Year 2020, Volume 12 , Issue 2, Pages 295 - 298 2020-06-01

Yaşlı bir kadın hastada duloksetin kullanımına bağlı hiponatremi
Hyponatremia due to duloxetine use in an elderly woman patient

Buket CİNEMRE [1] , Ali ERDOĞAN [2] , Burak KULAKSIZOĞLU [3] , Mert Sinan BİNGÖL [4]


Hiponatremi, antidepresanların potansiyel olarak tehlikeli bir yan etkisidir. Hemen hemen her antidepresan hiponatremiye neden olabilir. Duloksetin kaynaklı hiponatremi genellikle yaşlı kadınlarda görülen bir yan etkidir. İleri yaş ve kadın cinsiyetine ek olarak; düşük vücut ağırlığı, komorbid hastalıkların varlığı hiponatremi gelişimi için diğer önemli risk faktörleridir. Bu olgu sunumunda, ilacın kesilmesinden hemen sonra düzelen duloksetin tedavisi ile hiponatremi gelişen depresif bozukluğu olan bir hasta sunulmaktadır. Bizim olgumuzda, duloksetin kesilmesine ek olarak, hiponatreminin destekleyici elektrolit tedavisi ile çözülmesi bize geriatrik popülasyonlarda antidepresan tedavisinden önce ve sonra sodyum seviyelerinin izlenmesinin önemini hatırlatmaktadır.
Hyponatremia is a potentially dangerous side effect of antidepressants. Almost every antidepressant can cause hyponatremia. Duloxetine-induced hyponatremia is a side effect that is usually seen in older women. In addition to advanced age and female sex; low body weight, presence of comorbid diseases are other important risk factors for the development of hyponatremia. In this case report we present a patient with depressive disorder who developed hyponatremia with duloxetine treatment which resolved immediately after the cessation of the medication with supportive electrolyte treatment. In our case, the resolution of hyponatremia with supportive electrolyte treatment in addition to the cessation of duloxetine reminds us about the importance of monitoring sodium levels both before and after antidepressant treatment in geriatric populations.
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Primary Language en
Subjects Health Care Sciences and Services
Journal Section Case report
Authors

Orcid: 0000-0001-6480-1454
Author: Buket CİNEMRE
Institution: Department of Psychiatry, Akdeniz University Medical Faculty, 07070 Antalya, Turkey
Country: Turkey


Orcid: 0000-0003-0329-6778
Author: Ali ERDOĞAN (Primary Author)
Institution: Department of Psychiatry, Akdeniz University Medical Faculty, 07070 Antalya, Turkey
Country: Turkey


Orcid: 0000-0002-6566-5850
Author: Burak KULAKSIZOĞLU
Institution: Department of Psychiatry, Akdeniz University Medical Faculty, 07070 Antalya, Turkey
Country: Turkey


Orcid: 0000-0002-6566-5850
Author: Mert Sinan BİNGÖL
Institution: Department of Psychiatry, Akdeniz University Medical Faculty, 07070 Antalya, Turkey
Country: Turkey


Dates

Publication Date : June 1, 2020

Vancouver Cinemre B , Erdoğan A , Kulaksızoğlu B , Bingöl M . Hyponatremia due to duloxetine use in an elderly woman patient. Ortadoğu Tıp Dergisi. 2020; 12(2): 295-298.