Volume: 3 Issue: 2, 5/27/23

Year: 2023

Pharmata is a scientific, open access, online-only periodical published in accordance with independent, unbiased, and double-blinded peer-review principles. The journal is an official publication of the Atatürk University, and published quarterly in January, April, July, and October. The publication language of the journal is English.

Pharmata aims to contribute to the literature by publishing manuscripts at the highest scientific level. The journal publishes research articles, reviews and short communications that are prepared in accordance with ethical guidelines.

The scope of the journal includes but not limited to pharmaceutical analysis of complex system, quality control and methods of biotech drugs, action mechanism and their metabolisms in body, quantitative and qualitative analysis in the drug screening process, molecular pharmacology, biopharmaceutics, pharmacognosy, pharmaceutical botany, pharmaceutical technology studies, clinical laboratory and bioanalysis, the pharmacological studies, the toxicologic studies, analytical chemistry techniques and methods, new biochemistry methods for pharmaceutical analysis, rapid screening methods, new analytical techniques and methods, pharmaceutical chemistry, synthesis and analysis new drug molecules, others: pharmaceutical solid materials (including biomaterials, polymers and nanoparticles) biotechnology products (including genes, peptides, proteins and vaccines) engineered cells.

The target audience of the journal includes researchers and specialists who are interested or working in all fields in the journal’s scope.

The editorial and publication processes of the journal are shaped in accordance with the guidelines of the International Committee of Medical Journal Editors (ICMJE), World Association of Medical Editors (WAME), Council of Science Editors (CSE), Committee on Publication Ethics (COPE), European Association of Science Editors (EASE), and National Information Standards Organization (NISO). The journal is in conformity with the Principles of Transparency and Best Practice in Scholarly Publishing (doaj.org/bestpractice).

All expenses of the journal are covered by the Atatürk University. Processing and publication are free of charge with the journal. No fees are requested from the authors at any point throughout the evaluation and publication process. All manuscripts must be submitted via the online submission system, which is available at https://www.pharmata-ataunipress.org. The journal guidelines, technical information, and the required forms are available on the journal’s web page.

Disclaimer
Statements or opinions expressed in the manuscripts published in the journal reflect the views of the author(s) and not the opinions of the editors, editorial board, and/or publisher; the editors, editorial board, and publisher disclaim any responsibility or liability for such materials.

Open Access Statement
Pharmata is an open access publication, and the journal’s publication model is based on Budapest Access Initiative (BOAI) declaration. All published content is available online, free of charge at https://www.pharmata-ataunipress.org. Authors retain the copyright of their published work in the Pharmata. The journal’s content is licensed under a Creative Commons Attribution-NonCommercial (CC BY-NC) 4.0 International License which permits third parties to share and adapt the content for non-commercial purposes by giving the appropriate credit to the original work.

From January 2023 onwards, content is licensed under a Creative Commons CC BY-NC 4.0 license. The journal’s back content was published under a traditional copyright license however the archive is available for free access.

Editor in Chief: Yücel KADIOĞLU
Address: Department of Analytical Chemistry, Atatürk University, Faculty of Pharmacy, Erzurum, Turkey
E-mail: yucel@atauni.edu.tr

Publisher: Atatürk University
Address: Atatürk University, Yakutiye, Erzurum, Turkey

Publishing Service: AVES
Address: Büyükdere Cad., 105/9 34394 Şişli, İstanbul, Turkey
Phone: +90 212 217 17 00
E-mail: info@avesyayincilik.com
Webpage: www.avesyayincilik.com

How to Submit a Manuscript?

Copyright Agreement and Acknowledgement of Authorship Form

Pharmata is a scientific, open access, online-only periodical published in accordance with independent, unbiased, and double-blinded peer-review principles. The journal is an official publication of the Atatürk University, and published quarterly in January, April, July, and October. The publication language of the journal is English.

Pharmata aims to contribute to the literature by publishing manuscripts at the highest scientific level. The journal publishes research articles, reviews and short communications that are prepared in accordance with ethical guidelines.

