Research Article

Controlling nutritional (CONUT) score for nutritional screening in kidney transplant recipients

Volume: 17 Number: 4 October 9, 2024
TR EN

Controlling nutritional (CONUT) score for nutritional screening in kidney transplant recipients

Abstract

Purpose: Nutrition is severely impaired in individuals with renal impairment, and transplant often ameliorates this condition. In this study, we aimed to evaluate the controlling nutritional status (CONUT) score of kidney transplant (KT) recipients. Materials and methods: Using the data from the nephrology transplant unit, we analyzed 188 patients whose data on the constituents of the CONUT score were available. We included KT individuals with at least one lymphocyte count and total cholesterol and albumin concentrations. This data has been used to calculate the CONUT score. The decrease of lymphocyte counts, and total cholesterol was determined with 0, 1, 2, and 3 points, and the reduction of albumin was assigned with 0, 2, 4, and 6 points in agreement with disease severity. Patients were classified according to this score: normal, light, moderate, and severe. Results: There were 130 patients in normal, 54 in light, and three in moderate and one in severe group. The CONUT score was good for regular-weight patients both before and after transplantation. All laboratory findings revealed significant differences between CONUT groups (p<0.05). Conclusion: After transplantation, the number of patients in the underweight group decreased when normal weight and obesity increased. However, some patients’ nutrition was not ameliorated. The CONUT score may be a useful tool for monitoring transplant patients’ nutritional status.

Keywords

References

  1. 1. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 2013;3:4. https://doi.org/10.1038/kisup.2012.76
  2. 2. Çiçek EA, Rota S, Dursun B, Kavalci E. Evaluation of serum NGAL and hepcidin levels in chronic kidney disease patients. Ren Fail 2016;38:35-39. https://doi.org/10.3109/0886022X.2015.1107823
  3. 3. Munib S, Ahmed T, Ahmed R, NUD. Renal allograft biopsy findings in live-related renal transplant recipients. J Coll Physicians Surg Pak 2021;31:197-201. https://doi.org/10.29271/jcpsp.2021.02.197
  4. 4. Allawi AAD. Malnutrition, inflamation and atherosclerosis (MIA syndrome) in patients with end stage renal disease on maintenance hemodialysis (a single centre experience). Diabetes Metab Syndr 2017;12:91-97. https://doi.org/10.1016/j.dsx.2017.09.003
  5. 5. Keshavarz Shahbaz S, Pourrezagholi F, Nafar M, et al. Dynamic variation of kidney injury molecule-1 mRNA and protein expression in blood and urine of renal transplant recipients: a cohort study. Clin Exp Nephrol 2019;23:1235-1249. https://doi.org/10.1007/s10157-019-01765-y
  6. 6. Veroux M, Corona D, Sinagra N, et al. Nutrition in kidney transplantation. Int J Artif Organs 2013;36:677-686. https://doi.org/10.5301/ijao.5000234
  7. 7. Marino LV, Romão EA, Chiarello PG. Nutritional status, energy expenditure, and protein oxidative stress after kidney transplantation. Redox Rep. 2017;22:439-444. https://doi.org/10.1080/13510002.2017.1325572
  8. 8. Hwang JH, Ryu J, An JN, et al. Pretransplant malnutrition, inflammation, and atherosclerosis affect cardiovascular outcomes after kidney transplantation. BMC Nephrol 2015;16:1-12. https://doi.org/10.1186/s12882-015-0108-3

Details

Primary Language

English

Subjects

​Internal Diseases , Clinical Sciences (Other)

Journal Section

Research Article

Early Pub Date

September 9, 2024

Publication Date

October 9, 2024

Submission Date

July 5, 2024

Acceptance Date

September 9, 2024

Published in Issue

Year 2024 Volume: 17 Number: 4

AMA
1.Avcı E, Dursun B, Nar R, Demir S. Controlling nutritional (CONUT) score for nutritional screening in kidney transplant recipients. Pam Med J. 2024;17(4):714-720. doi:10.31362/patd.1497044

Creative Commons Lisansı
Pamukkale Medical Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License