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Benign vokal kord patolojisi nedeniyle opere edilen hastaların retrospektif incelenmesi

Year 2019, Volume: 11 Issue: 2, 187 - 192, 01.06.2019
https://doi.org/10.21601/ortadogutipdergisi.405520

Abstract

Amaç: Kliniğimizde opere olan benign vokal kord
lezyonları hastaların patolojik ve klinik verilerinin sunulması ve dağılım yüzdelerinin
değerlendirilmesi amaçlanmıştır.



Gereç ve Yöntem: Çalışma Kırıkkale Üniversitesi Tıp Fakültesi
Kulak Burun Boğaz Anabilim Dalında Aralık 2013 - Mart 2017 tarihleri arasında benign
vokal kord lezyonları tanısı alan hasta dosyalarının retrospektif olarak değerlendirilmesi
ile gerçekleştirilmiştir.



Bulgular: Ortalama yaşları 47,8 olan toplam 108 hastanın
verileri incelendi. Hastaların 24’ü (%22,3) kadın 84’ü (%77,7) erkek idi. Hastaların
patoloji sonuçları 61 (%56,4) vokal kord polipi, 20 (%18,5) değişik derecelerde
keratotik lezyon olan lökoplazi, 11 (%10,1) Reinke ödemi, 7 (%6,4) larengeal kist,
6 (%5,5) vokal kord nodülü, 2 (%1,8) larinks papillomatozu ve 1 (%0,9) larengosel
olarak kaydedildi. Hastaların 76’sının (%70,3) anamnezinde sigara öyküsü olduğu
gözlendi.



Sonuç: Benign vokal kord lezyonları bulunan hastaların
patoloji sonuçlarında en sık vokal kord polipi ile karşılaşılmaktadır. Her kliniğin
benign vokal kord lezyonları patoloji sonuçlarının değerlendirilmesi ile ülkemizdeki
benign vokal kord lezyonları sonuçlarının dağılımı ile ilgili veriler oluşturulabilir.