The scope of the journal includes but not limited to pharmaceutical analysis of complex system, quality control and methods of biotech drugs, action mechanism and their metabolisms in body, quantitative and qualitative analysis in the drug screening process, molecular pharmacology, biopharmaceutics, pharmacognosy, pharmaceutical botany, pharmaceutical technology studies, clinical laboratory and bioanalysis, the pharmacological studies, the toxicologic studies, analytical chemistry techniques and methods, new biochemistry methods for pharmaceutical analysis, rapid screening methods, new analytical techniques and methods, pharmaceutical chemistry, synthesis and analysis new drug molecules, others: pharmaceutical solid materials (including biomaterials, polymers and nanoparticles) biotechnology products (including genes, peptides, proteins and vaccines) engineered cells.

The target audience of the journal includes researchers and specialists who are interested or working in all fields in the journal’s scope.

EDITORIAL AND PUBLICATION PROCESS
The editorial and publication processes of the journal are shaped in accordance with the guidelines of the International Council of Medical Journal Editors (ICMJE), the World Association of Medical Editors (WAME), Council of Science Editors (CSE), the Committee on Publication Ethics (COPE), the European Association of Science Editors (EASE), and National Information Standards Organization (NISO). The journal conforms to the Principles of Transparency and Best Practice in Scholarly Publishing (doaj.org/bestpractice).

Originality, high scientific quality, and citation potential are the most important criteria for a manuscript to be accepted for publication. Manuscripts submitted for evaluation should not have been previously presented or already published in an electronic or printed medium. The journal should be informed of manuscripts that have been submitted to another journal for evaluation and rejected for publication. The submission of previous reviewer reports will expedite the evaluation process. Manuscripts that have been presented in a meeting should be submitted with detailed information on the organization, including the name, date, and location of the organization.

PEER REVIEW PROCESS
Manuscripts submitted to the Pharmata will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in their fields in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions.

ETHICAL GUIDELINES
An approval of research protocols by the Ethics Committee in accordance with international agreements (World Medical Association Declaration of Helsinki “Ethical Principles for Medical Research Involving Human Subjects,” amended in October 2013, www.wma.net) is required for experimental, clinical, and drug studies and for some case reports. If required, ethics committee reports, or an equivalent official document will be requested from the authors. Submissions which do not have ethical approval will be reviewed according to COPE’s Research, Audit and Service Evaluations guideline.

Such manuscripts can be rejected after editorial review due to the lack of ethics committee approval.

For studies carried out on animals, an approval of research protocols by the Ethics Committee in accordance with international agreements (Guide for the care and use of laboratory animals, 8th edition, 2011" and/or “International Guiding Principles for Biomedical Research Involving Animals, 2012”) is required. Also, the measures taken to prevent pain and suffering of the animals should be stated clearly in such studies.

Ethics committee information should be written with the date and approval number. Information on patient consent, the name of the ethics committee, and the ethics committee approval number and date should also be stated in the Methods section of the manuscript.

ERRATUM
The correction requests submitted by the authors are reviewed by the Editorial Board and the corrections are applied based on the decision of the Editorial Board. In case of corrections in the published text, the readers are informed by publishing the Erratum text in the number following the correction. The edited article is updated on the journal web page and in the indexes when the journal is scanned.

PLAGIARISM AND ETHICAL MISCONDUCT
Pharmata is extremely sensitive about plagiarism. All submissions are screened by a similarity detection software (iThenticate by CrossCheck) at any point during the peer-review and/or production process.

Even if you are the author of the phrases or sentences, the text should not have unacceptable similarity with the previously published data. When you are discussing others' (or your own) previous work, please make sure that you cite the material correctly in every instance.

Authors are strongly recommended to avoid any form of plagiarism and ethical misconduct that are exemplified below.

Self- plagiarism (text-recycling): Overlapping sections or sentences with the author’s previous publications without citing them. Even if you are the author of the phrases or sentences, the text should not have unacceptable similarity with the previously published data.

