect. 2006 Sep;53:161-3.
• 8. Stricker T, Fröhlich S, Nadal D. Osteomyelitis and septic arthritis due to Citrobacter freundii and Haemophilus influenzae type b. J Paediatr Child Health 1998;34:90-1.
• 9. De Bernardi B, Garventa A, Garrè ML, Taccone A, Canale G, Gandus S. 2 cases of osteomyelitis in acute leukemia in the induction phase of treatment. Pediatr Med Chir 1983;5:205-9.
• 10. Zimmerli W, Sendi P. Orthopaedic biofilm infections. APMIS. 2017;125:353-64.
• 11. Peng J, Ren Y, He W, et al. Epidemiological, clinical and microbiological characteristics of patients with post-traumatic osteomyelitis of limb fractures in southwest China: A hospital-based study. J Bone Jt Infect 2017;2:149-53.
• 12. Aragón-Sánchez J, Lipsky BA, Lázaro-Martínez JL. Gram-negative diabetic foot osteomyelitis: risk factors and clinical presentation. Int J Low Extrem Wounds 2013 Mar;12:63-8.
• 13. De A, Raj HJ, Maiti PK. Biofilm in Osteomyelitis caused by a rare pathogen, Morganella morganii: A case report. J Clin Diagn Res 2016;10:DD06-8.
• 14. Berbari EF, Steckelberg JM, Osmon DR. Osteomyelitis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015;106:1318-27.