References

  • Zeitels SM, Healy GB. Laryngology and phonosurgery. N Engl J Med. 2003;28;349(9):882-92.
  • Friedrich G, Remacle M, Birchall M, Marie JP, Arens C. Defining phonosurgery: aproposal for classification and nomenclature by the Phonosurgery Committee of the European Laryngological Society (ELS). Eur Arch Otorhinolaryngol. 2007;264(10):1191-200.
  • Bykova VP, Kochesokova EA, Ivanchenko GF, Rotova ID. The morphology of vocal fold polyps and mucosa in Reinke’s edema. Arkh Patol. 2015; 77(1):30-7.
  • Effat KG, Milad M. A comparative histopathological study of vocal fold polyps in smokers versus non-smokers. J Laryngol Otol. 2015; 129(5):484-8.
  • Zhang Y, Liang G, Sun N, ve ark. Comparison of CO2 laser and conventional laryngomicrosurgery treatments of polyp and leukoplakia of the vocal fold. Int J ClinExp Med. 2015;8(10):18265-74.
  • Byeon HK, Han JH, Choi BI, Hwang HJ, Kim JH, Choi HS. Treatment of Hemorrhagic Vocal Polyps by Pulsed Dye Laser-Assisted Laryngomicrosurgery. Biomed Res Int. 2015;2015:820654.
  • Jensen JB, Rasmussen N. Phonosurgery of vocal fold polyps, cysts and nodules is beneficial. Dan Med J. 2013; 60(2):A4577.
  • Zhukhovitskaya A, Battaglia D, Khosla SM, Murry T, Sulica L. Gender and age in benign vocal fold lesions. Laryngoscope. 2015; 125(1):191-6.
  • Fang TJ, Lin WN, Lee LY, ve ark. Classification of vocal fold leukoplakia by clinical scoring. Head Neck. 2016; 38 Suppl 1:E1998-2003.
  • Eckel HE, Raunik W, Rogatsch H. Laryngeal intraepithelial neoplasia. Laryngorhinootologie. 2008; 87(6):425-38.
  • Ahn A, Wang L, Slaughter JC, Nguyen AM, Ossoff RH, Francis DO. Serial full-thickness excision of dysplastic vocal fold leukoplakia: Diagnostic or therapeutic?. Laryngoscope. 2016; 126(4):923-7.
  • Kunieda C, Kanazawa T, Komazawa D, ve ark. The Correlation between the Size of Vocal Polyps, Vocal Nodules and Vocal Dysfunction, before and after Laryngeal Microsurgery. Nihon Jibiinkoka Gakkai Kaiho. 2015; 118(10):1212-9.
  • Ju YH, Jung KY, Kwon SY, ve ark. Effect of voice therapy after phonomicrosurgery for vocal polyps: a prospective, historically controlled, clinical study. J Laryngol Otol. 2013; 127(11):1134-8.
  • Ruiz R, Achlatis S, Sridharan S, ve ark. The effect of antireflux therapy on phonomicrosurgical outcomes: a preliminary retrospective study. J Voice. 2014;28(2):241-4.
  • Yang SW, Chao WC, Lee YS, ve ark. Treatment outcome of vocal cord leukoplakia by transoral laser microsurgery. Lasers Med Sci. 2017; 32(1):19-27.
  • Byeon H. Relationships among smoking, organic, and functional voice disorders in Korean general population. J Voice. 2015; 29(3):312-6.
  • Narwani V, Harries M. Treatment modality: a predictor of continued tobacco use after treatment in patients with laryngeal cancer. J Laryngol Otol. 2014; 128(2):153-8.
  • Mallis A, Jelastopulu E, Mastronikolis NS, Naxakis SS, Kourousis C, Papadas TA. Laryngeal cancer and passive smoking: the neglected factor? Eur Arch Otorhinolaryngol. 2011; 268(5):727-31.
  • Melinceanu L, Sarafoleanu C, Lerescu L, Tucureanu C, Caraş I, Sălăgeanu A. Impact of smoking on the immunological profile of patients with laryngeal carcinoma. J Med Life. 2009; 2(2):211-8.
  • Simo R, Bradley P, Chevalier D, ve ark. European Laryngological Society: ELS recommendations for the follow-up of patients treated for laryngeal cancer. Eur Arch Otorhinolaryngol. 2014; 271(9):2469-79.
  • Nicholson AG, Perry LJ, Cury PM, Jackson P, McCormick CM, Corrin B, ve ark. Reproducibility of the WHO/IASLC grading system for pre-invasive squamous lesions of the bronchus: a study of inter-observer and intra-observer variation. Histopathology. 2001; 38(3):202-8.
  • Branski RC, Saltman B, Sulica L, ve ark. Cigarette smoke and reactive oxygen species metabolism: implications for the pathophysiology of Reinke’s edema. Laryngoscope. 2009; 119(10):2014-8.
  • Martins RH, Tavares EL, Pessin AB. Are Vocal Alterations Caused by Smoking in Reinke’s Edema in Women Entirely Reversible After Microsurgery and Smoking Cessation? J Voice. 2016; 21. pii: S0892-1997(16)30115-1.
  • Wang J, Fang R, Peterson A, Jiang JJ. The Protective Role of Autophagy in Human Vocal Fold Fibroblasts under Cigarette Smoke Extract Exposure: A New Insight into the Study of Reinke’s Edema. ORL J Otorhinolaryngol Relat Spec. 2016;78(1):26-35.
  • Martins RH, do Amaral HA, Tavares EL, Martins MG, Gonçalves TM, Dias NH. Voice Disorders: Etiology and Diagnosis. J Voice. 2016; 30(6):761.e1-761.e9.
  • Hantzakos A, Remacle M, Dikkers FG, ve ark. Exudative lesions of Reinke’s space: a terminology proposal. Eur Arch Otorhinolaryngol. 2009; 266(6):869-78.
  • Nielsen VM, Højslet PE, Karlsmose M. Surgical treatment of Reinke’s oedema (long-term results) J Laryngol Otol. 1986;100:187–190.
  • Hirano M. Endolaryngeal microsurgery. In: English GM, editor. Otolaryngology. Vol 3. Philadelphia, PA: Lippincott; 1988. pp. 1–11.
  • Koszewski IJ, Hoffman MR, Young WG, Lai YT, Dailey SH. Office-Based Photoangiolytic Laser Treatment of Reinke’s Edema: Safety and Voice Outcomes. Otolaryngol Head Neck Surg. 2015; 152(6):1075-81.
  • DeSanto LW, Devine KD, Weiland LH. Cysts of the larynx--Classification. Laryngoscope. 2015; 125(12):2629.
  • Won SJ, Kim RB, Kim JP, Park JJ, Kwon MS, Woo SH. The prevalence and factors associate with vocal nodules in general population: Cross-sectional epidemiological study. Medicine (Baltimore). 2016; 95(39):e4971.
  • Mattei A, Revis J, Giovanni A. Personality traits inventory in patients with vocal nodules. Eur Arch Otorhinolaryngol. 2017; 274(4):1911-7.
  • Godínez JM, Nicolás-Párraga S, Pimenoff VN, ve ark. Phylogenetically related, clinically different: human papillomaviruses 6 and 11 variants distribution in genital warts and in laryngeal papillomatosis. Clin Microbiol Infect. 2014; 20(6):O406-13.
  • Papaspyrou G, Schick B, Papaspyrou S, Eivazi B, Al Kadah B. Retrospective analysis of laser vs other therapeutic modalities for laryngeal papillomatosis: European multicenter study. J BUON. 2016; 21(5):1274-8.
  • Imaizumi M, Okano W, Tada Y, Omori K. Surgical treatment of laryngeal papillomatosis using narrow band imaging. Otolaryngol Head Neck Surg. 2012;147(3):522-4.
  • Venkatesan NN, Pine HS, Underbrink MP. Recurrent respiratory papillomatosis. Otolaryngol Clin North Am. 2012; 45(3):671-94, viii-ix.