Salami slicing: Using the same data of a research into several different articles. Reporting the same hypotheses, population, and methods of a study into different papers is not acceptable.

Data Fabrication: It is the addition of data that never occurred during the gathering of data or the experiments. Results and their interpretation must be based on the complete data sets and reported accordingly.

Data Manipulation/Falsification: It means manipulating research data with the intention of giving a false impression. This includes manipulating images (e.g. micrographs, gels, radiological images), removing outliers or ‘inconvenient’ results, changing data points, etc.

In the event of alleged or suspected research misconduct, e.g., plagiarism, citation manipulation, and data falsification/fabrication, the Editorial Board will follow and act according to COPE flowcharts.

AUTHORSHIP
Each person listed as an author should fulfill the authorship criteria recommended by the International Committee of Medical Journal Editors (ICMJE - www.icmje.org). The ICMJE recommends that authorship is based on the following four criteria:

1. Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; AND
2. Drafting the work or revising it critically for important intellectual content; AND
3. Final approval of the version to be published; AND
4. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

In addition to being accountable for the parts of the work he/she has done, an author should be able to identify which co-authors are responsible for specific other parts of the work. Also, authors should have confidence in the integrity of the contributions of their co-authors.

All those designated as authors should meet all four criteria for authorship, and all who meet the four criteria should be identified as authors. Those who do not meet all four criteria should be acknowledged in the title page of the manuscript.

Pharmata requires corresponding authors to submit a signed and scanned version of the Copyright Agreement and Acknowledgement of Authorship form (available for download https://www.pharmata-ataunipress.org) during the initial submission process to act appropriately on authorship rights and to prevent ghost or honorary authorship. If the editorial board suspects a case of “gift authorship,” the submission will be rejected without further review. As part of the submission of the manuscript, the corresponding author should also send a short statement declaring that he/she accepts to undertake all the responsibility for authorship during the submission and review stages of the manuscript.

CHANGE OF AUTHORSHIP
Pharmata reviews the authorship according to the author’s declaration in the Title Page, thus it is the authors responsibility to send the final order of the complete author names. Requests in the change of authorship (e.g. removal/addition of the authors, change in the order etc) after submission are subject to editorial approval. Editorial Board will investigate this kind of cases and act following COPE flowcharts.

Change of authorship requests should be submitted to the Editorial Office with an official letter stating the reasons for the change. The letter must be signed by all authors and include their approval on the change in authorship. If the request is approved by the Editorial Board, authors need to submit a new Copyright Agreement Form according to the final order list.

DECLARATION OF INTEREST
Pharmata requires and encourages the authors and the individuals involved in the evaluation process of submitted manuscripts to disclose any existing or potential conflicts of interests, including financial, consultant, and institutional, that might lead to potential bias or a conflict of interest. Any financial grants or other support received for a submitted study from individuals or institutions should be disclosed to the Editorial Board. To disclose a potential conflict of interest, the ICMJE Potential Conflict of Interest Disclosure Form should be filled in and submitted by all contributing authors. The journal’s Editorial Board resolves cases of a potential conflict of interest of the editors, authors, or reviewers within the scope of COPE and ICMJE guidelines.

COPYRIGHT AND LICENSE
Pharmata requires each submission to be accompanied by a Copyright Agreement and Acknowledgement of Authorship form (available for download at https://www.pharmata-ataunipress.org/). By signing this form, authors retain the copyright of their work and agree that the article, if accepted for publication by the Pharmata will be licensed under a Creative Commons Attribution-NonCommercial (CC BY-NC) 4.0 International License which permits third parties to share and adapt the content for non-commercial purposes by giving the appropriate credit to the original work.

From January 2023 onwards, content is licensed under a Creative Commons CC BY-NC 4.0 license. The journal’s back content was published under a traditional copyright license however the archive is available for free access.

When using previously published content, including figures, tables, or any other material in both print and electronic formats, authors must obtain permission from the copyright holder. Legal, financial and criminal liabilities in this regard belong to the author(s).

