Sağlık Çalışanlarında ve Poliklinik Hastalarında H1N1 IgG Antikor Sıklığının Karşılaştırılması

Year 2016, Volume: 8 Issue: 1, 7 - 11, 01.03.2016

Salih Cesur Hasan Irmak Aydın Çifci Sami Kınıklı Ali Pekcan Demiröz Zeynep Bıyıklı Gençtürk

Abstract

Amaç: Pandemik influenza döneminde sağlık çalışanlarında H1N1 influenza virüsü IgG antikor sıklığının H1N1 döneminde üst solunum yolu semptomları ile müracat eden ve olası pandemik H1N1 enfeksiyonu olan poliklinik hastaları ile karşılaştırılması idi.Gereç ve Yöntemler: Çalışmaya 53 sağlık personeli [ 15 doktor , 16 hemşire , 22 yardımcı sağlık personeli ile 29 poliklinik hastası olmak üzere influenza A H1N1 aşısı uygulanmamış 82 kişi dahil edildi. Sağlık çalışanlarında ve poliklinik hastalarında influenzaya yönelik semptomların varlığı sorgulandı. Sağlık personeli ve hasta grubunda H1N1 IgG antikor düzeyleri ELISA yöntemiyle belirlendi. İstatistiksel analizler SPSS programında yapıldı. p

Keywords

Sağlık çalışanları, poliklinik hastaları, H1N1, seroprevalans, IgG, ELISA

Evaluation of The Seroprevalence of H1N1 IgG Antibodies Between Healthcare Workers and Outpatients

Abstract

Aim: The aim of the present study was to compare the seroprevalence of pandemic H1N1 IgG antibodies between health care workers and patients presenting with upper airway symptoms suggestive of H1N1 influenza infection who are admitted to the outpatient clinics during pandemic H1N1 influenza infection.Material and Methods: The present study comprised 82 subjects unvaccinated with influenza A H1N1 vaccination, including 53 health care workers 33 females, 20 males, 15 doctors; median age: 38 years , 16 nurses median age: 26.5 years , 22 auxiliary health care workers median age: 32 years , and 29 outpatients 14 females, 15 males; median age: 38 years . The presence of symptoms suggestive of pandemic influenza infection was questioned in the health care providers and outpatients. Serum H1N1 IgG antibody levels were determined in the health care workers and outpatients using the ELISA method. The statistical analyses were performed using the SPSS software package. ANOVA analysis of variance was used to evaluate the significance of difference between the groups, and the Kruskal-Wallis test was used to evaluate the significance of difference in terms of median values. The nominal variables were analyzed using Pearson’s chi-square test or Fisher’s exact test. A p value of < 0.05 was considered statistically significant. Results: The seroprevalence of H1N1 IgG antibody positivity for health care workers and outpatients were %43.3 and %6.9, respectively. H1N1 IgG antibody seropositivity did not show a significant relation with gender and mean age p=0.87 and p=0.657, respectively . There was a statistically significant difference between health care workers and outpatients in terms of H1N1 IgG antibody seropositivity p

Keywords

Healht care workers, outpatients, H1N1, seroprevalance, IgG, ELISA

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