Retrospective analysis of patients who were operated with a benign vocal cord pathology

Year 2019, Volume: 11 Issue: 2, 187 - 192, 01.06.2019
https://doi.org/10.21601/ortadogutipdergisi.405520

Abstract

Aim: We aimed to evaluate the presentation and distribution
of pathologic and clinical data of patients who were operated with benign vocal
cord lesions in our clinic.



Material and Method: The study was performed with retrospective
evaluation of patient files diagnosed as benign vocal cord lesions between December
2013 and March 2017 at Kırıkkale University Medical Faculty Otorhinolaryngology
Department.



Results: Their average age was 47.8 a total of 108
patients were analyzed. Twenty four patients (22.3%) were female and 84 patients
(77.7%) were male. According to pathological results of patients, 61 patients results
were vocal cord polyp (56.4%), 20 patients results were leukoplakia (18.5%), 11
patients were Reinke’s edema (10.1%), 7 patients were laryngeal cyst (6.4%), 6 patients
were vocal cord nodule (5.5%), 2 patients were laryngeal papillomatosis (1.8%),
1 patient was laryngocele (0.9%).



Conclusion: Patients with benign vocal cord lesions are
most frequently encountered with vocal cord polyp in pathology results. With the
evaluation of pathological results of benign vocal cord lesions of each clinic,
data on the distribution of the results of benign vocal cord lesions in our country
can be created.