POST-PUBLICATION CORRECTION REQUESTS AND RETRACTIONS
All post-publication correction requests are subjected to editorial decision. Editors review the cases considering journal policies and the highest editorial standards that are adhered to ICMJE and COPE guidelines. If the correction/change is accepted to be implement, the article will be updated with an Erratum or Correction Notice and the journal record will be updated in the related indexes.

In the cases of ethical misconduct concerns, the case will be investigated by the editors according to COPE guidelines. A retraction notice will be issued if the investigation results in the verification of the concern. The paper will remain in the online version of the journal and the retraction notice will be enclosed in the article’s record. The article record will be updated in the related indexes.

WITHDRAWAL REQUESTS
Withdrawal requests of an article are reviewed by the Editorial Board of the journal. A letter signed by all authors stating their request and reasons for withdrawal should be sent to the journal editor. Authors should not send their work to another journal for evaluation unless the request to withdraw is approved.

APPEALS AND COMPLAINT
The Editorial Board of the journal handles all appeal and complaint cases within the scope of COPE guidelines. In such cases, authors should get in direct contact with the editorial office regarding their appeals and complaints. When needed, an ombudsperson may be assigned to resolve claims that cannot be resolved internally. The Editor in Chief is the final authority in the decision-making process for all appeals and complaints.

DISCLAIMER
Statements or opinions expressed in the manuscripts published in Pharmata reflect the views of the author(s) and not the opinions of the editors, the editorial board, or the publisher; the editors, the editorial board, and the publisher disclaim any responsibility or liability for such materials. The final responsibility regarding the published content rests with the authors.

MANUSCRIPT PREPARATION
The manuscripts should be prepared in accordance with ICMJE-Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals (updated in May 22 - http://www.icmje.org/icmje-recommendations.pdf). Authors are required to prepare manuscripts in accordance with the CONSORT guidelines for randomized research studies, STROBE guidelines for observational original research studies, STARD guidelines for studies on diagnostic accuracy, PRISMA guidelines for systematic reviews and meta-analysis, ARRIVE guidelines for experimental animal studies, and TREND guidelines for non-randomized public behavior. To find the right guideline for your research, please complete the questionnaire by Equator Network here.

The style of the manuscripts should be prepared according to AMA Manual of Style 11th Edition.

Manuscripts can only be submitted through the journal’s online manuscript submission and evaluation system, available at www.pharmata-ataunipress.org/. Manuscripts submitted via any other medium and submissions by anyone other than one of the authors will not be evaluated.

Manuscripts submitted to the journal will first go through a technical evaluation process where the editorial office staff will ensure that the manuscript has been prepared and submitted in accordance with the journal’s guidelines. Submissions that do not conform to the journal’s guidelines will be returned to the submitting author with technical correction requests.

Authors are required to submit the following:
· Copyright Agreement and Acknowledgement of Authorship Form,
· ICMJE Potential Conflict of Interest Disclosure Form (should be filled in by all contributing authors) during the initial submission.

Preparation of the Manuscript
Title page: A separate title page should be submitted with all submissions and this page should include:
· The full title of the manuscript as well as a short title (running head) of no more than 50 characters,
· Name(s), affiliations, highest academic degree(s), and ORCID IDs of the author(s),
· Grant information and detailed information on the other sources of support,
· Name, address, telephone (including the mobile phone number), and email address of the corresponding author,
· Acknowledgment of the individuals who contributed to the preparation of the manuscript but who do not fulfill the authorship criteria.

Abstract: Abstract should be submitted with all articles. Please check Table 1 below for word count specifications.

Keywords: Each submission must be accompanied by a minimum of three to a maximum of five keywords for subject indexing at the end of the abstract. The keywords should be listed in full without abbreviations. The keywords should be selected from the National Library of Medicine, Medical Subject Headings database (https://www.nlm.nih.gov/mesh/MBrowser.html).

