Evaluation of continuous renal replacement therapy results applied in the intensive care unit
Abstract
Materials and methods: This study included the patients who admitted to the Internal Medicine Intensive Care Unit of our university between January 2019 and June 2020. Among these patients, those over 18 years of age and those who had acute renal failure during their hospitalization and received continuous renal replacement therapy were included in the study.
Results: Mean SOFA scores at admission were 2.7 which is an indication for severe disease. Lengths of ICU stay were long and approximately 77 percent of these patients died in ICU. When the comorbid conditions of the patients were examined, it was seen that oncological diseases were the most common. It was followed by hypertension, diabetes mellitus and heart diseases. Considering the KDIGO scores of the patients diagnosed with AKI, it was seen that 60 percent of them were grade 5. Treatment could be applied for an average of 25 hours.
Conclusion: Indications, timing and benefits of CRRT are the questions that need to be research and yet remained unsolved. With evolving of technology, CRRT will be our most useful helper in ICUs.
Keywords
References
- 1. Legrand M, Darmon M, Joannidis M, Payen D. Management of renal replacement therapy in ICU patients: an international survey. Intensive Care Med. 2013;39(1):101-108. doi:10.1007/s00134-012-2706-x
- 2. Ronco C. Continuous Renal Replacement Therapy: Forty-year Anniversary. Int J Artif Organs. 2017;40(6):257-264. doi:10.5301/ijao.5000610
- 3. RENAL Replacement Therapy Study Investigators, Bellomo R, Cass A, et al. Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med. 2009;361(17):1627-1638. doi:10.1056/NEJMoa0902413
- 4. VA/NIH Acute Renal Failure Trial Network, Palevsky PM, Zhang JH, et al. Intensity of renal support in critically ill patients with acute kidney injury [published correction appears in N Engl J Med. 2009 Dec 10;361(24):2391]. N Engl J Med. 2008;359(1):7-20. doi:10.1056/NEJMoa0802639
- 5. Manns M, Sigler MH, Teehan BP. Continuous renal replacement therapies: an update. Am J Kidney Dis 1998; 32:185.
- 6. Davenport A, Honore PM. Continuous renal replacement therapy under special conditions like sepsis, burn, cardiac failure, neurotrauma, and liver failure. Semin Dial 2021; 34:457.
- 7. John A Kellum, Norbert Lameire, Peter Aspelin, Rashad S Barsoum, Emmanuel A Burdmann, et al. (2012) Kidney Disease: Improving Global Outcomes (KDIGO); Acute Kidney Injury Work Group: KDIGO clinical practice guidelines for acute kidney injury. Kidney Int Suppl 2(1): 1-138.
- 8. Investigators S-A. Canadian critical care trials G, Australian, et al. timing of initiation of renal-replacement therapy in acute kidney injury. N Engl J Med 2020; 383(3):240–51.
Details
Primary Language
English
Subjects
Clinical Sciences
Journal Section
Clinical Research
Authors
Çağla Erdoğan
*
0000-0001-8772-6565
Türkiye
Publication Date
January 31, 2023
Submission Date
November 2, 2022
Acceptance Date
November 22, 2022
Published in Issue
Year 2023 Volume: 16 Number: 1
