Mide Kanserinde Tanı Anındaki Evre ile Patolojik Alt Tip ve Lokalizasyonun İlişkisi

Year 2015, Volume: 7 Issue: 4, 178 - 182, 01.12.2015

Gökşen İnanç İmamoğlu Mustafa Altınbaş Süleyman Şahin Fatih Karataş Ebru Sarı Doğan Yazılıtaş Semiha Urvay Uğur Ersoy İlhan Hacıbekiroğlu Ramazan Esen Tülay Eren Dilşen Çolak

Abstract

Amaç: Bu çalışmadaki amacımız tanı anındaki mide kanserli hastalarda evre ile patolojik alt tip ve tümör lokalizasyonunun ilişkisinin araştırılması. Yöntem ve Gereçler: Ocak 2008 ve ekim 2011 tarihleri arasında mide kanseri nedeniyle ameliyat olan 90 hasta retrospektif olarak incelendi. Kanserin Lauren sınıflamasına göre patolojik tiplemesi yapıldı. Hastalığın tanı anındaki evresi ile yaş, cinsiyet, lokalizasyon ve patolojik tipi arasında istatistiksel olarak anlamlı bir ilişkinin olup olmadığı araştırıldı.Bulgular: Hastaların yaş ortalaması 61,1 ± 13,5’di . Doksan hastanın 71’i erkek, 19’u ise kadındı. Kırkdokuz hastada intestinal %54.4 , 40 hastada diffüz tip 44.5 hastalık bulundu. Hastalığı kardiya ve fundusta lokalize olanlar daha yaşlı grubunda iken, antrum lokalizasyonunun daha genç yaş grubu ile ilişkili olduğu bulundu. Fakat, her iki patolojik tip arasında belirgin bir yaş farkı olmadığı görüldü. Kardiya, fundus ve korpus ağırlıklı olarak ileri evrelerle ilişkili iken, antrum ise sıklıkla evre IIIB ve daha erken evrelerle ilişkili bulundu. İntestinal tipin difüz tipe göre daha düşük evrelerde olduğu görüldü p

Keywords

Mide kanseri, lokalizasyon, patolojik alt tip, evre

The Relation Between Stage at Diagnosis and Pathological Subtype and Tumor Localization in Gastric Cancer

Abstract

Aim:Our aim in this study is to investigate the relation between disease stage and tumor localisation and pathological subtypes at diagnosis in gastric cancer patients. Material and Methods: Ninety patients who underwent surgery due to gastric cancer between January 2008 and October 2011 were retrospectively analysed. Pathological typing was performed according to the Lauren classification. The relation between disease stage and age, gender, tumor location and pathological subtype were investigated whether there is a statistically significance.Results: The mean age of patients’ was 61.1 ± 13.5 . Of these 90 patients included into this study, 71 were male and 19 were female. Intestinal type disease was found in 49 patients and diffuse type was in 40. While patients whose disease localised in cardia and fundus were in older age group, antrum localisation was found to be associated with younger age group. However, no significant difference in age was found between two pathological subtype. Tumor localisation in cardia, fundus and corpus were predominantly associated with advanced stages, although the antrum localisation was found to be associated with stage IIIB or earlier stages. Intestinal type was observed in lower stages compared to diffuse type p < 0.001 . While intestinal type of cancer was mainly observed in antrum and corpus, both pathologic types were found at similar rates in cardia.Discussion: As a result, intestinal type of gastric cancer is detected at an earlier stage when compared to diffuse type. Tumors localised in the antrum were mostly intestinal type and were determined at earlier stages compared to proximal tumors

Keywords

Gastric cancer, localisation, pathological subtype, stage

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