Manuscript Types
Research Articles: This is the most important type of article since it provides new information based on original research. Acceptance of original papers will be based upon the originality and importance of the investigation. The main text of original articles should be structured with Introduction, Methods, Results, Discussion, and Conclusion subheadings. Please check Table 1 for the limitations for Original Articles. For Turkish articles, authors must provide an English abstract and keywords. For English articles, authors must provide a Turkish abstract and keywords.

Reporting Statistical Analysis
Statistical analysis to support conclusions is usually necessary. Statistical analyses must be conducted in accordance with international statistical reporting standards (Altman DG, Gore SM, Gardner MJ, Pocock SJ. Statistical guidelines for contributors to medical journals. Br Med J 1983: 7; 1489-93). Information on statistical analyses should be provided with a separate subheading under the Materials and Methods section and the statistical software that was used during the process must be specified.

Values for reporting statistical data, such as P values and CIs should be presented and rounded appropriately. P values should be expressed to 2 digits to the right of the decimal point unless the first 2 digits are zeros, in which case 3 digits to the right of the decimal place should be provided (eg, instead of P < .01, report as P = .002). However, values close to .05 may be reported to 3 decimal places because the .05 is an arbitrary cut point for statistical significance (eg, P = .053). P values less than .001 should be designated as P < .001 rather than exact values (eg, P = .000006).

Units should be prepared in accordance with the International System of Units (SI).

Review Articles: Reviews prepared by authors who have extensive knowledge on a particular field and whose scientific background has been translated into a high volume of publications with a high citation potential are welcomed. These authors may even be invited by the journal. Reviews should describe, discuss, and evaluate the current level of knowledge of a topic in clinical practice and should guide future studies. The subheadings of the review articles should be planned by the authors. However, each review article should include an “Introduction” and a “Conclusion” section. Please check Table 1 for the limitations for Review Articles.

Case Reports: There is limited space for case reports in the journal and reports on rare cases or conditions that constitute challenges in diagnosis and treatment, those offering new therapies or revealing knowledge not included in the literature, and interesting and educative case reports are accepted for publication. The text should include Introduction, Case Presentation, Discussion and Conclusion with an unstructured abstract. Please check Table 1 for the limitations for Case Reports.

Short Communications: Short Communications are brief, focused articles that present new scientific research or theories. These articles should be written in the same format as a full-length original research article, with sections for Introduction, Materials and Methods, Results, and Discussion. The total length of the article should not exceed 2500 words, with a 150-word abstract and a maximum of 3 display items (figures/tables). Please refer to Table 1 for the limitations for “Short Communications.”
27930

*Word limit should not include the abstract, references, tables, and figure legends.

Tables
Tables should be included in the main document, presented after the reference list, and they should be numbered consecutively in the order they are referred to within the main text. A descriptive title must be placed above the tables in title case in italics. Abbreviations used in the tables should be defined below the tables by footnotes (even if they are defined within the main text). Tables should be created using the “insert table” command of the word processing software and they should be arranged clearly to provide easy reading. Data presented in the tables should not be a repetition of the data presented within the main text but should be supporting the main text.

Figures and Figure Legends
Figures, graphics, and photographs should be submitted as separate files (in TIFF or JPEG format) through the submission system. The files should not be embedded in a Word document or the main document. When there are figure subunits, the subunits should not be merged to form a single image. Each subunit should be submitted separately through the submission system. Images should not be labeled (a, b, c, etc.) to indicate figure subunits. Thick and thin arrows, arrowheads, stars, asterisks, and similar marks can be used on the images to support figure legends. Like the rest of the submission, the figures too should be blind. Any information within the images that may indicate an individual or institution should be blinded. The minimum resolution of each submitted figure should be 300 DPI. To prevent delays in the evaluation process, all submitted figures should be clear in resolution and large in size (minimum dimensions: 100 × 100 mm). Figure legends should be listed at the end of the main document.

All acronyms and abbreviations used in the manuscript should be defined at first use, both in the abstract and in the main text. The abbreviation should be provided in parentheses following the definition.

All references, tables, and figures should be referred to within the main text, and they should be numbered consecutively in the order they are referred to within the main text.