References

  • Zeitels SM, Healy GB. Laryngology and phonosurgery. N Engl J Med. 2003;28;349(9):882-92.
  • Friedrich G, Remacle M, Birchall M, Marie JP, Arens C. Defining phonosurgery: aproposal for classification and nomenclature by the Phonosurgery Committee of the European Laryngological Society (ELS). Eur Arch Otorhinolaryngol. 2007;264(10):1191-200.
  • Bykova VP, Kochesokova EA, Ivanchenko GF, Rotova ID. The morphology of vocal fold polyps and mucosa in Reinke’s edema. Arkh Patol. 2015; 77(1):30-7.
  • Effat KG, Milad M. A comparative histopathological study of vocal fold polyps in smokers versus non-smokers. J Laryngol Otol. 2015; 129(5):484-8.
  • Zhang Y, Liang G, Sun N, ve ark. Comparison of CO2 laser and conventional laryngomicrosurgery treatments of polyp and leukoplakia of the vocal fold. Int J ClinExp Med. 2015;8(10):18265-74.
  • Byeon HK, Han JH, Choi BI, Hwang HJ, Kim JH, Choi HS. Treatment of Hemorrhagic Vocal Polyps by Pulsed Dye Laser-Assisted Laryngomicrosurgery. Biomed Res Int. 2015;2015:820654.
  • Jensen JB, Rasmussen N. Phonosurgery of vocal fold polyps, cysts and nodules is beneficial. Dan Med J. 2013; 60(2):A4577.
  • Zhukhovitskaya A, Battaglia D, Khosla SM, Murry T, Sulica L. Gender and age in benign vocal fold lesions. Laryngoscope. 2015; 125(1):191-6.
  • Fang TJ, Lin WN, Lee LY, ve ark. Classification of vocal fold leukoplakia by clinical scoring. Head Neck. 2016; 38 Suppl 1:E1998-2003.
  • Eckel HE, Raunik W, Rogatsch H. Laryngeal intraepithelial neoplasia. Laryngorhinootologie. 2008; 87(6):425-38.
  • Ahn A, Wang L, Slaughter JC, Nguyen AM, Ossoff RH, Francis DO. Serial full-thickness excision of dysplastic vocal fold leukoplakia: Diagnostic or therapeutic?. Laryngoscope. 2016; 126(4):923-7.
  • Kunieda C, Kanazawa T, Komazawa D, ve ark. The Correlation between the Size of Vocal Polyps, Vocal Nodules and Vocal Dysfunction, before and after Laryngeal Microsurgery. Nihon Jibiinkoka Gakkai Kaiho. 2015; 118(10):1212-9.
  • Ju YH, Jung KY, Kwon SY, ve ark. Effect of voice therapy after phonomicrosurgery for vocal polyps: a prospective, historically controlled, clinical study. J Laryngol Otol. 2013; 127(11):1134-8.
  • Ruiz R, Achlatis S, Sridharan S, ve ark. The effect of antireflux therapy on phonomicrosurgical outcomes: a preliminary retrospective study. J Voice. 2014;28(2):241-4.
  • Yang SW, Chao WC, Lee YS, ve ark. Treatment outcome of vocal cord leukoplakia by transoral laser microsurgery. Lasers Med Sci. 2017; 32(1):19-27.
  • Byeon H. Relationships among smoking, organic, and functional voice disorders in Korean general population. J Voice. 2015; 29(3):312-6.
  • Narwani V, Harries M. Treatment modality: a predictor of continued tobacco use after treatment in patients with laryngeal cancer. J Laryngol Otol. 2014; 128(2):153-8.
  • Mallis A, Jelastopulu E, Mastronikolis NS, Naxakis SS, Kourousis C, Papadas TA. Laryngeal cancer and passive smoking: the neglected factor? Eur Arch Otorhinolaryngol. 2011; 268(5):727-31.
  • Melinceanu L, Sarafoleanu C, Lerescu L, Tucureanu C, Caraş I, Sălăgeanu A. Impact of smoking on the immunological profile of patients with laryngeal carcinoma. J Med Life. 2009; 2(2):211-8.
  • Simo R, Bradley P, Chevalier D, ve ark. European Laryngological Society: ELS recommendations for the follow-up of patients treated for laryngeal cancer. Eur Arch Otorhinolaryngol. 2014; 271(9):2469-79.