Limitations, drawbacks, and the shortcomings of original articles should be mentioned in the Discussion section before the conclusion paragraph.

References
Both in-text citations and the references must be prepared according to the AMA Manual of Style 11th Edition.

While citing publications, preference should be given to the latest, most up-to-date publications. Authors are responsible for the accuracy of references If an ahead-of-print publication is cited, the DOI number should be provided. Journal titles should be abbreviated in accordance with the journal abbreviations in Index Medicus/MEDLINE/PubMed. When there are six or fewer authors, all authors should be listed. If there are seven or more authors, the first three authors should be listed followed by “et al.” In the main text of the manuscript, references should be cited in superscript after punctuation. The reference styles for different types of publications are presented in the following examples.

Journal Article: Bayram F, Bayraktaroğlu T, Sargın M, et al. A Cross-Sectional Study of the Prevalence of Cardiovascular Disease in Adults with Type 2 Diabetes in Türkiye: The CAPTURE Study. Turk J Endocrinol Metabl. 2022;26(1):1-12.

Book Section: Fikremariam D, Serafini M. Multidisciplinary approach to pain management. In: Vadivelu N, Urman RD, Hines RL, eds. Essentials of Pain Management. New York, NY: Springer New York; 2011:17-28.

Books with a Single Author: Patterson JW. Weedon’s Skin Pahology. 4th ed. Churchill Livingstone; 2016.

Editor(s) as Author: Etzel RA, Balk SJ, eds. Pediatric Environmental Health. American Academy of Pediatrics; 2011.

Conference Proceedings: Morales M, Zhou X. Health practices of immigrant women: indigenous knowledge in an urban environment. Paper presented at: 78th Association for Information Science and Technology Annual Meeting; November 6-10; 2015; St Louis, MO. Accessed March 15, 2016. https://www.asist.org/files/meetings/am15/proceedings/openpage15.html

Thesis: Maiti N. Association Between Behaviours, Health Characteristics and Injuries Among Adolescents in the United States. Dissertation. Palo Alto University; 2010.

Online Journal Articles: Tamburini S, Shen N, Chih Wu H, Clemente KC. The microbiome in early life: implications for health outcometes. Nat Med. Published online July 7, 2016. doi:10.1038/nm4142

Websites: International Society for Infectious Diseases. ProMed-mail. Accessed February 10, 2016. http://www.promedmail.org

Epub Ahead of Print Articles: Cai L, Yeh BM, Westphalen AC, Roberts JP, Wang ZJ. Adult living donor liver imaging. Diagn Interv Radiol. 2016 Feb 24. doi: 10.5152/dir.2016.15323. [Epub ahead of print].

REVISIONS
When submitting a revised version of a paper, the author must submit a detailed “Response to the reviewers” that states point by point how each issue raised by the reviewers has been covered and where it can be found (each reviewer’s comment, followed by the author’s reply and line numbers where the changes have been made) as well as an annotated copy of the main document. Revised manuscripts must be submitted within 30 days from the date of the decision letter. If the revised version of the manuscript is not submitted within the allocated time, the revision option may be canceled. If the submitting author(s) believe that additional time is required, they should request this extension before the initial 30-day period is over.

Accepted manuscripts are copy-edited for grammar, punctuation, and format by professional language editors. Once the publication process of a manuscript is completed, it is published online on the journal’s webpage as an ahead-of-print publication before it is included in its scheduled issue. A PDF proof of the accepted manuscript is sent to the corresponding author and their publication approval is requested within 2 days of their receipt of the proof.

Editor in Chief: Yücel KADIOĞLU
Address: Department of Analytical Chemistry, Atatürk University, Faculty of Pharmacy, Erzurum, Turkey
E-mail: yucel@atauni.edu.tr

Publisher: Atatürk University
Address: Atatürk University, Yakutiye, Erzurum, Turkey

Publishing Service: AVES
Address: Büyükdere Cad., 105/9 34394 Şişli, İstanbul, Turkey
Phone: +90 212 217 17 00
E-mail: info@avesyayincilik.com
Webpage: www.avesyayincilik.comhttps://www.pharmata-ataunipress.org/ 


ETHICAL GUIDELINES
An approval of research protocols by the Ethics Committee in accordance with international agreements (World Medical Association Declaration of Helsinki “Ethical Principles for Medical Research Involving Human Subjects,” amended in October 2013, www.wma.net) is required for experimental, clinical, and drug studies and for some case reports. If required, ethics committee reports, or an equivalent official document will be requested from the authors. Submissions which do not have ethical approval will be reviewed according to COPE’s Research, Audit and Service Evaluations guideline.

Such manuscripts can be rejected after editorial review due to the lack of ethics committee approval.

For studies carried out on animals, an approval of research protocols by the Ethics Committee in accordance with international agreements (Guide for the care and use of laboratory animals, 8th edition, 2011" and/or “International Guiding Principles for Biomedical Research Involving Animals, 2012”) is required. Also, the measures taken to prevent pain and suffering of the animals should be stated clearly in such studies.

Ethics committee information should be written with the date and approval number. Information on patient consent, the name of the ethics committee, and the ethics committee approval number and date should also be stated in the Methods section of the manuscript.

ERRATUM
The correction requests submitted by the authors are reviewed by the Editorial Board and the corrections are applied based on the decision of the Editorial Board. In case of corrections in the published text, the readers are informed by publishing the Erratum text in the number following the correction. The edited article is updated on the journal web page and in the indexes when the journal is scanned.

PLAGIARISM AND ETHICAL MISCONDUCT
Pharmata is extremely sensitive about plagiarism. All submissions are screened by a similarity detection software (iThenticate by CrossCheck) at any point during the peer-review and/or production process.

Even if you are the author of the phrases or sentences, the text should not have unacceptable similarity with the previously published data. When you are discussing others' (or your own) previous work, please make sure that you cite the material correctly in every instance.

Authors are strongly recommended to avoid any form of plagiarism and ethical misconduct that are exemplified below.

Self- plagiarism (text-recycling): Overlapping sections or sentences with the author’s previous publications without citing them. Even if you are the author of the phrases or sentences, the text should not have unacceptable similarity with the previously published data.

Salami slicing: Using the same data of a research into several different articles. Reporting the same hypotheses, population, and methods of a study into different papers is not acceptable.

Data Fabrication: It is the addition of data that never occurred during the gathering of data or the experiments. Results and their interpretation must be based on the complete data sets and reported accordingly.

Data Manipulation/Falsification: It means manipulating research data with the intention of giving a false impression. This includes manipulating images (e.g. micrographs, gels, radiological images), removing outliers or ‘inconvenient’ results, changing data points, etc.

In the event of alleged or suspected research misconduct, e.g., plagiarism, citation manipulation, and data falsification/fabrication, the Editorial Board will follow and act according to COPE flowcharts.

AUTHORSHIP
Each person listed as an author should fulfill the authorship criteria recommended by the International Committee of Medical Journal Editors (ICMJE - www.icmje.org). The ICMJE recommends that authorship is based on the following four criteria:

1. Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; AND
2. Drafting the work or revising it critically for important intellectual content; AND
3. Final approval of the version to be published; AND
4. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

In addition to being accountable for the parts of the work he/she has done, an author should be able to identify which co-authors are responsible for specific other parts of the work. Also, authors should have confidence in the integrity of the contributions of their co-authors.

All those designated as authors should meet all four criteria for authorship, and all who meet the four criteria should be identified as authors. Those who do not meet all four criteria should be acknowledged in the title page of the manuscript.

Pharmata requires corresponding authors to submit a signed and scanned version of the Copyright Agreement and Acknowledgement of Authorship form (available for download https://www.pharmata-ataunipress.org) during the initial submission process to act appropriately on authorship rights and to prevent ghost or honorary authorship. If the editorial board suspects a case of “gift authorship,” the submission will be rejected without further review. As part of the submission of the manuscript, the corresponding author should also send a short statement declaring that he/she accepts to undertake all the responsibility for authorship during the submission and review stages of the manuscript.