  • Nicholson AG, Perry LJ, Cury PM, Jackson P, McCormick CM, Corrin B, ve ark. Reproducibility of the WHO/IASLC grading system for pre-invasive squamous lesions of the bronchus: a study of inter-observer and intra-observer variation. Histopathology. 2001; 38(3):202-8.
  • Branski RC, Saltman B, Sulica L, ve ark. Cigarette smoke and reactive oxygen species metabolism: implications for the pathophysiology of Reinke’s edema. Laryngoscope. 2009; 119(10):2014-8.
  • Martins RH, Tavares EL, Pessin AB. Are Vocal Alterations Caused by Smoking in Reinke’s Edema in Women Entirely Reversible After Microsurgery and Smoking Cessation? J Voice. 2016; 21. pii: S0892-1997(16)30115-1.
  • Wang J, Fang R, Peterson A, Jiang JJ. The Protective Role of Autophagy in Human Vocal Fold Fibroblasts under Cigarette Smoke Extract Exposure: A New Insight into the Study of Reinke’s Edema. ORL J Otorhinolaryngol Relat Spec. 2016;78(1):26-35.
  • Martins RH, do Amaral HA, Tavares EL, Martins MG, Gonçalves TM, Dias NH. Voice Disorders: Etiology and Diagnosis. J Voice. 2016; 30(6):761.e1-761.e9.
  • Hantzakos A, Remacle M, Dikkers FG, ve ark. Exudative lesions of Reinke’s space: a terminology proposal. Eur Arch Otorhinolaryngol. 2009; 266(6):869-78.
  • Nielsen VM, Højslet PE, Karlsmose M. Surgical treatment of Reinke’s oedema (long-term results) J Laryngol Otol. 1986;100:187–190.
  • Hirano M. Endolaryngeal microsurgery. In: English GM, editor. Otolaryngology. Vol 3. Philadelphia, PA: Lippincott; 1988. pp. 1–11.
  • Koszewski IJ, Hoffman MR, Young WG, Lai YT, Dailey SH. Office-Based Photoangiolytic Laser Treatment of Reinke’s Edema: Safety and Voice Outcomes. Otolaryngol Head Neck Surg. 2015; 152(6):1075-81.
  • DeSanto LW, Devine KD, Weiland LH. Cysts of the larynx--Classification. Laryngoscope. 2015; 125(12):2629.
  • Won SJ, Kim RB, Kim JP, Park JJ, Kwon MS, Woo SH. The prevalence and factors associate with vocal nodules in general population: Cross-sectional epidemiological study. Medicine (Baltimore). 2016; 95(39):e4971.
  • Mattei A, Revis J, Giovanni A. Personality traits inventory in patients with vocal nodules. Eur Arch Otorhinolaryngol. 2017; 274(4):1911-7.
  • Godínez JM, Nicolás-Párraga S, Pimenoff VN, ve ark. Phylogenetically related, clinically different: human papillomaviruses 6 and 11 variants distribution in genital warts and in laryngeal papillomatosis. Clin Microbiol Infect. 2014; 20(6):O406-13.
  • Papaspyrou G, Schick B, Papaspyrou S, Eivazi B, Al Kadah B. Retrospective analysis of laser vs other therapeutic modalities for laryngeal papillomatosis: European multicenter study. J BUON. 2016; 21(5):1274-8.
  • Imaizumi M, Okano W, Tada Y, Omori K. Surgical treatment of laryngeal papillomatosis using narrow band imaging. Otolaryngol Head Neck Surg. 2012;147(3):522-4.
  • Venkatesan NN, Pine HS, Underbrink MP. Recurrent respiratory papillomatosis. Otolaryngol Clin North Am. 2012; 45(3):671-94, viii-ix.
There are 36 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Original article
Authors

Burak Mustafa Taş 0000-0002-1983-5329

Gökçe Şimşek 0000-0001-5281-0986

Mahi Balcı 0000-0001-5836-2344

Rahmi Kılıç 0000-0001-7946-9706

Publication Date June 1, 2019
Published in Issue Year 2019 Volume: 11 Issue: 2

Cite

Vancouver Taş BM, Şimşek G, Balcı M, Kılıç R. Benign vokal kord patolojisi nedeniyle opere edilen hastaların retrospektif incelenmesi. omj. 2019;11(2):187-92.

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