CHANGE OF AUTHORSHIP
Pharmata reviews the authorship according to the author’s declaration in the Title Page, thus it is the authors responsibility to send the final order of the complete author names. Requests in the change of authorship (e.g. removal/addition of the authors, change in the order etc) after submission are subject to editorial approval. Editorial Board will investigate this kind of cases and act following COPE flowcharts.

Change of authorship requests should be submitted to the Editorial Office with an official letter stating the reasons for the change. The letter must be signed by all authors and include their approval on the change in authorship. If the request is approved by the Editorial Board, authors need to submit a new Copyright Agreement Form according to the final order list.

DECLARATION OF INTEREST
Pharmata requires and encourages the authors and the individuals involved in the evaluation process of submitted manuscripts to disclose any existing or potential conflicts of interests, including financial, consultant, and institutional, that might lead to potential bias or a conflict of interest. Any financial grants or other support received for a submitted study from individuals or institutions should be disclosed to the Editorial Board. To disclose a potential conflict of interest, the ICMJE Potential Conflict of Interest Disclosure Form should be filled in and submitted by all contributing authors. The journal’s Editorial Board resolves cases of a potential conflict of interest of the editors, authors, or reviewers within the scope of COPE and ICMJE guidelines.

COPYRIGHT AND LICENSE
Pharmata requires each submission to be accompanied by a Copyright Agreement and Acknowledgement of Authorship form (available for download at https://www.pharmata-ataunipress.org/). By signing this form, authors retain the copyright of their work and agree that the article, if accepted for publication by the Pharmata will be licensed under a Creative Commons Attribution-NonCommercial (CC BY-NC) 4.0 International License which permits third parties to share and adapt the content for non-commercial purposes by giving the appropriate credit to the original work.

From January 2023 onwards, content is licensed under a Creative Commons CC BY-NC 4.0 license. The journal’s back content was published under a traditional copyright license however the archive is available for free access.

When using previously published content, including figures, tables, or any other material in both print and electronic formats, authors must obtain permission from the copyright holder. Legal, financial and criminal liabilities in this regard belong to the author(s).

POST-PUBLICATION CORRECTION REQUESTS AND RETRACTIONS
All post-publication correction requests are subjected to editorial decision. Editors review the cases considering journal policies and the highest editorial standards that are adhered to ICMJE and COPE guidelines. If the correction/change is accepted to be implement, the article will be updated with an Erratum or Correction Notice and the journal record will be updated in the related indexes.

In the cases of ethical misconduct concerns, the case will be investigated by the editors according to COPE guidelines. A retraction notice will be issued if the investigation results in the verification of the concern. The paper will remain in the online version of the journal and the retraction notice will be enclosed in the article’s record. The article record will be updated in the related indexes.

WITHDRAWAL REQUESTS
Withdrawal requests of an article are reviewed by the Editorial Board of the journal. A letter signed by all authors stating their request and reasons for withdrawal should be sent to the journal editor. Authors should not send their work to another journal for evaluation unless the request to withdraw is approved.

APPEALS AND COMPLAINT
The Editorial Board of the journal handles all appeal and complaint cases within the scope of COPE guidelines. In such cases, authors should get in direct contact with the editorial office regarding their appeals and complaints. When needed, an ombudsperson may be assigned to resolve claims that cannot be resolved internally. The Editor in Chief is the final authority in the decision-making process for all appeals and complaints.

Pharmata is an open access publication, and the journal’s publication model is based on Budapest Access Initiative (BOAI) declaration. All published content is available online, free of charge at https://www.pharmata-ataunipress.org/. The journal’s content is licensed under a Creative Commons Attribution-NonCommercial (CC BY-NC) 4.0 International License which permits third parties to share and adapt the content for non-commercial purposes by giving the appropriate credit to the original work.

From January 2023 onwards, content is licensed under a Creative Commons CC BY-NC 4.0 license. The journal’s back content was published under a traditional copyright license however the archive is available for free access.